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Chloramphenicol+hydrocortisone

About Chloramphenicol+hydrocortisone

Chloramphenicol+hydrocortisone is used to treat bacterial infections and eye inflammation. Bacterial eye infection occurs when harmful bacteria enter any part of the eyeball or surrounding tissues, including the cornea (front surface of the eye) and the lining of the outer eye and inner eyelids (conjunctiva). The common symptoms of eye infections are red eyes, pain, discharge, watery eyes, dry eyes, light Sensitivity, swollen eyes, itching, and blurred vision.

Chloramphenicol+hydrocortisone is a combination of two antibiotics: Hydrocortisone and Chloramphenicol. Hydrocortisone is a steroid medication that works by calming the body's immune response, thereby decreasing itching, pain, and swelling (inflammation) in the eye. Chloramphenicol is bacteriostatic, which prevents bacteria's growth by inhibiting the production of essential proteins necessary for bacteria to grow, multiply, and increase in numbers. Together, as a combined product, Chloramphenicol+hydrocortisone prevents the spread of eye infections caused by a wide range of gram-negative bacteria that cause eye infections.

Use Chloramphenicol+hydrocortisone as prescribed by your doctor. Chloramphenicol+hydrocortisone is only for use in the eyes. Do not swallow or inject Chloramphenicol+hydrocortisone. You are advised to use Chloramphenicol+hydrocortisone for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience redness, itching, irritation, burning/stinging sensations in the eyes, blurred vision, Sensitivity to light, eyelid swelling, itching, or crusting. Most of these side effects of Chloramphenicol+hydrocortisone do not require medical attention and typically resolve on their own over time. However, if the side effects worsen or persist, please consult your doctor.

Please tell your doctor if you are allergic to Chloramphenicol+hydrocortisone or any other medicines. Chloramphenicol+hydrocortisone should be used with caution in children. You are advised to consult a doctor if you are pregnant or breastfeeding. You are recommended not to use contact lenses during Chloramphenicol+hydrocortisone as it may worsen the infection. If you get any new eye problem, an eye infection, or notice any allergic reactions such as itching or redness of the eye and a skin rash, please consult your doctor immediately. You are advised to maintain a 10-minute time gap between using Chloramphenicol+hydrocortisone and other eye drops. Please do not touch the container tip to your eye, eyelids, or surrounding areas, as this may contaminate the solution and cause eye infections.

Uses of Chloramphenicol+hydrocortisone

Chloramphenicol+hydrocortisone is used in the treatment of bacterial eye infections. Its specific uses include the following:
• Bacterial Conjunctivitis: Chloramphenicol+hydrocortisone is used to treat bacterial infection and inflammation of the conjunctiva. It helps reduce symptoms like eye redness, irritation, and discharge.
• Bacterial Keratitis: Chloramphenicol+hydrocortisone is used to treat infection and inflammation of the cornea. It helps relieve eye pain and prevent potential vision loss caused by corneal damage.
• Belpharitis: Chloramphenicol+hydrocortisone is used to reduce inflammation of the eyelids.
• Post-surgical Eye Inflammation: Chloramphenicol+hydrocortisone is used to prevent infections and reduce inflammation and swelling following eye surgeries.

Medicinal Benefits

Chloramphenicol+hydrocortisone is a combination medication used to treat bacterial eye infections. It contains Hydrocortisone and Chloramphenicol. Hydrocortisone is a steroid medication that works by calming the body's immune response, thereby decreasing itching, pain, and swelling (inflammation) in the eye. Chloramphenicol is bacteriostatic, which prevents bacteria's growth by inhibiting the production of essential proteins necessary for bacteria to grow, multiply, and increase in numbers. Together, Chloramphenicol+hydrocortisone prevents the spread of eye infections caused by a wide range of gram-negative bacteria causing eye infections.

