Levodopa+benserazide
About Levodopa+benserazide
Benserazide+levodopa is used to treat Parkinson’s disease. Parkinson’s disease is a disorder of the central nervous system that affects movement and locomotion. It causes stiffness, tremors (shaking), difficulty with walking, coordination, and balance.
Benserazide+levodopa contains levodopa and benserazide, which work together to manage symptoms of Parkinson’s disease. It helps improve movement control and reduces stiffness and slowness. It also supports smoother body movements during daily activities. Together, Benserazide+levodopa helps improve mobility (movement) and overall quality of life.
Take Benserazide+levodopa as prescribed by your doctor. The common side-effects of Benserazide+levodopa are Involuntary jerking movements of the body, agitation, hallucinations (seeing or hearing things that are not true), nausea, vomiting, loss of appetite, weight gain, constipation, skin rash, itching, confusion, tiredness, water retention, and difficulty sleeping or sudden onset of sleep episodes. If any of these side effects persist or worsen, inform your doctor immediately.
It is not recommended to take Benserazide+levodopa if you are allergic to any of its contents. Benserazide+levodopa is not recommended for use in individuals younger than 25 years, pregnant women, or breastfeeding mothers. Benserazide+levodopa should be used with caution in the elderly, as dose adjustments may be necessary.
Uses of Levodopa+benserazide
Medicinal Benefits
- It helps reduce tremors (shaking), stiffness, and slow movement.
- Improves muscle control and coordination.
- Enhances voluntary movement and walking ability.
- Makes daily activities easier to perform.
- Helps relax rigid muscles.
- Improves flexibility and overall physical comfort.
Directions for Use
- Take Benserazide+levodopa with or without food as advised by your doctor.
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Swallow it as a whole with a glass of water.
- Do not crush, chew, or break it.
Storage
Side Effects of Levodopa+benserazide
- Involuntary jerking movements of the body
- Agitation
- Hallucinations (seeing or hearing things that are not true)
- Nausea
- Vomiting
- Loss of appetite
- Diarrhea
- Irregular heartbeat (faster or slower than normal)
- Weight gain
- Constipation
- Skin rash
- Itching
- Confusion
- Tiredness
- Water retention
- Anaemia (low numbers of red blood cells)
- Changes to how things taste or a loss of taste
- Difficulty sleeping or sudden onset of sleep episodes
Medicines Containing this Salt
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Drug Warnings
- Benserazide+levodopa is not recommended for use in individuals younger than 25 years, pregnant women, or breastfeeding mothers.
- Benserazide+levodopa should be used with caution in the elderly, as dose adjustments may be necessary.
- Before taking Benserazide+levodopa, inform your doctor if you have hormonal problems, diabetes, heart problems, stomach ulcers, or osteomalacia (soft and weak bones).
- Do not take this medication if you have been taking non-selective monoamine oxidase inhibitors (MAOIs) such as isocarboxazid or phenelzine within the past 14 days.
- If you notice impulse control disorders such as gambling addiction, increased libido (sexual desire), sexual addiction, compulsive spending or buying, and binge eating, inform your doctor immediately. In such cases, the doctor may reduce the dose or stop the treatment based on your condition.
Drug Interactions
Drug-Drug Interactions: Inform your doctor if you are taking any of the following medicines, as there may be an interaction.
- Antidepressant medicines (Tranylcypromine, Isocarboxazid)
• Potential effect: May increase blood pressure and raise the risk of serious side effects. - Anticancer medicine (Procarbazine)
• Potential effect: May increase blood pressure and increase the risk of adverse effects. - Antipsychotic medicine (Amisulpride)
• Potential effect: May increase the risk and severity of side effects and also reduce the effectiveness of both medicines. - Antibiotic medicine (Linezolid)
• Potential effect: May increase blood pressure and raise the risk of side effects. - Breathing problem medicine–Anticholinergic (Glycopyrronium bromide)
• Potential effect: May significantly reduce the blood levels of Benserazide+levodopa and lower its effectiveness.
Drug-Food Interactions:
- High-protein foods & Alcohol: Avoid taking Benserazide+levodopa with high-protein foods (such as meat) and avoid alcohol, as they may reduce the medicine’s effect and increase side effects.
Drug-Disease Interactions: Benserazide+levodopa should not be used in patients with the following conditions.
- Glaucoma (increased pressure in the eye)
- Liver problems
- Kidney problems
- Heart problems
- Hyperthyroidism (overactive thyroid)
- Severe mental illness
- Skin cancer
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid consumption of alcohol while taking Benserazide+levodopa as it may lead to increased dizziness and drowsiness.
