BEMCENTINIB belongs to the group of immunomodulators. BEMCENTINIB is used in the treatment of coronavirus disease caused by COVID-19. Coronavirus disease is an infectious disease caused by SARS-CoV-2. It can range from a mild cold to a serious form of pneumonia. It may also use to treat Acute myeloid leukaemia, Non-small cell lung cancer, Melanoma.
BEMCENTINIB contains ‘’Bemcentinib.’’ BEMCENTINIB works by inhibiting viral entry into body cells and also prevents the inhibition of a certain type of interferon, which is responsible for the cell’s natural defence mechanism.
BEMCENTINIB is a prescription-only medication. BEMCENTINIB is available as a capsule for oral intake. BEMCENTINIB can be taken with or without food. BEMCENTINIB should be swallowed whole with a glass of water. Do not crush, chew or break it. BEMCENTINIB may cause certain common side effects such as fatigue, diarrhoea and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.
It is advisable to inform the doctor if you are allergic to BEMCENTINIB or any of its components. Keep your doctor informed if you suffer from any medical disorders. Keep your doctor informed if you have recently had any surgery or are scheduled for surgery in the near future. Offer a detailed medical and vaccination history. Tell your doctor about your transfusion history and avoid BEMCENTINIB in case of a recent blood transfusion. Discuss any recent vaccinations with the doctor. Inform the doctor if you are on any drugs that affect the immunity and immune system of the body. Consult your doctor if you are planning to get pregnant or are breastfeeding. Avoid consuming alcohol while using BEMCENTINIB.
COVID-19, Acute Myeloid Leukaemia, Non-Small Cell Lung Cancer, Melanoma
BEMCENTINIB is an immunomodulator used in the treatment of various types of cancers and infections, such as Covid-19. BEMCENTINIB contains Bemcentinib. Bemcentinib works by inhibiting the entry of the virus into the body cells. BEMCENTINIB targets a protein receptor called AXL, a common attachment and entry point for most viruses. In addition, BEMCENTINIB prevents the inhibition of Type-I interferon, which is responsible for the cell’s natural defence mechanism. Bemcentinib also works by blocking the enzyme responsible for catalysing the increase in drug resistance and immune escape, thus helping in maintaining the normal immune function of cells and enhancing drug sensitivity.
It is advisable to inform the doctor if you are allergic to BEMCENTINIB or any of its components. Keep your doctor informed if you suffer from any brain disorders, nerve cell cancer, meningitis (brain fever), any heart problems such as congestive cardiac failure, heart block, or a family history of sustained QTc syndrome; clinically significant hypokalaemia (low potassium levels), any autoimmune disease such as hypothyroidism, Rheumatoid arthritis, lupus and/or pernicious anaemia; interstitial lung disease, pneumonia, Hepatitis B, abdominal disorders, bowel resection and intestinal disease, psychiatric disorders or a chronic disease such as HIV. Keep your doctor informed if you have recently had any surgery or are scheduled for surgery in the near future. Offer a detailed medical and vaccination history. Tell your doctor about your transfusion history and avoid BEMCENTINIB in case of a recent blood transfusion. Discuss any recent vaccinations with the doctor. Inform the doctor, especially if you are on any radiotherapy, chemotherapy, other immunomodulators, vitamin K antagonists, antacids, or steroids. Consult your doctor if you are planning to get pregnant or are breastfeeding. Avoid BEMCENTINIB use with alcohol.
Drug-Drug Interactions: BEMCENTINIB may interact with blood-thinners/anticoagulants (warfarin, acenocoumarol, apixaban, rivaroxaban, heparin).
Drug-Food Interactions: BEMCENTINIB may interact with ethanol.
Drug-Disease Interactions: BEMCENTINIB should be used with caution in patients with a known hypersensitivity disorder, HIV, liver problems, hypokalemia, brain disorders, nerve cell cancer, meningitis (brain fever), any heart problems such as congestive cardiac failure, heart block, or a family history of sustained QTc syndrome; clinically significant hypokalaemia (low potassium levels), any autoimmune disease such as hypothyroidism, Rheumatoid arthritis, lupus and/or pernicious anaemia; interstitial lung disease, pneumonia, Hepatitis B, abdominal disorders, bowel resection and intestinal disease and/or psychiatric disorders.
It is not recommended to consume alcohol while taking BEMCENTINIB. Please consult your doctor if you have any concerns.
Not enough studies exist to ascertain the effect of BEMCENTINIB on pregnancy. Please consult your doctor if you have any concerns.
Not enough studies exist to ascertain the effect of BEMCENTINIB on nursing. BEMCENTINIB is not recommended to use without contraception during breastfeeding. Please consult your doctor in case of any concerns.
BEMCENTINIB may cause fatigue and dizziness. If any side effects hamper your ability to drive, do not drive.
Exercise caution before using BEMCENTINIB if you have pre-existing liver disease as it may cause derangement of liver enzymes. Please consult your doctor to address any concerns.
Exercise caution before using BEMCENTINIB if you have pre-existing kidney disease. Please consult your doctor to address any concerns.
Not enough studies exist to ascertain the effect of BEMCENTINIB in children. Please consult your doctor in case of any concerns.
Coronavirus Disease: Coronavirus disease is an infection caused by the SARS-CoV-2 virus. It can range from a mild cold, cough and fever to full-blown pneumonia. Drop in oxygen saturation and breathlessness was also common symptoms noted. However, the new variant of Omicron is supposed to cause only a mild disease characterised by a scratchy throat and fatigue.
Melanoma: Melanoma is a type of skin cancer caused by harmful UV radiation from the sun. It is common in fair-skinned and freckled individuals. It results in mole formation, typically on the skin of the face.
Acute Myeloid Leukaemia: Acute myeloid leukaemia is a cancer of the blood cells. It starts in the bone marrow, producing excess immature and defunct white blood cells (WBCs). WBCs help in fighting infection and maintaining the immunity of the body. In the case of immature WBCs, the body’s immune system is heavily compromised. Hence, AML results in increased infections, anaemia, joint pains and aches, dehydration, fatigue, weight loss and unusual bleeding.