About ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN
ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN is a combination medicine used to treat hypertension (high blood pressure) and lower the risk of heart attack and stroke. Hypertension is a medical condition in which blood pressure is elevated persistently in the arteries. Heart attack refers to blocked blood flow to the heart due to blockage of arteries. A stroke occurs due to blocked blood flow to the brain.
ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN contains Aspirin (antiplatelet), Atenolol (beta-blocker), Atorvastatin (statin), and Losartan (Angiotensin receptor blocker). Aspirin decreases the formation of harmful blood clots by preventing platelets from sticking together. Atenolol acts by inhibiting beta receptors in the heart, causing the heart to beat more slowly and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Atorvastatin belongs to the class of statins or HMG-CoA reductase inhibitors that work by inhibiting the HMG-CoA reductase enzyme in the body that is essential to make cholesterol. Thereby, it decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by lowering the excess cholesterol deposition in the major blood vessels of the brain and heart. Losartan works by blocking the angiotensin II receptors. Thus, it reduces the production of angiotensin II, which causes constriction and narrowing of blood vessels. This allows the blood vessels to relax and widen and lower blood pressure. Together, ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN helps to reduce cholesterol levels, lower high blood pressure and reduces the risk of heart attack and stroke.
Take ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN as prescribed. You are advised to take ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN for as long as your doctor has recommended it based on your medical condition. Sometimes, ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN may cause common side effects such as indigestion, increased tendency for bleeding, headache, nausea, constipation, diarrhoea, tiredness, dizziness, or back pain. Most of these side effects of ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
If you are allergic to aspirin, atenolol, atorvastatin, losartan or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN. Avoid drinking alcohol with ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN as it may cause tiredness. Drive only if you are alert, as ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN may cause dizziness or tiredness. If you are about to undergo surgery where an anaesthetic is used, please tell your doctor that you are taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN.
Uses of ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN
Hypertension (high blood pressure), lower risk of heart attack or stroke
Medicinal Benefits
ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN contains Aspirin, Atenolol, Atorvastatin, and Losartan, used to treat hypertension (high blood pressure) and lower the risk of heart attack and stroke. Aspirin decreases the formation of harmful blood clots. Atenolol acts by inhibiting beta receptors in the heart, causing the heart to beat more slowly and with less force. Thereby, it decreases the pressure at which blood is pumped out of the heart and throughout the body. Atorvastatin decreases the production of LDL (bad cholesterol) by the liver. Also, it reduces the risk of stroke or heart attack by lowering the excess cholesterol deposition in the major blood vessels of the brain and heart. Losartan lowers blood pressure by widening and relaxing blood vessels. Together, ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN helps to reduce cholesterol levels, lower high blood pressure and reduces the risk of heart attack and stroke.
Directions for Use
Storage
Side Effects of ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN
- Indigestion
- Increased tendency for bleeding
- Headache
- Nausea
- Constipation
- Diarrhoea
- Tiredness
- Dizziness
- Back pain
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to aspirin, atenolol, atorvastatin, losartan or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN. Avoid drinking alcohol with ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN as it may cause tiredness. Drive only if you are alert, as ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN may cause dizziness or tiredness. If you are about to undergo surgery where an anaesthetic is used, please tell your doctor that you are taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN.
Drug Interactions
Drug-Drug Interaction: Inform your doctor if you are taking blood thinners (warfarin, heparin, clopidogrel), antidiabetic drugs (insulin, empagliflozin), antidepressants (duloxetine, alprazolam), calcium channel blockers (amlodipine), diuretic (furosemide), skeletal muscle relaxant (cyclobenzaprine), sedative (zolpidem), proton pump inhibitor (esomeprazole), antihistamine (diphenhydramine), and anticonvulsant (pregabalin).
Drug-Food Interaction: Avoid taking more than one or two small glasses of grapefruit juice per day, as large quantities of grapefruit juice can change the effects of Atorvastatin. ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN may interact with St. John’s wort (herbal supplement used to treat depression). Also, avoid alcohol consumption as it may increase tiredness.
Drug-Disease Interaction: If you have ever had an ulcer in your stomach or small intestine, have blood circulation problems, asthma, heavy menstrual periods, hypothyroidism (under-active thyroid gland), phaeochromocytoma (tumour in the adrenal gland), severe respiratory failure, diabetes, liver, heart or kidney problems, inform your doctor before taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption while taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN as it may increase tiredness.
Pregnancy
unsafeASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN is not recommended for use during pregnancy, especially in the last trimester, as aspirin taken near the time of delivery may cause bleeding to both mother and baby. Therefore, please inform your doctor if you are pregnant or planning for pregnancy before taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN.
Breast Feeding
consult your doctorLimited information is available on the effect of ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN on breastfeeding mothers. Hence, if you are a nursing mother, inform your doctor before taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN.
Driving
cautionASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN.
Liver
consult your doctorIf you have a history of or are suffering from liver disease, inform your doctor before taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN. Your doctor may adjust the dose if required based on your condition.
Kidney
consult your doctorIf you have kidney problems, inform your doctor before taking ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN. Your doctor may adjust the dose if required based on your condition.
Children
consult your doctorLimited information is available. Therefore, please consult a doctor if you have any concerns regarding the use of ASPIRIN+ATENOLOL+ATORVASTATIN+LOSARTAN for children.
Habit Forming
Diet & Lifestyle Advise
- Maintain a low-salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
- Do regular exercises such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes daily.
- Chronic stress may also cause high blood pressure. Therefore, avoid stress triggers and make time for yourself to relax and do activities that you enjoy.
- Maintain a diet rich in vegetables, fruits, and whole grains, and cut down on beverages and processed and sugary foods.
- Maintain a low-fat diet. Limit your intake of dairy products made with whole milk and red meat. Prefer skim milk and fat-free or low-fat dairy products.
- Try to include heart-healthy omega-3 fatty acid-containing foods in your daily diet. You can also use low-fat cooking oil like olive oil, soybean oil, canola oil and coconut oil, which may help lower high blood pressure.
- Quit smoking and avoid alcohol consumption.
Patients Concern
Disease/Condition Glossary
Hypertension: It is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). High blood pressure also causes brain damage (stroke) and kidney failure. Normal blood pressure lies between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.
Heart attack: It refers to blocked blood flow to the heart due to the blockage of arteries. The blockage is most often a build-up of fat, cholesterol, and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). The symptoms include discomfort in the chest or upper areas of the body, shortness of breath, or lightheadedness.
Stroke: It occurs due to blocked blood flow to the brain. Symptoms include arm weakness and speech difficulty. Heart attack or stroke may occur due to high cholesterol, high blood pressure, diabetes, obesity, smoking, family history, or lack of physical activity.