Pregnancy
safe if prescribedBenserazide+levodopa should not be taken by pregnant women as it may cause harmful effects to the unborn baby. Consult your doctor for further advice.
Breast Feeding
cautionBenserazide+levodopa may cause harmful effects to the nursing baby when used by breastfeeding mothers. It is used only if the physician believes the benefits outweigh the risks.
Driving
unsafeBenserazide+levodopa may cause a sudden onset of sleepiness. It is advised against driving or operating heavy machinery while using Benserazide+levodopa.
Liver
cautionBenserazide+levodopa should be used with caution if you have a history of liver diseases. The dose may be adjusted by your doctor as required.
Kidney
cautionBenserazide+levodopa should be used with caution if you have a history of kidney diseases. The dose may be adjusted by your doctor as required.
Children
unsafeBenserazide+levodopa is not recommended for children as the safety and efficacy have not established.
Habit Forming
Diet & Lifestyle Advise
Diet:
- Limit high-protein foods as they may interfere with the action of medicine.
- Choose whole-grain foods like whole-wheat bread, oats, brown rice, or pasta.
- Eat balanced meals at regular times.
Digestive Health:
- Include fibre-rich foods such as fruits, vegetables, and whole grains.
- Fibre helps reduce constipation and supports gut comfort.
Fluids:
- Drink enough water throughout the day to prevent dehydration.
- Proper hydration helps reduce headaches and tiredness.
Daily Habits:
- Avoid alcohol, as it can increase sleepiness.
- Maintain a regular meal and sleep routine to support overall well-being
Special Advise
- Do not discontinue treatment abruptly without discussing it with your doctor, as Benserazide+levodopa may cause withdrawal symptoms such as confusion, muscle stiffness, and changes in heartbeat and breathing.
- Let your doctor know that you are taking Benserazide+levodopa before undergoing any laboratory tests, as it may affect some test results. In addition, it needs to be stopped before undergoing surgery or before taking a general anaesthetic.
- Use reliable and effective contraception while using this medicine to prevent pregnancy.
Patients Concern
Disease/Condition Glossary
Parkinson’s disease (PD): It is also known as a movement disorder that mainly affects a person's ability to perform regular activities. It is a chronic (long-term) and progressive disorder that can worsen with time if proper treatment is not provided at the right time. Common symptoms include tremors at rest, limb stiffness, slowness of movement, difficulty with movement or walking, and impaired balance. Other motor symptoms include difficulty solving problems, small handwriting, and a stooped posture. This disease also affects the brain's ability to work correctly, such as sleep disturbances, reduced ability to smell, depression, fatigue, and anxiety. However, the symptoms of this disease vary from person to person. There are specific neurons present in the brain that are responsible for making dopamine. This neurotransmitter helps regulate body movement. Loss of dopamine is supposed to be the primary reason for the occurrence of Parkinson's disease. Treatment with medications and physiotherapy may help control symptoms and improve quality of life for as long as possible.
FAQs
Benserazide+levodopa is used to treat Parkinson's disease, a disorder of the central nervous system that affects movement and locomotion.
Benserazide+levodopa contains Levodopa and Benserazide, which is used to treat Parkinson's disease. Levodopa works by increasing dopamine levels, a chemical messenger present in the brain that causes symptoms of Parkinson's disease. Benserazide prevents the breakdown of Levodopa, thereby improving its efficacy.
Benserazide+levodopa can cause drowsiness. Some patients taking this medicine may also experience a sudden onset of sleepiness without any warning signs. So, it would be best if you refrained from activities that require you to stay alert, such as driving or operating heavy machinery.
Benserazide+levodopa may alter the test results of some blood or urine tests. It is essential to inform your doctor before undergoing any laboratory tests.
Benserazide+levodopa is not recommended for patients with glaucoma (optic nerve damage due to increased intraocular pressure) because it may increase intraocular pressure.
Inform your doctor if you notice any impulsive behaviours such as the urge to eat, gamble, spend money, or increased sexual desire. Benserazide+levodopa may cause drowsiness, so do not drive or operate heavy machinery.
The effects of Benserazide+levodopa on bones with long-term use are not known. There is no clear evidence that Benserazide+levodopa directly affects bones. Please consult a doctor if you have any concerns or require personalised advice.
Benserazide+levodopa causes side effects such as nausea, vomiting, loss of appetite, diarrhoea, irregular heartbeat, weight gain, constipation, skin rashes, confusion, tiredness, and anemia (low number of red blood cells). Please consult a physician immediately if any of these side effects persist.
