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About CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE

CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE belongs to the class of medications called ‘expectorants’ used to treat cough. Cough is a common reflex action to clear foreign particles, mucus or irritants present in the airway. CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE also treats symptoms such as runny nose, throat or airway irritation, sinus pressure or congestion, watery, or itchy eyes and sneezing associated with upper respiratory tract infections. 

CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE is a combination of six medicines: Chlorpheniramine, Dextromethorphan, Guaifenesin, Sodium citrate, Menthol, and Ammonium chloride. Chlorpheniramine is an antihistamine and works by blocking histamine, a substance responsible for causing allergic reactions.  Dextromethorphan acts as a cough suppressant by blocking nerve signals transmitted from the cough centre in the brain. Guaifenesin and ammonium chloride work by  helping in the removal of mucus (phlegm) from the airways . Sodium citrate is a 'mucolytic agent' that makes sputum less viscous and easier to cough out. Menthol is an organic compound that produces a cooling sensation and relieves throat irritation. Thus, together CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE helps to relieve overall cough, cold and allergic symptoms. 

You should take this medicine as prescribed by your doctor. However, CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE is usually prescribed for short-term use (not more than 7 days). The common side-effects of CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE are dry mouth, nausea, stomach upset, vomiting, drowsiness, headache, blurred vision, constipation, dizziness and restlessness. These side-effects usually do not require any medical attention. However, consult a doctor immediately if any of these side-effects persist or worsen. 

Do not take CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE if you are allergic to any contents of it. CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE is not recommended for treating the chronic cough associated with smoking, or lung problems such as asthma, chronic obstructive pulmonary disease (COPD) or emphysema. It is also used with caution in patients diagnosed with high blood pressure, epilepsy (fits), glaucoma (a condition caused by increased pressure inside the eye), urination problems and phenylketonuria (a congenital disability resulting in accumulation of phenylalanine (amino acid) in the body). Please do not take this medication with alcohol or sedatives, hypnotics or tranquillizers as it increases the risk of side-effects. It is also not recommended for use in children below 2 years of age. It is also used with caution in pregnant and breastfeeding women. 

Uses of CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE

Cough

Medicinal Benefits

CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE is a combination of six medicines: Chlorpheniramine, Dextromethorphan, Guaifenesin, Sodium citrate, Menthol, and Ammonium chloride. It is used in the treatment of cough. Chlorpheniramine inhibits the action of histamines (a substance that causes allergic reactions).  Dextromethorphan acts on the cough centre in the brain and blocks the nerve signals that cause cough. Guaifenesin and ammonium chloride help in the removal of mucus (phlegm) from the airways. Sodium citrate helps loosen and thin the sputum in the airway to cough up the mucus easily. Menthol provides a cooling sensation and relieves throat irritation.  Thus, together CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE helps to relieve overall cough, cold, and allergic symptoms.

Directions for Use

Syrup: Shake the bottle well before each use. Take the prescribed dose of liquid medicine with a marked measuring spoon, oral syringe or medicine cup. Do not use any household spoon to measure the syrup. You can take this medicine with or without food.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE

  • Dry mouth
  • Nausea (feeling sick)
  • Stomach upset
  • Vomiting (being sick)
  • Drowsiness
  • Headache
  • Blurred vision
  • Constipation
  • Dizziness
  • Restlessness

In-Depth Precautions and Warning

Drug Warnings

Many combination medicines contain guaifenesin, ammonium chloride, and sodium citrate. So, always inform your doctor that you are taking CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE to avoid overdosing of these drugs. CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE may cause drowsiness, so avoid taking this medicine with other sedatives or medications used to treat depression, psychosis, or behavioral problems. Do not use this medicine for longer duration than recommended. Stop using CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE and consult a doctor if your symptoms does not improve or have fever, rash, or persistent headache within 7 days after using this medicine. 

Drug Interactions

Drug-Drug Interactions: CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE may interact with anti-allergic drugs (diphenhydramine and cetirizine), antidepressants (duloxetine, sertraline, and escitalopram), narcotic analgesic (codeine), opioid (methadone), antipsychotics (haloperidol and quetiapine), antifungal medication (terbinafine), antianxiety drug (alprazolam, clonazepam, and diazepam), medicines used to treat irregular heartbeat (quinidine and amiodarone), anticonvulsants (pregabalin), and a central nervous system stimulant (amphetamine).

