Clindamycin+clotrimazole
About Clindamycin+clotrimazole
Clotrimazole+clindamycin is used to treat vaginal infections caused by bacteria (bacterial vaginosis), yeast infection (candidiasis) and parasitic infections (trichomoniasis). Bacterial vaginosis is caused by the change in the normal balance of vaginal bacteria. Vaginal yeast infection or Candidiasis is the infection of the vagina and tissues at the opening of the vagina (vulva).
Clotrimazole+clindamycin comprises Clindamycin and Clotrimazole. Clindamycin works by inhibiting bacterial protein synthesis, which is required for bacterial survival. Clotrimazole kills fungi by causing holes in their cell membranes, allowing their contents to leak.
Common side effects of Clotrimazole+clindamycin include a burning sensation, irritation and itching. These side effects may not occur in every patient using this medication and may vary from patient to patient. If the side effects persist or worsen, please seek medical advice.
Inform your doctor if you are allergic to Clotrimazole+clindamycin or any of its components. Let your doctor know if you have any liver, kidney, and gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), allergic conditions, diabetes and immune system problems (HIV/AIDS). Pregnant and breastfeeding women should consult a doctor before using Clotrimazole+clindamycin.
Uses of Clindamycin+clotrimazole
• Treatment of Vaginal Infections: Clotrimazole+clindamycin is widely used to alleviate symptoms of fungal infections and bacterial infections, particularly those caused by Candida species.
• Relief from Itching and Irritation: Clotrimazole+clindamycin help soothe discomfort, including itching, burning, and irritation associated with vaginal infections.
• Restoring Vaginal Flora: Clotrimazole+clindamycin aid in rebalancing the natural bacteria and fungi in the vaginal area, minimizing the likelihood of recurrent infections.
Medicinal Benefits
- Clotrimazole+clindamycin is used to treat vaginal infections like bacterial vaginosis (BV), candidiasis, and trichomoniasis.
- It comprises two medicines: 'Clindamycin' (antibiotic) and 'Clotrimazole' (antifungal).
- It shows a bacteriostatic effect, which stops bacterial reproduction.
- Clotrimazole is an imidazole antifungal medication that stops the growth of fungi by causing damage and leakage to the fungal cell membrane.
- Clotrimazole+clindamycin treats vaginal infections caused by bacteria, yeast and parasites, preventing white discharge, itchiness and inflammation in the genitourinary area.
Directions for Use
- Clotrimazole+clindamycin is for vaginal use only.
- It is usually applied once daily at bedtime or as prescribed by your doctor.
- Check the label for directions before using this medication.
- Take the medicine and place it on the applicator. Lie relaxed on your back. Gently insert the applicator tip into the vagina and push the plunger to release the medicine into the vagina.
- If you are inserting without an applicator, place Clotrimazole+clindamycin on your clean finger and gently insert it into the vagina.
- After use, remove the applicator and wash it thoroughly with warm, soapy water.
Storage
Side Effects of Clindamycin+clotrimazole
- Burning sensation
- Irritation
- Itching
Drug Warnings
- Please inform your doctor if you use any prescription, non-prescription medicines, including vitamins and herbal supplements, before using Clotrimazole+clindamycin.
- Do not use Clotrimazole+clindamycin if you are allergic to Clotrimazole+clindamycin or any of its components.
- Let your doctor know if you have any liver, kidney and gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), allergic conditions (asthma, hay fever, eczema), diabetes and immune system problems (HIV-AIDS).
- It is advised to use Clotrimazole+clindamycin under your doctor's supervision if you use other azole antifungal medicines.
- Clotrimazole and mineral oil additive in Clotrimazole+clindamycin may weaken the rubber product's activity (such as latex condoms, diaphragms, cervical caps).
Drug Interactions
Drug-Drug Interaction: Clotrimazole+clindamycin may interact with anaesthetic agents/skeletal muscle relaxants (atracurium, cisatracurium, doxacurium, mivacurium, pancuronium, pipecuronium, rapacuronium, rocuronium, vecuronium, succinylcholine, tubocurarine, and metocurine) and respiratory drugs (budesonide, formoterol).
Drug-Food Interaction: No interaction found/established.
Drug-Disease Interaction: Before using Clotrimazole+clindamycin, let your doctor know if have any liver, kidney, and gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), allergic conditions (asthma, hay fever, eczema), diabetes, and immune system problems (HIV-AIDS).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
safe if prescribedNo interaction found/established.
Pregnancy
consult your doctorThere are limited studies on how Clotrimazole+clindamycin affects the unborn baby during pregnancy. It is advised to use Clotrimazole+clindamycin after consulting your doctor.
Breast Feeding
safe if prescribedThere is limited data on how Clotrimazole+clindamycin affects breastfeeding infants. However, systemic absorption of Clotrimazole+clindamycin is negligible after topical and vaginal administration. Consult your doctor for further advice.
