If you have a predisposition to hypotension, aspiration pneumonia, or severe hepatic or cardiac impairment, you should use BLONANSERIN with caution. If you have had suicidal thoughts in the past, tell your doctor. If you are pregnant or breastfeeding, do not take BLONANSERIN unless your doctor tells you to. As BLONANSERIN may cause drowsiness and restlessness, do not drive or operate machinery unless you are alert. Keep your doctor updated about your medications and medical condition to rule out potential interactions and negative effects.

Drug-Drug Interactions: BLONANSERIN may interact with anti-epileptics (carbamazepine), anti-fungal (ketoconazole), medications used to treat obsessive-compulsive disorder (fluvoxamine), anti-depressants (fluoxetine, nefazodone) and medicines used to treat Parkinson's disease (levodopa, dopamine).

Drug-Food Interactions: No interactions found or established.

Drug-Disease Interactions: Inform your doctor if you have liver disorders, hepatic disorders, cardiac disorders, hypertension, seizures, diabetes, lipid alterations, weight gain, parkinsonism, obesity, dyslipidemia, or high cholesterol levels.

• Eat a healthy diet and exercise on a regular basis.
• Attend therapy regularly.
• Practice meditation and yoga.
• Maintain a consistent sleep schedule.
• Avoid smoking and drinking alcohol.
• Learn about your condition, be aware of the risk factors, and stick to your doctor's treatment plan.

• When taking a BLONANSERIN, you may become more susceptible to severe temperature circumstances (such as too hot or too cold) when taking BLONANSERIN; thus, it is best to avoid being too cold/hot or dehydrated, especially during the summer. To cope with this, drink enough fluids and water.