Directions for Use

  • Chloramphenicol+hydrocortisone is for ophthalmic (for eye) use only.
  • Follow your doctor's instructions on the dosage and timing of this medication to ensure safe and effective use.
  • Wash your hands thoroughly before and after using this medicine. 
  • Lie down and tilt your head backwards. Gently pull your lower eyelid with your index finger to form a pocket. Place the prescribed amount of Chloramphenicol+hydrocortisone into the pocket. Close your eyes for 1-2 minutes. 
  • Replace the outer cap after use.
  • Avoid touching the container tip to your eye, eyelids, or surrounding areas to prevent contamination.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Chloramphenicol+hydrocortisone

  • Redness in eyes
  • Itching eyes
  • Irritation, burning, or stinging sensation in the eyes
  • Blurred vision
  • Increased sensitivity to light
  • Eyelid swelling

Drug Warnings

Chloramphenicol+hydrocortisone should not be used for an eye infection due to a virus, or another type of eye infection (e.g., tuberculosis, fungus),  without consulting with the doctor. After applying Chloramphenicol+hydrocortisone, your vision becomes blurred for some time, so you are advised not to drive or use any machine or activity that requires a clear vision. Long-term use of Chloramphenicol+hydrocortisone can enhance the risk of intraocular pressure (glaucoma), which can even damage the optic nerve and cause visual defects. Therefore, regular eye checkups are advised to monitor intraocular pressure. Chloramphenicol+hydrocortisone contains s benzalkonium chloride as an excipient that may discolour soft lenses, so try to avoid soft lenses for at least some time after using Chloramphenicol+hydrocortisone.

Drug Interactions

Drug-Drug Interactions: Chloramphenicol+hydrocortisone may interact with anticholinergic agents (atropine), HIV/AIDS drugs (ritonavir, cobicistat), antibiotics (erythromycin, amoxicillin, azlocillin, bacampicillin, ampicillin, tetracycline, and polymyxin B), an anti-epileptic drug (carbamazepine), and an anti-diabetic (chlorpropamide).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: Do not use Chloramphenicol+hydrocortisone if you have viral diseases of the cornea, eye infections caused by mycobacteria, or children under three years of age.

Drug-Drug Interactions Checker List:

  • ATROPINE
  • RITONAVIR
  • COBICISTAT
  • ERYTHROMYCIN
  • TETRACYCLINE
  • POLYMYXIN B
  • AMOXICILLIN
  • AMPICILLIN
  • AZLOCILLIN
  • CARBAMAZEPINE
  • CHLORPROPAMIDE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      The interaction of alcohol with Chloramphenicol+hydrocortisone is unknown. However, as a precautionary measure, limit or avoid the consumption of alcohol.

    • Safety Warning

      Pregnancy

      caution

      The safety of Chloramphenicol+hydrocortisone in pregnancy is unknown, so it is advised that you should consult with a doctor, as Chloramphenicol+hydrocortisone can only be given after careful consideration of the benefit/risk ratio.

    • Safety Warning

      Breast Feeding

      caution

      Chloramphenicol+hydrocortisone should not be used in nursing mothers unless clearly necessary. So, inform your doctor if you are a nursing mother. Your doctor will weigh the benefits and potential risks before prescribing Chloramphenicol+hydrocortisone.

    • Safety Warning

      Driving

      unsafe

      Chloramphenicol+hydrocortisone may cause blurred vision and reduced visual acuity immediately after use, so it is advisable to avoid driving and using machines.

    • Safety Warning

      Liver

      caution

      If you have liver problems, consult your doctor before using Chloramphenicol+hydrocortisone.

    • Safety Warning

      Kidney

      caution

      If you have kidney problems, consult your doctor before using Chloramphenicol+hydrocortisone.

    • Safety Warning

      Children

      unsafe

      Chloramphenicol+hydrocortisone should not be used in children below three years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Wash your hands with soap and water frequently.
    • Keep your clothes, towels, and bedsheets separate from others.
    • Maintain good hygiene of contact lenses. Wash your hands thoroughly before putting in and after taking out contact lenses.
    • Avoid wearing contact lenses while swimming. If you use them incorrectly, get a new pair.
    • Wear protective eyegear if you are cycling or trekking through the forest.
    • If you experience eye irritation, avoid rubbing your eyes.

    Special Advise

    • Please consult an eye specialist if your eye infection persists or worsens after using Chloramphenicol+hydrocortisone for a week.

