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About CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL

CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL belongs to a group of medications called ‘antipsychotics’. It is used in the treatment of schizophrenia or psychosis. Schizophrenia is characterized by hallucinations symptoms (seeing or hearing things that are not real) and delusions (wrong beliefs). Manic episodes of excitement or depression characterize bipolar disorder. CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL prevents the occurrence of these symptoms. 

CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL composed of three medications namely Chlorpromazine, Trifluoperazine,  and Trihexyphenidyl. Chlorpromazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Trihexyphenidyl is an anticholinergic that works on the nervous system and corrects some of the side effects occurring during antipsychotic treatment. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Take CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL as prescribed by your doctor. You are advised to take CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side effects such as nausea, constipation, sedation, dryness in the mouth, weight gain, orthostatic hypotension (sudden lowering of blood pressure on standing), urinary retention, the Increased prolactin level in blood, dizziness, blurred vision, nervousness. Most of these side effects of CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

Do not take CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL if you are allergic to CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL or any other ingredients present in it. Before taking CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL, talk to your doctor if you or your family have a history of hypertension, CNS depression, narrow-angle glaucoma, neuroleptic malignant syndrome, tardive dyskinesia,  and have a history of dementia (memory loss). CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL. Please do not stop taking CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL without your doctor’s advice as it may lead to withdrawal symptoms.
 

Uses of CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL

Schizophrenia, Parkinson's disease.

Medicinal Benefits

CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL composed of three medications namely Chlorpromazine, Trifluoperazine,  and Trihexyphenidyl belongs to a group of medications called ‘antipsychotics’. It is used in the treatment of schizophrenia or psychosis. Chlorpromazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Trihexyphenidyl is an anticholinergic that works on the nervous system and corrects some of the side effects occurring during antipsychotic treatment. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

Directions for Use

Swallow it as a whole with a glass of water. Do not chew, crush or break it. CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL is to be taken with food.

Storage

Store in a cool and dry place away from sunlight

Side Effects of CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL

  • Nausea
  • Constipation
  • Sedation
  • Dryness in mouth
  • Weight gain
  • Orthostatic hypotension (sudden lowering of blood pressure on standing)
  • Urinary retention
  • The increased prolactin level in the blood
  • Dizziness
  • Blurred vision
  • Nervousness

In-Depth Precautions and Warning

Drug Warnings

Do not take CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL if you are allergic to CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL or any other ingredients present in it. Before taking CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL, talk to your doctor if you or your family have a history of hypertension, CNS depression, narrow-angle glaucoma, neuroleptic malignant syndrome, tardive dyskinesia,  and have a history of dementia (memory loss). CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL is not recommended during pregnancy as it may affect the unborn baby. Tell your doctor if you are breastfeeding before taking CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL. Please do not stop taking CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL without your doctor’s advice as it may lead to withdrawal symptoms. CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL used with caution in kidney disease, liver disease and urinary obstruction.

Drug Interactions

Drug-drug interactions: CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL may interact with some medications, including antidepressants (citalopram, escitalopram, bupropion), medicines for Parkinson’s disease (levodopa, phenelzine), antiepileptic ( carbamazepine, phenobarbital), medicines control heartbeat ( amiodarone, disopyramide, quinidine), medicines used to calm emotion and mental disorder (olanzapine, prochlorperazine) antihypertensive (clonidine, guanethidine, propranolol), antibiotic (moxifloxacin) and medication used to treat mental illness (lithium), antihistamines (such as cetirizine, diphenhydramine), corticosteroids (prednisone).

Drug-food interactions: CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL may interact with grapefruit and alcohol and increase the risk of side-effects.

Drug-disease interactions: CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL should be used with caution in patients with heart problems such as QT prolongation (heart rhythm problem), acute alcohol abuse, central nervous system (CNS) depression, dementia, stroke, seizures, kidney diseases, diabetes, tardive dyskinesia, neuroleptic malignant syndrome, and liver problems.

Drug-Drug Interactions Checker List:

  • CITALOPRAM
  • ESCITALOPRAM
  • BUPROPION
  • PHENELZINE
  • LEVODOPA
  • CARBAMAZEPINE
  • PHENYTOIN
  • AMIODARONE
  • DISOPYRAMIDE
  • QUINIDINE
  • OLANZAPINE
  • PROCHLORPERAZINE
  • CLONIDINE
  • GUANETHIDINE
  • PROPRANOLOL
  • MOXIFLOXACIN
  • LITHIUM
  • CETIRIZINE
  • DIPHENHYDRAMINE
  • PREDNISONE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Alcohol may worsen the condition and increase the risk of side-effects while using CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL.