Drug-Food Interactions: Alcohol may increase the risk of side-effects such as drowsiness or dizziness.

Drug-Disease Interactions: CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE should be used with caution in conditions such as asthma, chronic obstructive pulmonary disease (COPD), or emphysema, high blood pressure (hypertension), epilepsy (fits), glaucoma (a condition caused by increased pressure inside the eye), liver diseases, and phenylketonuria (a birth defect resulting in accumulation of phenylalanine (amino acid) in the body).

Drug-Drug Interactions Checker List:

  • DIPHENHYDRAMINE
  • CETIRIZINE
  • DULOXETINE
  • SERTRALINE
  • ESCITALOPRAM
  • CODEINE
  • HALOPERIDOL
  • QUETIAPINE
  • ALPRAZOLAM
  • CLONAZEPAM
  • DIAZEPAM
  • QUINIDINE
  • AMIODARONE
  • PREGABALIN
  • AMPHETAMINE
  • TERBINAFINE
  • METHADONE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Alcohol may increase the risk of side-effects and worsen the condition.

    • Safety Warning

      Pregnancy

      unsafe

      CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE is a category C drug. CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE should not be used in pregnant women as it may cause harmful effects to unborn baby.

    • Safety Warning

      Breast Feeding

      caution

      CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE should be used with caution in breastfeeding mothers.

    • Safety Warning

      Driving

      caution

      CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE may cause drowsiness. So, do not drive or operate heavy machinery while using CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE.

    • Safety Warning

      Liver

      caution

      CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE should be used with caution in patients with liver diseases. Dose adjustments may be necessary.

    • Safety Warning

      Kidney

      caution

      CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE should be used with caution in patients with kidney diseases. Dose adjustments may be necessary.

    • Safety Warning

      Children

      caution

      CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE should be used with caution in children below 12 years. Dose adjustments may be necessary.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods to have relief from cough. Avoid taking baked foods, fried foods, white bread, white pasta, French fries, sugary desserts and chips. Opt for green leafy vegetables.
    • Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
    • Avoid citrus fruits as it may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

    Special Advise

    • You are recommended to inform your doctor that you are taking CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE before undergoing any medical tests or surgery.
    • It is advised to stop the use of CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE if your cough persists for more than 1 week and it reoccurs or is accompanied by hay fever, skin rash or persistent fever. In such cases, consult a doctor immediately. 

    Patients Concern

    Disease/Condition Glossary

    Cough: Coughing is a reflex action or body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, it indicates you may have allergies or minor infection in the respiratory tract, and yellow or green mucus indicates a respiratory infection. 

    FAQs

    How does CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE work?

    CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE is used in the treatment of cough. Chlorpheniramine inhibits the action of histamines (a substance that causes allergic reactions).  Dextromethorphan acts on the cough centre in the brain and blocks the nerve signals that cause cough. Guaifenesin and ammonium chloride help in the removal of mucus (phlegm) from the airways. Sodium citrate helps loosen and thin the sputum in the airway to cough up the mucus easily. Menthol provides a cooling sensation and relieves throat irritation.

    What precautions should I take to reduce cough?

    It is advised to take plenty of fluids when you have a cough or cold as it helps to loosen up mucus in the airway. It also helps to lubricate the throat and reduce throat irritation.

    What are the side-effects of CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE?

    The common side-effects of CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE are dry mouth, nausea, stomach upset, vomiting, drowsiness, headache, blurred vision, constipation, dizziness, and restlessness. These side-effects usually go away without any treatment. However, seek medical attention if any of these side-effects persist.

    Can CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE be given to treat all types of cough?

    CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE should not be given to treat cough associated with smoking, or lower respiratory tract infections such as bronchitis (inflammation of the bronchi), asthma, chronic obstructive pulmonary disease (COPD) and pneumonia.

    Can I use CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE as a sleeping aid?

    CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE is recommended for the treatment of cough. So, it is not advised to use this medicine for other conditions. Please speak to your doctor about the benefits and risks associated with this medicine before using it for any illness.

    Why is cough worse at night?

    The mucus starts accumulating at the back of the throat when you lie down and trigger a cough. So, it is advised to incline the head of your bed and use a humidifier while sleeping to reduce cough.

    Available Medicines for

    CHLORPHENIRAMINE+DEXTROMETHORPHAN+GUAIFENESIN+SODIUM CITRATE+MENTHOL+AMMONIUM CHLORIDE