About ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE
ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE belongs to the class of medications called 'anti-malarial primarily used to treat malaria. ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE gives a degree of protection (prophylaxis) against malaria when people travel to areas where malarial cases exist. It is effective against Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE is not effective against Plasmodium falciparum. Besides this, it also treats amoebiasis (intestinal dysentery) and rheumatic disease (arthritis).
ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE contains 'arterolane maleate' and 'piperaquine phosphate'. ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE together treats malaria. They work by increasing the levels of heme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.
The dose of ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE can vary depending upon your condition and the severity of the infection. The common side effects of ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE include nausea, vomiting, abdominal pain, loss of appetite, indigestion, cough, dizziness, headache. Everyone need not experience the above side effects. In case of any discomfort, speak with a doctor.
Before starting ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE, please inform your doctor if you are allergic to ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE. Do not take ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE on your own. ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE is used with caution during pregnancy and breastfeeding. Tell your doctor if you are taking medicines other than ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE. ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE used with caution in liver diseases, kidney diseases. ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE should be used with extreme caution in patients suffering from cardiovascular diseases due to the increased risk of severe adverse effects including an irregular heart rhythm. The use of this ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE may cause persistent vomiting in some patients.
Uses of ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE
Malaria
Medicinal Benefits
ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE contains 'arterolane maleate' and 'piperaquine phosphate' belongs to the class of medications called 'anti-malarial primarily used to treat malaria. ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE together treats malaria. They work by increasing the levels of heme in the blood, a substance toxic to the malarial parasite. This kills the parasite and stops the infection from spreading.
Directions for Use
Storage
Side Effects of ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE
- Nausea
- Vomiting
- Abdominal pain
- Loss of appetite
- Indigestion
- Cough
- Dizziness
- Headache
In-Depth Precautions and Warning
Drug Warnings
Before starting ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE, please inform your doctor if you are allergic to ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE. Do not take ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE on your own. ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE is used with caution during pregnancy and breastfeeding. Tell your doctor if you are taking medicines other than ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE. ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE used with caution in liver diseases, kidney diseases. ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE should be used with extreme caution in patients suffering from cardiovascular diseases due to the increased risk of severe adverse effects including an irregular heart rhythm. The use of this ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE may cause persistent vomiting in some patients. Appropriate dose adjustments or replacement with a suitable alternative may be necessary in these cases based on the clinical condition.
Drug Interactions
Drug-Drug interaction: ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE can interact with pain killers (aspirin), anti-allergic (hydroxyzine), anticancer (tamoxifen), antibiotics (ciprofloxacin, amoxicillin/clavulanate), immunosuppressants (mycophenolate mofetil), antimalarials (primaquine, mefloquine, hydroxychloroquine), antianxiety medicine (pregabalin), anti-epileptic (levetiracetam), antacids (esomeprazole), and anti-anxiety drugs (alprazolam).
Drug-Food interaction: Limit the consumption of grapefruit or grapefruit juice with ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE as it can significantly increase the level of this medicine in the blood.
Drug-Disease interaction: People affected with heart disease (arrhythmias) seizures, liver disease (hepatotoxicity), cardiovascular diseases, kidney diseases should not take ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE without doctors consultation.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is not known whether it is safe to consume alcohol with ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE, Please consult your doctor before taking ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE.
Pregnancy
unsafeARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor before taking ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE.
Breast Feeding
unsafeARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE is not recommended for use in breastfeeding women unless absolutely necessary. All the risks and benefits should be discussed with the doctor before taking this medicine.
Driving
cautionIt is not known whether ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
Liver
cautionARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE should be used with caution in patients with liver disease. A dose adjustment of ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE may be needed. Please consult your doctor before taking ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE.
Kidney
cautionARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE should be used with caution in patients with kidney disease. A dose adjustment of ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE may be needed. Please consult your doctor before taking ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE.
Children
cautionsafe to use in children (<12) yet dose adjustment by a doctor will be done on the basis of age, weight, and severity of the infection.
Habit Forming
Diet & Lifestyle Advise
- Always take ARTEROLANE MALEATE+PIPERAQUINE PHOSPHATE with meals for reduced gastric irritation.
- Adequate nutrition is the key to improvement in malaria-induced weakness.
- It is important to allow the patient to eat regularly in small amounts to tolerate the food.
- Increase fluid and protein intake for malaria-induced weight loss.
- Proper rest and mosquito-free premises are important for the patient to recover.
Special Advise
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- Avoid mosquito bites by using a mosquito net, insect repellent, and by covering your arms and legs
Patients Concern
Disease/Condition Glossary
Malaria: It is a severe & fatal parasitic infection caused by a protozoan called Plasmodium. 4 types of parasites can infect humans with malaria: Plasmodium falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malaria. Female anopheles mosquito bites cause it. If bitten by an infected mosquito (the Anopheles mosquito), malaria parasites are injected into the blood. These parasites then migrate to the liver where they multiply via the bloodstream. A patient doesn't feel sick at this period because the parasites are in the liver. Then the parasites leave the liver and enter the red blood cells where the parasites are developing, and then the red blood cells burst, allowing them to transfer to another blood cell. The parasites release harmful chemicals into the bloodstream at this point, and the patient begins to feel ill. Malaria leads to periodic fever-chills, anaemia, kidney failure, and jaundice due to excessive red blood cell death due to plasmodium growth inside them.