    • Safety Warning

      Pregnancy

      caution

      CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine.

    • Safety Warning

      Breast Feeding

      caution

      CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking this medicine

    • Safety Warning

      Driving

      caution

      CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL may cause especially to elderly patients, become drowsy, dizzy, light-headed, clumsy, unsteady or less alert than normal. If you are affected, do not drive or operate dangerous machinery after taking CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL.

    • Safety Warning

      Liver

      caution

      CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL is used with caution in liver diseases. Please consult your doctor before taking CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL.

    • Safety Warning

      Kidney

      caution

      CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL is used with caution in kidney diseases. Please consult your doctor before taking CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL.

    • Safety Warning

      Children

      caution

      CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL is not recommended for children below 1 year of age. However, please consult a doctor before giving CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL to children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Monitor your mood. Keep track of your mood regularly, including factors such as sleep, medicine and activities that can impact your mood. 
    • Exercise daily. Exercise is nice to relieve tension. It can also avoid the weight gain that can be a side effect of your bipolar medication.
    • You may also practice calming techniques such as meditation and deep breathing exercises.
    • Get some normal sleep. Having enough sleep will help to stabilize your mood.
    • Eat a healthy diet. Certain foods may affect your mood more than others. Consider keeping a food log to track what you eat and how certain foods make you feel. Talk to your doctor or nutritionist about foods that may help stabilize your mood.
    • Stay optimistic. It will take time for your symptoms to improve after you start bipolar therapy, but you will feel relaxed knowing that you will get better and that the worst is most definitely behind you.
    • A person should take a healthy diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, plant-based oils and low-fat dairy products will help to keep a person in good health and avoid chances of nausea and vomiting.
    • One should avoid taking greasy or oily foods as this food triggers nausea and vomit.
    • Eat cool foods instead of hot and spicy foods.
    • Include clear broths, non-fat yoghurt, fruit juice, sherbet and sports drinks for fluid make up which has got lost due to vomiting.

    Special Advise

    • Do not stop CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL suddenly, because it may cause withdrawal symptoms. So please consult your doctor before taking CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL.

    Patients Concern

    Disease/Condition Glossary

    Schizophrenia (psychosis): It is a mental illness in which brain information processing is affected. Patients with schizophrenia develop symptoms such as hallucinations (see or hear unreal things), delusions (false beliefs) and become withdrawn from society. They lose the ability to differentiate reality from false beliefs. Schizophrenia and bipolar disorder may occur due to genetic factors, alcohol or drug abuse, mental trauma. Schizophrenia may also occur due to brain injuries or diseases.

    Parkinson's disease: Parkinson's disease is a progressive nervous system disorder that affects movement. Symptoms start gradually, sometimes starting with a barely noticeable tremor in just one hand. Tremors are common, but the disorder also commonly causes stiffness or slowing of movement.
     

    FAQs

    How does CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL work?

    CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL composed of three medications namely Chlorpromazine, Trifluoperazine,  and Trihexyphenidyl belongs to a group of medications called ‘antipsychotics’. It is used in the treatment of schizophrenia or psychosis. Chlorpromazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood. Trihexyphenidyl is an anticholinergic that works on the nervous system and corrects some of the side effects occurring during antipsychotic treatment. Trifluoperazine is a typical antipsychotic. It works by blocking the action of dopamine, a chemical messenger in the brain that affects thoughts and mood.

    What are the common side effects of CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL?

    CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL causes common side effects such as nausea, constipation, sedation, dryness in the mouth, weight gain, orthostatic hypotension (sudden lowering of blood pressure on standing), urinary retention, the Increased prolactin level in blood, dizziness, blurred vision, nervousness. Most of these side effects of CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.

    In what conditions should I avoid using CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL?

    CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL should be used with caution in hypertension, CNS depression, narrow-angle glaucoma, neuroleptic malignant syndrome, tardive dyskinesia,  and have a history of dementia (memory loss).

    Can I stop CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL suddenly?

    CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL cannot be stopped CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL suddenly, because CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL may cause withdrawal symptoms. So please consult your doctor before stopping CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL.

    Is CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL is safe to use in tardive dyskinesia?

    CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL is not recommended for use in patients with tardive dyskinesia which is an involuntary movement of the tongue, lips, and face unless the patient has concomitant Parkinson's disease due to the increased risk of worsening of the patient's condition. Appropriate dose adjustments or replacement with a suitable alternative may be required in some cases based on the clinical condition.

    Available Medicines for

    CHLORPROMAZINE+TRIFLUOPERAZINE+TRIHEXIPHENIDYL