About CLEBOPRIDE
CLEBOPRIDE is an antiemetic medicine. It is used in the prevention of nausea and vomiting associated with cancer chemotherapy. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the natural response to the body to discharge the stomach contents forcefully. CLEBOPRIDE is also used in the treatment of gastro-oesophageal reflux disease (GERD). Gastroesophageal reflux disease is a condition that occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.
CLEBOPRIDE contains Clebopride, which belongs to the class of prokinetic agents. It works by blocking the messages between the chemoreceptor trigger zone (CTZ) and the vomiting centre in the brain. As a result, CLEBOPRIDE prevents the sensation of nausea and vomiting caused by cancer chemotherapy.
CLEBOPRIDE may cause certain side effects like restlessness, fatigue, drowsiness, diarrhea, weakness, and lack of energy. Most of these side effects do not require medical attention and will resolve gradually over time. However, if it does not resolve, consult your doctor. CLEBOPRIDE should be taken as prescribed by your doctor. CLEBOPRIDE can be taken with or without food. The dose of the medicine will be decided by your doctor based on your condition.
CLEBOPRIDE should be avoided if you are allergic to it. Keep your doctor informed about your health condition, including complete medication and medical history, to rule out any possible side effects/interactions. Before administration, inform your doctor if you have any history of liver/kidney disease and gastrointestinal disorders. Let your doctor know if you are pregnant or breastfeeding before starting treatment with CLEBOPRIDE. Avoid driving vehicles or operating machines, as this medicine may make you feel dizzy. Drinking alcohol can increase dizziness and also cause gastric problems. Hence, avoid alcohol consumption and smoking.
Uses of CLEBOPRIDE
Nausea and Vomiting associated with chemotherapy.
Medicinal Benefits
CLEBOPRIDE contains Clebopride, which belongs to the class of prokinetic agents. It works by blocking the messages between the chemoreceptor trigger zone (CTZ) and the vomiting centre in the brain. As a result, CLEBOPRIDE prevents the sensation of nausea and vomiting caused by cancer chemotherapy.
Directions for Use
Storage
Side Effects of CLEBOPRIDE
- Diarrhoea
- Stomach upset
- Indigestion
- Restlessness
- Fatigue
- Weakness
- Lack of energy
- Dizziness
In-Depth Precautions and Warning
Drug Warnings
CLEBOPRIDE should be avoided if you are allergic to it. Keep your doctor informed about your health condition, including complete medication and medical history, to rule out any side effects/interactions. Before administration, inform your doctor if you have any history of liver/kidney disease and gastrointestinal disorders. Let your doctor know if you are pregnant or breastfeeding before starting treatment with CLEBOPRIDE. Avoid driving vehicles or operating machines, as this medicine may make you feel dizzy. Drinking alcohol can increase dizziness and also cause gastric problems. Hence, avoid alcohol consumption and smoking. It is unknown whether CLEBOPRIDE can be given to children. Hence, it should be given only upon a doctor’s prescription.
Drug Interactions
Drug-Drug Interactions: CLEBOPRIDE may interact with pain killers (aspirin, acetaminophen), antidepressants (duloxetine), antihistamine (diphenhydramine), anti-anxiety (alprazolam), anticonvulsant (pregabalin), antiparkinson (levodopa), anti-diabetic (insulin), narcotics and sleep medicines.
Drug-Food Interactions: Avoid alcohol consumption and smoking.
Drug-Disease Interactions: Inform your doctor before giving CLEBOPRIDE if your child has any history of kidney or liver disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption during the treatment, as it can cause serious side effects.
Pregnancy
cautionIf you are pregnant or planning pregnancy, inform your doctor before receiving CLEBOPRIDE. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Breast Feeding
cautionIf you are breastfeeding, inform your doctor before receiving CLEBOPRIDE. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
unsafeCLEBOPRIDE may cause dizziness and make you sleepy or drowsy. Hence, avoid driving or operation medicine while on treatment with CLEBOPRIDE.
Liver
cautionPlease consult your doctor if you have a liver impairment or if you have any concerns regarding this.
Kidney
cautionPlease consult your doctor if you have a kidney impairment or if you have any concerns regarding this.
Children
consult your doctorPlease consult your doctor about using CLEBOPRIDE in children.
Habit Forming
Diet & Lifestyle Advise
- Certain food items/medicines are known to cause nausea/vomiting.
- Make sure to drink more fluids to avoid dehydration.
- Try to eat a healthy diet that includes lots of fruits and vegetables, nuts, and low-fat dairy products. It will help keep your child in good health and avoid nausea and vomiting.
- Avoid giving greasy or oily foods, as these foods trigger nausea and vomiting.
- Take sufficient rest and avoid any activity immediately after eating.
- Consume plain, light foods such as bread and biscuits.
- Avoid food with strong flavours and fried food.
Patients Concern
Disease/Condition Glossary
Nausea/Vomiting: Nausea is an uneasy feeling in the stomach that may come and go in waves in which a person feels a strong urge to vomit. It happens before vomiting. Vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. Usually, your child can face nausea and vomiting as the unpleasant effects of cancer therapy after chemotherapy. It is essential to control vomiting and nausea in cancer patients for performing everyday activities of the day. If not controlled, it can lead to mental changes, loss of appetite, malnutrition, and dehydration. CLEBOPRIDE is used in the treatment of moderately emetogenic cancer chemotherapy in children.
