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Clomiphene Citrate+n Acetylcysteine

About Clomiphene Citrate+n Acetylcysteine

Clomiphene Citrate+n Acetylcysteine is used to treat female infertility caused by ovulatory disorders. It helps in maintaining the hormonal balance in the body and improving pregnancy rates. Female infertility is a condition in which a woman is unable to conceive despite frequent unprotected sex for at least a year.

Clomiphene Citrate+n Acetylcysteine is a combination medication. It contains clomiphene citrate and N-acetylcysteine. Clomiphene Citrate+n Acetylcysteine treats infertility by enhancing the success rate of pregnancy and conception through the mechanism of follicle stimulation. Clomiphene Citrate+n Acetylcysteine stimulates the brain to release a surge of reproductive hormones, which in turn act on ovarian follicles and promote ovulation (the release of egg cells from the ovary). Clomiphene Citrate+n Acetylcysteine is also a potent antioxidant and is useful in promoting overall health, nutrition, and well-being.

Clomiphene Citrate+n Acetylcysteine is available only with a prescription. Take Clomiphene Citrate+n Acetylcysteine as prescribed by a doctor. Clomiphene Citrate+n Acetylcysteine may be taken with or without food. In some cases, Clomiphene Citrate+n Acetylcysteine may cause certain common side effects such as mood swings, headache, dizziness, flushing (sudden reddening) of the skin, cloudy lenses in the eye (cataracts), nausea, vomiting, or diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

Inform your doctor in case of any history of menstrual problems, ovarian cysts, polycystic ovary syndrome (PCOS), stomach ulcers, liver disease, kidney disease, or cardiac disorders. Keep your doctor informed of your entire medical history, including any history of hormone-dependent cancers, asthma, high blood cholesterol, anorexia, or fits/epilepsy. Consult your doctor if you are planning to get pregnant before taking Clomiphene Citrate+n Acetylcysteine during pregnancy or if you are breastfeeding.

Uses of Clomiphene Citrate+n Acetylcysteine

Clomiphene Citrate+n Acetylcysteine is used to treat female infertility. The detailed uses of Clomiphene Citrate+n Acetylcysteine are as follows: • Treats ovulatory disorders: Clomiphene Citrate+n Acetylcysteine helps stimulate ovulation in women who have difficulty releasing eggs regularly. • Treats hormonal imbalances: Clomiphene Citrate+n Acetylcysteine supports the correction of irregular menstrual cycles linked to infertility. • Treats polycystic ovarian syndrome (PCOS)-related infertility: Clomiphene Citrate+n Acetylcysteine improves ovulation and increases the chances of conception in women with PCOS. • Treats oxidative stress in reproductive health: Clomiphene Citrate+n Acetylcysteine contains N-acetylcysteine, which acts as an antioxidant to support healthy ovarian function.

Medicinal Benefits

Clomiphene Citrate+n Acetylcysteine is an ovarian stimulant. It contains clomiphene citrate and N-acetylcysteine. It is used primarily to improve female fertility in those suffering from problems related to the proper release of the egg cells (ovulation). Clomiphene citrate is an ovarian stimulant and selective estrogen receptor modulator (SERM). It regulates the levels of estrogen in the body and increases the release of gonadotropic hormones FSH and LH, which in turn, act on the ovaries and follicles to augment the liberation of eggs from inside the follicles, thereby making the egg cells available and approachable for fertilization by male sperm. N-acetylcysteine is a powerful antioxidant and is useful in enhancing spontaneous ovulation and pregnancy rates while also regulating menstruation, periods, and overall reproductive health. Together, Clomiphene Citrate+n Acetylcysteine helps treat infertility and supports hormonal balance and gynecological health.

Directions for Use

  • Clomiphene Citrate+n Acetylcysteine can be taken with or without food.
  • Follow your doctor’s instructions on the dosage and timing of this medication.
  • Swallow Clomiphene Citrate+n Acetylcysteine as a whole with a glass of water.
  • Do not crush, break, or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Clomiphene Citrate+n Acetylcysteine

  • Mood swings
  • Headache
  • Dizziness
  • Flushing (sudden reddening) of the skin
  • Cloudy lenses in the eye (cataracts)
  • Nausea
  • Vomiting
  • Diarrhoea

Drug Warnings

Clomiphene Citrate+n Acetylcysteine should not be used in case of any known allergy to either of the components. Clomiphene Citrate+n Acetylcysteine should be used with caution in case of high risk or previous history of any cardiovascular health disorders or endocrinological issues such as diabetes, hypothyroidism, or any hormonal disturbances. Clomiphene Citrate+n Acetylcysteine is not recommended for use in children, men, adolescents or post-menopausal women. Clomiphene Citrate+n Acetylcysteine may increase the risk of breast or any hormone-dependent cancer. Clomiphene Citrate+n Acetylcysteine should be used with caution in those with heart problems, established infertility, peptic ulcer disease, liver diseases, blood clotting problems, kidney disease, and/or polycystic ovarian syndrome. Keep your doctor informed of your entire medical history, including any history of hormone-dependent cancers, asthma, high blood cholesterol, lactose intolerance, anorexia, or fits/epilepsy. Inform your doctor before using Clomiphene Citrate+n Acetylcysteine if you are pregnant or breastfeeding. Let your doctor know if you are already on any hormonal therapy or on treatment with antitussives (cough medicines), antibiotics, activated charcoal, and heart medicines for angina.

