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About CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE

CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE belongs to the class of 'gastrointestinal agents,' primarily used to treat stomach and intestinal disorders, such as irritable bowel syndrome, peptic ulcers, enterocolitis (swelling in the intestine), and bowel infections. Irritable bowel syndrome is an intestinal disorder that causes stomach pain, wind, constipation, and diarrhea. Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining.

CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE contains Chlordiazepoxide (benzodiazepine), Clidinium (anti-cholinergic), and Pantoprazole (proton pump inhibitor (PPI)). Chlordiazepoxide decreases abnormal and excess activity of the nerve cells in the brain by increasing a chemical messenger called GABA (gamma-aminobutyric acid). Clidinium helps relax the smooth muscles and inhibits the natural gut movements, thereby providing relief from cramps, discomfort, bloating, and pain. Pantoprazole works by blocking an enzyme called gastric proton pump, which is responsible for acid production.

Your doctor will advise the appropriate dose that suits your medical condition. Common side effects of CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE include dizziness, drowsiness, weakness, blurred vision, dry eyes, dry mouth, nausea, constipation, flatulence, confusion, diarrhea, and abdominal bloating. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.

Before using CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE, let your doctor know if you have any liver, kidney, heart diseases, or other medical history. CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE may cause blurred vision, dizziness, and drowsiness; hence do not drive or operate machinery until you feel better. Avoid taking CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE if you are pregnant or planning for pregnancy as it may cause congenital disabilities (birth defects). CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE may pass into breastmilk, so avoid taking CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE if you are breastfeeding. Avoid consumption of alcohol while taking CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE as it may cause increased drowsiness. CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE is not recommended for use in children.

Uses of CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE

Irritable bowel syndrome (IBS), Peptic ulcers, Enterocolitis 

Medicinal Benefits

CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE is a combination of Chlordiazepoxide, Clidinium, and Pantoprazole. Chlordiazepoxide is a benzodiazepine that decreases abnormal and excess activity of the nerve cells in the brain by increasing a chemical messenger called GABA (gamma-aminobutyric acid). Clidinium is an anticholinergic agent that blocks acetylcholine activity by binding to muscarinic receptors on smooth muscle. This helps relax the smooth muscles and inhibits the natural gut movements, thereby providing relief from cramps, discomfort, bloating, and pain. Pantoprazole is a proton pump inhibitor (PPI) that works by blocking an enzyme called gastric proton pump, which is responsible for acid production. CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE is also used to relieve stomach cramps, bloating, and pain in the stomach and intestine.

Directions for Use

Swallow it as a whole with a glass of water. You can take it with or without food at regular intervals, as prescribed by the doctor. Do not crush, chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE

  • Dizziness
  • Drowsiness
  • Weakness
  • Blurred vision
  • Dry eyes
  • Dry mouth
  • Nausea
  • Constipation
  • Flatulence
  • Confusion
  • Diarrhea
  • Abdominal bloating

In-Depth Precautions and Warning

Drug Warnings

Let your doctor know if you are sensitive to CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE or its components. CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE should be used with caution and only under doctor's supervision if you have glaucoma, enlarged prostate, bladder neck obstruction, vision problems, urination problems, depression, liver and kidney problems; if you are 65years or older; if you use opioid (narcotic) medicines, such as codeine, hydrocodone, hydromorphone, methadone, morphine, oxycodone, and tramadol. CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE may be habit-forming, so inform your doctor if you have a history of drug addiction or abuse. Avoid taking CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE if you are pregnant or planning for pregnancy as it may cause congenital disabilities (birth defects). CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE can pass into the breast milk and may affect your infant. Hence, it is not recommended to use CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE during breastfeeding. CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE may cause blurry vision and sleepiness affecting your mental focus; hence do not drive or operate machinery until you feel better. Avoid consumption of alcohol while taking CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE as it may cause increased drowsiness. CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE should not be given to children as the safety and effectiveness were not established.

Drug Interactions

Drug-Drug Interaction: CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE may interact with antacids, blood thinners (warfarin), antipsychotic medications (chlorpromazine, fluphenazine, and thioridazine), and antidepressants (isocarboxazid, linezolid, methylene blue, phenelzine, selegiline, tranylcypromine).

Drug-Food Interaction: Avoid fatty foods, alcohol, caffeine and other triggering foods that can worsen your IBS.

