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About BAMLANIVIMAB+ETESEVIMAB

BAMLANIVIMAB+ETESEVIMAB belongs to the group of monoclonal antibodies used in the post-exposure prevention and treatment of mild to moderate respiratory illness caused by COVID-19. BAMLANIVIMAB+ETESEVIMAB is used in non-hospitalised cases of COVID-19 that are at risk of progressing to severe disease. Coronavirus disease is an infectious disease caused by SARS-CoV-2. It can range from a mild cold to a serious form of pneumonia.

BAMLANIVIMAB+ETESEVIMAB contains Bamlanivimab and Etesevimab. BAMLANIVIMAB+ETESEVIMAB works by using monoclonal proteins to imitate the natural defence mechanisms of the body. It blocks the spike protein of the virus from attaching to the human receptor cell, thereby arresting the progress of the disease.

BAMLANIVIMAB+ETESEVIMAB will be administered by a qualified healthcare professional. Do not self-administer. BAMLANIVIMAB+ETESEVIMAB may cause certain common side effects such as nausea, headache, pain and soreness at the injection site. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen. 

It is advisable to inform the doctor if you are allergic to any of its components.  Keep your doctor informed if you suffer from HIV, asthma, obesity, cancer, liver disease, kidney problems, heart disease, neurodevelopmental disorders, sickle cell disease, gastrostomy, tracheostomy or positive pressure ventilation. Consult your doctor if you are pregnant, planning to get pregnant or are breastfeeding. Avoid BAMLANIVIMAB+ETESEVIMAB use with alcohol. 

Uses of BAMLANIVIMAB+ETESEVIMAB

COVID-19

Medicinal Benefits

BAMLANIVIMAB+ETESEVIMAB is a monoclonal antibody used in the post-exposure prophylaxis and treatment of mild to moderate disease caused by SARS-CoV-2. BAMLANIVIMAB+ETESEVIMAB contains Bamlanivimab and Etesevimab. BAMLANIVIMAB+ETESEVIMAB works by using monoclonal proteins to imitate the natural defence mechanisms of the body. The COVID virus contains a capsid with spike proteins, through which it penetrates the body to cause infection. BAMLANIVIMAB+ETESEVIMAB binds to the spike protein of the virus. Bamlanivimab blocks the spike protein of the virus from attaching to the human receptor cell, thereby arresting the progress of the disease. Etesevimab also binds to a protein on the receptor cell, thereby blocking viral entry. However, it binds on a different but overlapping site and augments the response of Bamlanivimab. Hence, BAMLANIVIMAB+ETESEVIMAB is synergistic in combination and finds use in preventing the progression of mild to moderate covid cases to severe cases requiring hospitalisation.

Directions for Use

BAMLANIVIMAB+ETESEVIMAB will be administered by a qualified healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of BAMLANIVIMAB+ETESEVIMAB

  • Nausea
  • Vomiting
  • Diarrhoea
  • Redness, Soreness and Pain at the injection site
  • Chills
  • Fever

In-Depth Precautions and Warning

Drug Warnings

It is advisable to inform the doctor if you are allergic to any of its components.  Keep your doctor informed if you suffer from HIV, asthma, cancer, liver disease, kidney problems, heart disease, neurodevelopmental disorders, sickle cell disease, gastrostomy, tracheostomy or positive pressure ventilation. Offer a detailed medical and vaccination history. Discuss any recent vaccinations with the doctor. Inform the doctor especially if you are on any radiotherapy, immunosuppressant drugs, blood thinners or any other medicines or herbs. Consult your doctor if you are pregnant, planning to get pregnant or are breastfeeding. BAMLANIVIMAB+ETESEVIMAB is not meant for use as vaccination. BAMLANIVIMAB+ETESEVIMAB is not meant for use in severe hospitalised cases or in patients requiring high flow oxygen or mechanical ventilation as it may lead to worsened outcomes.

Drug Interactions

Drug-Drug Interactions: No interactions found.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: No interactions found.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    caution

    It is not recommended to consume alcohol with BAMLANIVIMAB+ETESEVIMAB. Please consult your doctor if you have any concerns.

