About CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE
CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE belongs to a class of medications called ‘expectorants’ primarily used to treat dry cough. Additionally, CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE also treats allergy symptoms such as sneezing, runny nose, throat irritation or watery eyes. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways.
CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE is a combination of four drugs, namely: Guaiphenesin (expectorant), Dextromethorphan hydrobromide (cough suppressant), Phenylephrine hydrochloride (decongestant) and Chlorpheniramine maleate (antihistamine). Guaiphenesin belongs to the expectorant class that increases the volume of fluid in the airways, reduces the stickiness of mucus, and removes it from the airways. Dextromethorphan hydrobromide is a cough suppressant that works by blocking the transmission of nerve signals from the cough centre in the brain to the muscles that produce cough. Thus, it decreases the need to cough. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thereby providing relief from congestion and decreasing mucus production. Chlorpheniramine maleate belongs to the class of antihistamines (anti-allergic drugs) that works by blocking the action of histamine, a substance responsible for causing allergic reactions.
Take CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE with or without food as advised by your doctor with the help of a measuring cup. Your doctor will recommend how often you take CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE based on your medical condition. Some people may experience nausea, stomach upset, vomiting, loss of appetite, drowsiness, headache, diarrhoea, dizziness or skin rash. Most of these side effects of CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Please tell your doctor if you are allergic to CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE. Drink plenty of fluids while taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE to loosen the congestion. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath) or chronic obstructive pulmonary disease (COPD) inform your doctor before taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE.
Uses of CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE
Dry cough
Medicinal Benefits
CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE contains Guaiphenesin, Dextromethorphan hydrobromide, Phenylephrine hydrochloride, and Chlorpheniramine maleate used to treat dry cough. Guaiphenesin is an expectorant that increases the volume of fluid in the airways, reduces the stickiness of mucus, and removes it from the airways. Dextromethorphan hydrobromide is a cough suppressant that works by blocking the transmission of nerve signals from the cough center in the brain to the muscles that produce cough. Thus, it decreases the need to cough. Phenylephrine hydrochloride is a decongestant that works by contracting and narrowing the blood vessels. Thus, provides relief from congestion and decreases mucus production. Chlorpheniramine maleate is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness.
Directions for Use
Storage
Side Effects of CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE
- Nausea
- Stomach upset
- Vomiting
- Loss of appetite
- Drowsiness
- Headache
- Diarrhoea
- Dizziness
- Skin rash
In-Depth Precautions and Warning
Drug Warnings
Please inform your doctor if you are allergic to CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE. If you are about to undergo any medical tests or surgery, please inform your doctor that you are taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE. Avoid using CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumour in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE.
Drug Interactions
Drug-Drug Interaction: CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE may have interaction with anti-allergic drugs (diphenhydramine, cetirizine), antidepressants (duloxetine, sertraline, escitalopram), narcotic analgesics (hydrocodone, codeine), antianxiety drug (alprazolam), central nervous system stimulants (methylphenidate), antipsychotics (quetiapine), medicines used to treat irregular heartbeats (quinidine), anticonvulsants (pregabalin), a central nervous system stimulant (amphetamine).
Drug-Food Interaction: Avoid or limit the intake of chocolate and caffeine-containing foods such as cocoa beans and tea leaves with CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE as they may increase the risk of severity of side effects. Also, avoid consumption of alcohol with CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE as it may increase the risk of adverse effects such as drowsiness, dizziness, or difficulty in concentrating.
Drug-Disease Interaction: If you have high blood pressure, fits, glaucoma, hyperthyroidism (overactive thyroid), chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE as it may increase adverse effects. Please consult a doctor before consuming alcohol with CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE.
Pregnancy
cautionPlease consult a doctor if you are pregnant. CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE is given to pregnant women only if the doctor thinks the benefits outweigh the risks.
Breast Feeding
cautionIt is unknown whether CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE is excreted in human milk. CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.
Driving
cautionCHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE may impair thinking or cause blurred vision in some people. Therefore, drive only if you are alert after taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE.
Liver
cautionTake CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE with caution, especially if you have a history of liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE with caution, especially if you have a history of kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
consult your doctorPlease consult your doctor. Your doctor may prescribe a suitable dose based on your child's age, body weight and condition.
Habit Forming
Diet & Lifestyle Advise
- Avoid dairy products such as milk as they may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Instead, replace baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips with green leafy vegetables.
- Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
- Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content, such as pears, watermelon, peaches and pineapples.
Special Advise
- You are recommended to inform your doctor that you are taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE before undergoing any medical tests or surgery.
- Drink plenty of fluids while taking CHLORPHENIRAMINE MALEATE+DEXTROMETHORPHAN HYDROBROMIDE+GUAIPHENESIN+PHENYLEPHRINE HYDROCHLORIDE to loosen the congestion of nasal passage and airways. If you are a kidney patient, ask a doctor before taking fluid.
Patients Concern
Disease/Condition Glossary
Cough: Coughing is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus, and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, it indicates you may have allergies or a minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection.
Allergies: These occur when foreign elements known as allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger, 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.