Driving
safe if prescribedNo interaction found/established.
Liver
consult your doctorLet your doctor know if you have any history of liver diseases before using Clotrimazole+clindamycin.
Kidney
consult your doctorLet your doctor know if you have any history of kidney diseases before using Clotrimazole+clindamycin.
Children
unsafeClotrimazole+clindamycin is not recommended for children below 12 years of age. Do not give this medicine to your child without medical advice.
Habit Forming
Diet & Lifestyle Advise
- Avoid frequent douching to maintain the natural moisture in the vagina.
- Use mild soap while taking baths and prefer warm baths.
- Avoid harsh products on your skin.
- Manage stress, eat healthily, drink plenty of water, exercise regularly and get plenty of sleep.
- Avoid or limit alcohol and caffeine intake.
- Wear under cotton underwear and pantyhose with a cotton crotch, which helps to prevent vaginal inflammation and irritation.
Special Advise
Ask your partner to use condoms during sexual intercourse, which will help to prevent the further spread of sexually transmitted infections like gonorrhoea if exists presently.
Proper hygiene and regular cleaning/washing of the genitourinary area with anti-infective wash is advisable.
Patients Concern
Disease/Condition Glossary
Vaginal infection: It is also referred to as ‘Vaginitis’, which can cause infection or inflammation of the vagina or external part of the vagina, known as the vulva. Vaginal infections are generally caused due to bacteria, yeast and parasites. White thick heavy discharge, foul odour, and intense itchiness around the genitourinary area are the main characteristics of vaginal infections.
Vaginal bacterial infection: It causes a greyish-white or yellow discharge with a fish-like odour that can be observed after sexual intercourse.
Vaginal yeast infection: It usually produces intense itching with sometimes white, viscous discharge.
Vaginal Trichomoniasis: It is a parasitic infection that produces intense vaginal itching with a foul odour. Vaginal discharge colour is usually greenish-yellow.
FAQs
Clotrimazole+clindamycin is used to treat vaginal infections caused by bacteria (bacterial vaginosis), yeast (candidiasis) and parasite (trichomoniasis).
Clotrimazole+clindamycin is used to treat vaginal infections, such as bacterial vaginosis (BV), candidiasis and trichomoniasis. It consists of Clindamycin (antibiotic) and Clotrimazole (antifungal). Clindamycin is an antibiotic that works by inhibiting bacterial protein synthesis, thereby blocking bacterial growth. Clotrimazole is an antifungal medication that stops fungal growth by damaging and leaking the fungal cell membrane.
Clotrimazole+clindamycin should be used with proper caution and doctor consultation if you have any liver, kidney and gastrointestinal diseases (diarrhoea and colitis, an inflammation of the colon), allergic conditions (asthma, hay fever, eczema), diabetes and immune system problems (HIV-AIDS).
Do not stop using Clotrimazole+clindamycin even if you feel better until the doctor's advised course is finished. Your symptoms may improve before the infection is completely cured.
Bacterial infections, yeast infections, parasitic infections, vaginal atrophy after menopause and irritants like body wash/soap/perfumes/vaginal contraceptives devices are some of the common causes of vaginal infections.
Your doctor might ask you a few questions about your sexual health, like your history of past vaginal infections or if you have had any sexually transmitted infections (STIs) like gonorrhoea. Besides this, your doctor might also perform a pelvic exam by collectinga vaginal discharge sample.
No, you should not use Clotrimazole+clindamycin for any white discharge without consulting a healthcare professional. While this medication is effective for treating certain vaginal infections, such as bacterial vaginosis and yeast infections, it's important to have a proper diagnosis to ensure you're using the right treatment.
Engaging in sexual activity or using vaginal products during treatment can potentially reduce the concentration of the medication in the vagina, potentially affecting its ability to treat the infection. It's important to follow this doctor's advice closely to ensure the medication's effectiveness.
If you don't experience improvement after using Clotrimazole+clindamycin, it's important to consult with your healthcare professional.
Storage: Keep Clotrimazole+clindamycin in a cool, dry place away from sunlight and heat. Do not store it in the fridge or freezer. Keep it out of reach of children. Disposal: Do not flush Clotrimazole+clindamycin down the toilet. Follow the instructions on the packaging or ask your pharmacist for guidance on safe disposal.
Clotrimazole+clindamycin comprises two medicines: Clindamycin (antibiotic) and Clotrimazole (antifungal).
Common side effects of Clotrimazole+clindamycin include a burning sensation, irritation and itching. These side effects may not occur in every patient using this medication and may differ individually. If the side effects persist or worsen, please seek medical advice.
Clotrimazole+clindamycin is not recommended for children below 12 years of age. Do not give this medicine to your child without medical advice.
There are limited studies on how Clotrimazole+clindamycin affects the unborn baby during pregnancy. It is advised to use Clotrimazole+clindamycin after consulting your doctor.
