About CEFTRIAXONE+VANCOMYCIN
CEFTRIAXONE+VANCOMYCIN belongs to the group of medicines called antibiotics. It is used to treat various bacterial infections in the body. A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection.
CEFTRIAXONE+VANCOMYCIN contains Ceftriaxone (third-generation cephalosporin antibiotic) and Vancomycin (a tricyclic glycopeptide antibiotic). Together, Ceftriaxone and vancomycin work by interfering with the formation of the bacterial cell wall (a protective covering) necessary for their survival. Thereby damaging the bacterial cell wall and killing bacteria. Thus, CEFTRIAXONE+VANCOMYCIN helps in treating bacterial infection.
CEFTRIAXONE+VANCOMYCIN will be administered by a healthcare professional; do not self-administer. In some cases, CEFTRIAXONE+VANCOMYCIN may cause injection site reactions, diarrhoea, rashes, changes in results of blood and liver tests, abdominal pain, nausea, abnormalities in the number of white blood cells and platelets, and low potassium levels. Most of these side effects of CEFTRIAXONE+VANCOMYCIN do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.
Let your doctor know about your medical and medication history to avoid the occurrence of potential interactions. CEFTRIAXONE+VANCOMYCIN should only be given during pregnancy when the need has been established. Hence, inform your doctor if you are pregnant, suspect you are pregnant or plan to have a baby; your doctor will weigh the benefits of CEFTRIAXONE+VANCOMYCIN therapy against the risk to your baby. Breastfeeding should be avoided unless instructed by the doctor. Consumption of alcohol should be avoided while on treatment with CEFTRIAXONE+VANCOMYCIN.
Uses of CEFTRIAXONE+VANCOMYCIN
Bacterial infections
Medicinal Benefits
Ceftriaxone and Vancomycin are both present in CEFTRIAXONE+VANCOMYCIN. Vancomycin is a tricyclic glycopeptide antibiotic, whereas Ceftriaxone is a third-generation cephalosporin antibiotic. Ceftriaxone and Vancomycin have been shown to be effective in treating a variety of bacterial infections while having no adverse effects on the liver or kidney. The medicine was well tolerated by the patients, with no serious side effects.
Directions for Use
Storage
Side Effects of CEFTRIAXONE+VANCOMYCIN
- Injection site reactions
- Diarrhoea
- Rashes
- Changes in results of blood and liver tests
- Abdominal pain
- Nausea
- Abnormalities in the number of white blood cells and platelets
- Low potassium levels
In-Depth Precautions and Warning
Drug Warnings
If you are pregnant or breastfeeding, discuss with your doctor about the risks and benefits before taking CEFTRIAXONE+VANCOMYCIN. For effective outcomes, it is recommended that you complete the entire course of CEFTRIAXONE+VANCOMYCIN as prescribed by your doctor. If you are receiving or scheduled for vaccines, inform your doctor before receiving CEFTRIAXONE+VANCOMYCIN. CEFTRIAXONE+VANCOMYCIN should be used cautiously in people with Clostridium difficile-associated diarrhoea and hyperbilirubinemia (too much bilirubin in blood). It is recommended not to use if you are allergic to any component in CEFTRIAXONE+VANCOMYCIN. So, before taking CEFTRIAXONE+VANCOMYCIN, inform your doctor about all of your medical problems, sensitivities, and medications.
Drug Interactions
Drug-Drug Interactions: CEFTRIAXONE+VANCOMYCIN may interact with folic acid analogues (e.g. leucovorin, levoleucovorin), immunosuppressive medications (e.g. Mycophenolate mofetil, mycophenolic acid), antiviral medications (e.g. adefovir) and certain vaccinations (BCG vaccine, Cholera vaccine live, Typhoid vaccine live).
Drug-Food Interactions: Alcohol consumption should be avoided.
Drug-Disease Interactions: CEFTRIAXONE+VANCOMYCIN may interact with certain disease conditions, including colitis (inflammation in your colon), hearing loss, tinnitus, kidney dysfunction, liver disease, biliary obstruction, pancreatitis, vitamin k deficiency, prothrombin time alterations, and seizers. So, inform your doctor about your medical conditions before taking CEFTRIAXONE+VANCOMYCIN.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAvoid taking alcohol while using CEFTRIAXONE+VANCOMYCIN since it may worsen the disease condition.
Pregnancy
cautionCEFTRIAXONE+VANCOMYCIN should not be used during pregnancy unless clearly necessary. So, inform your doctor if you are pregnant or suspect pregnancy. Your doctor will weigh the benefits and potential risks before prescribing CEFTRIAXONE+VANCOMYCIN.
Breast Feeding
cautionInform the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or the medicine, considering the importance of the medicine to the mother.
Driving
safeCEFTRIAXONE+VANCOMYCIN will not affect your ability to drive or operate machinery. However, do not drive or operate machinery if you feel sleepy or dizzy after taking medicine.
Liver
cautionCaution should be exercised while using CEFTRIAXONE+VANCOMYCIN in patients with liver disease. Inform your doctor before receiving CEFTRIAXONE+VANCOMYCIN if you have a history of liver diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionCaution should be exercised while using CEFTRIAXONE+VANCOMYCIN in patients with kidney disease. Inform your doctor before receiving CEFTRIAXONE+VANCOMYCIN if you have a history of kidney diseases/conditions. Your doctor will prescribe only if the benefits outweigh the risks.
Children
cautionSafety and effectiveness of CEFTRIAXONE+VANCOMYCIN in patients below 18 years of age have not been established.
Habit Forming
Diet & Lifestyle Advise
- Probiotics should be taken after taking the full course of CEFTRIAXONE+VANCOMYCIN to restore healthy bacteria that may have been killed in the intestine. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut, kombucha, and kimchi can help restore the intestine's good bacteria.
- Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria, which helps stimulate their growth. Whole grains like whole-grain bread and brown rice should be included in your diet.
- Avoid intake of alcoholic beverages with CEFTRIAXONE+VANCOMYCIN as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid CEFTRIAXONE+VANCOMYCIN in fighting off infections.
Special Advise
Patients Concern
Disease/Condition Glossary
Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. Infectious or harmful bacteria can make you sick and reproduce quickly in the body. These harmful bacteria produce toxins, which can damage tissue and make you sick. It can target any body part and multiply very quickly. When infected with bacteria, you can experience generalized symptoms like fever, chills, and fatigue. Anyone can become infected with a bacterial infection. However, people with weak immune systems or taking immunosuppressive medicine are more prone to bacterial infection.