Drug-Disease Interaction: Brief your doctor if you have a medical history of glaucoma (increased pressure in the eye), prostatic hypertrophy (an enlarged prostate), bladder neck obstruction (a blockage of your bladder that causes problems with urination), liver, and kidney problems.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • CHLORPROMAZINE
  • FLUPHENAZINE
  • THIORIDAZINE
  • ISOCARBOXAZID
  • LINEZOLID
  • METHYLENE BLUE
  • PHENELZINE
  • SELEGILINE
  • TRANYLCYPROMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      It is advised to avoid alcohol intake since it may increase dizziness and drowsiness.

    • Safety Warning

      Pregnancy

      unsafe

      CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE is not recommended for use during pregnancy since it may cause birth defects. It is advised to consult your doctor if you plan to conceive or already pregnant before starting CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE.

    • Safety Warning

      Breast Feeding

      unsafe

      It is not recommended to use CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE during breastfeeding. CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE can pass into breast milk and may affect the baby. Please consult your doctor before taking CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE if you are a nursing mother.

    • Safety Warning

      Driving

      unsafe

      CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE may cause side effects like dizziness, drowsiness, and blurry vision, which could affect your ability to focus. Please do not drive or operate machines until you feel better.

    • Safety Warning

      Liver

      caution

      Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE.

    • Safety Warning

      Kidney

      caution

      Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE.

    • Safety Warning

      Children

      unsafe

      CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE is not recommended for children as the safety and effectiveness were not established.

    Habit Forming

    Yes

    Diet & Lifestyle Advise

    • Avoid or limit the intake of alcohol and caffeine.
    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.
    • Limit taking high-fiber foods, foods, and drinks containing chocolate, alcohol, caffeine, fructose, sorbitol, carbonated drinks, fried, and fatty foods. 
    • Do not have large meals at a time. Instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
    • Practice yoga and recreation techniques to manage your emotional stress.
    • If you are lactose intolerant, avoid using dairy products since it can worsen your IBS.
    • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
    • Drink plenty of fluids and dress lightly to prevent heatstroke and dehydration.
    • Avoid overly sweating activities like hard exercises and using hot tubs.

    Special Advise

    • It is advised to monitor your blood pressure and blood glucose levels regularly while using CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE.
    • Please do not stop taking CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE on your own as it may cause withdrawal symptoms.
    • Your doctor may suggest diagnostic procedures like endoscopy or colonoscopy to understand your disease and its severity.

    Patients Concern

    Disease/Condition Glossary

    Irritable Bowel Syndrome (IBS): It is also termed IBS colitis, mucous colitis, spastic colon, nervous colon, and spastic bowel. It is an inflammatory bowel disease that affects the large intestine. Symptoms of an IBS include abdominal pain, bloating, diarrhea, mucus in stools, wind, constipation, tiredness, anxiety, depression, heartburn, indigestion, and headaches. IBS can be controlled by managing diet, excluding certain intolerant foods, lifestyle, and stress. It is more commonly found in people in their late teens to early 40s.

    Peptic ulcers: Peptic ulcers are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion. 

    Enterocolitis: It is an inflammation of the digestive tract caused by bacteria, viruses, parasites, fungus, or other causes. Symptoms include abdominal pain, nausea, vomiting, mucus-like discharge from the rectum, loss of appetite, and diarrhea. 

    FAQs

    How does CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE work?

    CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE consists of Chlordiazepoxide, Clidinium, and Pantoprazole. Chlordiazepoxide decreases abnormal activity in the brain and relaxes gastrointestinal muscles. It also reduces anxiety associated with gastrointestinal disorders. Clidinium works by reducing stomach acid and decreases stomach spasms and cramps. Pantoprazole reduces acid production. Collectively, CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE helps treat stomach and intestinal disorders.

    Does CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE cause constipation?

    Constipation might be a side-effect of CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE. Drink enough fluids and eat fiber rich food if you experience constipation. Consult your doctor if you experience excess constipation.

    Is CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE habit-forming?

    CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE contains chlordiazepoxide, which is a habit-forming drug. This could occur especially in people with a history of drug addiction or abuse and in those who are alcoholics. Take CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE only as prescribed by the doctor and do not exceed the dose and duration.

    Do I need to avoid any foods if I am suffering from IBS?

    If you suffer from IBS, limit taking high fiber foods, foods, and drinks containing chocolate, alcohol, caffeine, fructose, sorbitol, carbonated drinks, fried, and fatty foods. Do not have large meals; instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.

    Does CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE cause dry mouth?

    Dry mouth could be a side-effect of CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

    Available Medicines for

    CHLORDIAZEPOXIDE+CLIDINIUM+PANTOPRAZOLE