  • Safety Warning

    Pregnancy

    caution

    Not enough studies exist to ascertain the effect of BAMLANIVIMAB+ETESEVIMAB on pregnancy. Please consult your doctor if you have any concerns.

  • Safety Warning

    Breast Feeding

    caution

    Not enough studies exist to ascertain the effect of BAMLANIVIMAB+ETESEVIMAB on nursing. Please consult your doctor in case of any concerns.

  • Safety Warning

    Driving

    caution

    It is not known if BAMLANIVIMAB+ETESEVIMAB affects your ability to drive. Drive only if you are alert after taking BAMLANIVIMAB+ETESEVIMAB.

  • Safety Warning

    Liver

    caution

    Exercise caution before using BAMLANIVIMAB+ETESEVIMAB in case of established liver disease. Please consult your doctor to address any concerns.

  • Safety Warning

    Kidney

    caution

    Exercise caution before using BAMLANIVIMAB+ETESEVIMAB in case of established kidney disease. Please consult your doctor to address any concerns.

  • Safety Warning

    Children

    safe if prescribed

    Please consult your doctor if you have any concerns. Your doctor will determine the dose and duration based on your child's condition.

Habit Forming

No

Diet & Lifestyle Advise

  • Keep a healthy state of mind. Fear is one of the biggest causes of decreased immunity. See a therapist when you feel overwhelmed.
  • Meditation, music and yoga have also proven very effective in helping with mental health.
  • Keep yourself at a safe distance from people.
  • Always sneeze or cough into your elbow and keep a handkerchief on you.
  • Wash your hands with soap and water and keep yourself clean.
  • Eat more lean meats, healthy fats, fruits, vegetables and whole-grain foods to give you more energy. Load up on Vitamin-C rich citrus fruit for enhanced immunity.
  • Do not forget to take your Vitamin B complex and Vitamin C supplements every day as these are essential for the body and immunity.
  • Steam inhalation for 3-5 minutes every day and salt-water gargle with warm water has been proven very effective in keeping respiratory infections at bay and in promoting health. 
  • Stay hydrated by drinking plenty of water as dehydration is often seen in pneumonia.
  • Taking a stroll in the garden, or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired. 
  • Avoid tobacco use as smoking hampers lung health and makes breathing even more difficult.

Special Advise

  • In case of a fever or rash following BAMLANIVIMAB+ETESEVIMAB, do not use any antipyretic or anti-allergic medicines without consulting the doctor.

Patients Concern

Disease/Condition Glossary

Coronavirus Disease: Coronavirus disease is an infection caused by the SARS-CoV-2 virus. It can range from a mild cold, cough and fever to full-blown pneumonia. Coronavirus belongs to a group of RNA viruses and has crown-like projections on the surface of the pathogen. The virus transmits through droplets generated from an infectious person’s cough, sneeze or heavy breathing. The common symptoms of coronavirus disease are dry cough, tiredness, breathlessness, fever, loss of sense of taste and smell, diarrhoea, body pains, headache, and sore throat.

FAQs

How does BAMLANIVIMAB+ETESEVIMAB work?

BAMLANIVIMAB+ETESEVIMAB works by inducing an antibody response in the body by instilling monoclonal antibodies that mimic the natural defences of the body and block the spike protein of the virus from attaching to body cells, thus arresting the progression of the disease.

Can BAMLANIVIMAB+ETESEVIMAB affect my ability to get pregnant?

Not enough literature exists to ascertain the effects of BAMLANIVIMAB+ETESEVIMAB on fertility. Please consult your doctor in case of any concerns.

How is BAMLANIVIMAB+ETESEVIMAB different from Remdesivir?

Remdesivir is an antiviral that functions to kill the virus. On the other hand, BAMLANIVIMAB+ETESEVIMAB blocks the virus from attaching to the cells of the body. Thereby preventing the progression of the disease.

How is BAMLANIVIMAB+ETESEVIMAB different from the COVID vaccines?

Vaccines stimulate the body to make its own antibodies against infection. On the other hand, monoclonal antibodies deliver lab-made antibodies against the virus.

Available Medicines for

BAMLANIVIMAB+ETESEVIMAB

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