    Patients Concern

    Disease/Condition Glossary

    Bacterial eye infections: Bacterial eye infections occur when harmful bacteria enter any part of the eyeball or surrounding tissues, including the cornea ( front surface of the eye) and lining of the outer eye and inner eyelids (conjunctiva). The common symptoms of eye infections are red eyes, pain, discharge, watery eyes, dry eyes, light sensitivity, swollen eyes, itching, and blurred vision. Whenever anyone faces an eye infection, it is advisable to visit an eye doctor for an eye exam to identify the condition. Self-diagnosis can delay effective treatment and even cause permanent vision loss. Conjunctivitis, or pink eye, is a common, highly contagious bacterial eye infection that generally spreads in children in classrooms and similar environments. The transparent layer's inflammation (conjunctiva) lines the eyelid and covers the white part of the eyeball. It causes a bacterial infection, resulting in an inflamed conjunctiva, which makes the white part of the eyeball appear pink.

    FAQs

    Chloramphenicol+hydrocortisone is used to treat bacterial eye infections. It is used for treating infectious diseases of the eyelids, the cornea (the transparent part that covers the front part of the eye), conjunctiva (which lines the inner surfaces of the eyelids), and anterior ocular segment (front of the eye).

    Chloramphenicol+hydrocortisone is a combination of two antibiotics, namely Hydrocortisone and Chloramphenicol. Hydrocortisone is a steroid medication that works by calming the body's immune response, thereby decreasing itching, pain, and swelling (inflammation) in the eye. Chloramphenicol is bacteriostatic, which prevents bacteria's growth by inhibiting the production of essential proteins necessary for bacteria to grow, multiply, and increase in numbers. Together as a combined product, Chloramphenicol+hydrocortisone prevents the spread of eye infections caused by a wide range of gram-negative bacteria.

    Chloramphenicol+hydrocortisone should not be used by individuals who are allergic to any of its ingredients, or those with certain types of eye infections, such as viral or fungal infections, where this medication would not be effective. It should also be avoided in people with a history of serious blood disorders or those who have experienced problems with bone marrow function. Use during pregnancy or breastfeeding should only be under medical advice. In general, it is important to use this medication only when prescribed by a doctor, who will consider your overall health, medical history, and the nature of the eye condition.

    Regular eye check-ups are essential for protecting your vision and overall health. They help detect eye diseases like glaucoma and macular degeneration early, often before symptoms appear, allowing timely treatment to prevent permanent vision loss. Eye exams can also detect signs of other health issues, such as diabetes, high blood pressure, and certain types of cancer. Regular check-ups ensure early detection, help prevent vision loss, and support overall health.

    Usually, Chloramphenicol+hydrocortisone starts showing its effects just after using it. However, it will take some days to completely improve the eye condition.

    You are not recommended to wear contact lenses during the entire course of Chloramphenicol+hydrocortisone as it may worsen the infection. Therefore, you are advised to remove contact lenses before using Chloramphenicol+hydrocortisone and reinsert them after 24 hours of finishing the course of Chloramphenicol+hydrocortisone.

    You are recommended to maintain a minimum of 10 minutes time gap between using Chloramphenicol+hydrocortisone and other eye drops, and administer eye ointments last.

    You are not recommended to stop using Chloramphenicol+hydrocortisone without consulting your doctor, as it may increase eye pressure and lead to loss of vision. Therefore, use Chloramphenicol+hydrocortisone for as long as your doctor has prescribed it. If you experience any difficulty while using Chloramphenicol+hydrocortisone, please consult your doctor.

    Chloramphenicol+hydrocortisone starts to work as soon as you apply it. However, it will take some days to fully improve the eye condition. Therefore, continue using Chloramphenicol+hydrocortisone for the prescribed duration for the full benefits.

    Do not stop using Chloramphenicol+hydrocortisone if you feel better. Stopping Chloramphenicol+hydrocortisone before the prescribed duration may cause the infection to recur. Therefore, use Chloramphenicol+hydrocortisone for as long as the doctor has prescribed it.

    The side effects of Chloramphenicol+hydrocortisone include itching, redness, irritation, blurred vision, burning or stinging sensations in the eyes, sensitivity to light, and eyelid swelling. Consult the doctor if any of these side effects persist or worsen.

    Available Medicines for

    Chloramphenicol+hydrocortisone

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