Drug Interactions

Drug-Drug Interactions: Clomiphene Citrate+n Acetylcysteine may interact with Janus Kinase (JAK) Inhibitors (abrocitinib, baricitinib), retinoids (bexarotene), and chemotherapy drugs (ifosfamide).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Clomiphene Citrate+n Acetylcysteine should be used with caution in patients with a known hypersensitivity disorder, abnormal uterine bleeding, breast, asthma, Addison’s disease, hepatic dysfunction, hepatic encephalopathy, pituitary inactivity, and high blood cholesterol.

Drug-Drug Interactions Checker List:

  • ABROCITINIB
  • BARICITINIB
  • BEXAROTENE
  • IFOSFAMIDE
  • Safety Advice

    • Safety Warning

      Alcohol

      consult your doctor

      There is limited information on the effects of alcohol when taken with Clomiphene Citrate+n Acetylcysteine. Please discuss with your doctor if you have any concerns.

    • Safety Warning

      Pregnancy

      unsafe

      Clomiphene Citrate+n Acetylcysteine is not recommended for use during pregnancy as it may cause birth defects or miscarriage. Please consult your doctor if you have any concerns.

    • Safety Warning

      Breast Feeding

      consult your doctor

      Clomiphene Citrate+n Acetylcysteine may decrease the amount of milk produced. Therefore, take your doctor's advice before taking Clomiphene Citrate+n Acetylcysteine if you a breastfeeding mother.

    • Safety Warning

      Driving

      caution

      You may experience vision problems, such as blurred vision, while taking Clomiphene Citrate+n Acetylcysteine. If this occurs, avoid driving or using any tools or machines.

    • Safety Warning

      Liver

      unsafe

      Clomiphene Citrate+n Acetylcysteine may worsen pre-existing liver disease. Please consult your doctor if you have any concerns.

    • Safety Warning

      Kidney

      caution

      Clomiphene Citrate+n Acetylcysteine should be used with caution in those with pre-existing kidney disease. Please consult your doctor in case of any concerns.

    • Safety Warning

      Children

      unsafe

      Clomiphene Citrate+n Acetylcysteine is not recommended for children under 12 years of age.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Reducing weight and having a healthy BMI is very important to improve fertility.
    • Avoid smoking to improve fertility.
    • Avoid caffeine and caffeinated drinks. Eat foods rich in antioxidants like zinc and folate and cut down on carbs. Increase your fibre intake.
    • Incorporate foods rich in omega 3 fatty acids in your diet such as flax seeds, chia seeds and walnuts which help regulate hormones and improve infertility.
    • Manage stress by practicing stress relaxation techniques like yoga, meditation or deep breathing exercises.
    • Your doctor may ask you to record your daily temperature every morning and make a chart of your body temperature to help determine when ovulation will occur (as body temperature tends to be slightly higher around then). The timing of sex and ovulation is important for Clomiphene Citrate+n Acetylcysteine to show its benefits. Your doctor will advise you on the same.

    Special Advise

    • Do not discontinue taking Clomiphene Citrate+n Acetylcysteine abruptly or without the advice of the physician.
    • Please know that your doctor may order blood tests to check your hormone levels while you are on Clomiphene Citrate+n Acetylcysteine.
    • Your doctor will also recommend frequent pelvic examinations while you are on treatment with Clomiphene Citrate+n Acetylcysteine.
    • Clomiphene Citrate+n Acetylcysteine is not usually given for more than 5 days in one course.
    • Bring any mood swings or mood changes to your doctor’s attention. Please see a mental health care professional if needed.
    • Before starting Clomiphene Citrate+n Acetylcysteine, speak to your doctor about the risk of multiple pregnancies (twins or triplets) and ectopic pregnancy (where the baby grows outside the uterus).

    Patients Concern

    Disease/Condition Glossary

    Female Infertility: Female infertility is defined as the inability to get pregnant despite frequent unprotected sex for at least one year (or 6 months, if 35 years of age). Age, weight, hormones, and other organic causes are usually responsible for infertility. However, in most cases, it is a treatable condition.

    FAQs

    Clomiphene Citrate+n Acetylcysteine is used for treating female infertility caused by ovulatory disorders. It helps in maintaining the hormonal balance in the body and improving pregnancy rates by inducing the release of egg cells in a process called ovulation.

    Clomiphene Citrate+n Acetylcysteine works through ovarian stimulation and the release of healthy egg cells. Clomiphene Citrate+n Acetylcysteine also works as an antioxidant and helps build reproductive health.

    While Clomiphene Citrate+n Acetylcysteine does regulate your menstrual cycles, it is not routinely indicated in the treatment of heavy periods (menorrhagia). Talk to your doctor if you have any concerns.

    Clomiphene Citrate+n Acetylcysteine is not recommended for those suffering from liver disease. Keep your doctor informed in case of a history of liver disease.

    Infertility can be due to various root causes. While Clomiphene Citrate+n Acetylcysteine definitely helps improve pregnancy rates by stimulating ovulation, it is best to consult your gynecologist for concerns related to fertility and conception.

    Individuals with a history of cancer, particularly hormone-related or breast cancer, should use Clomiphene Citrate+n Acetylcysteine with caution. Please consult your doctor for advice and disclose your complete medical history before use.

    Clomiphene Citrate+n Acetylcysteine is effective if used as per the dose and duration prescribed by your doctor. Do not stop taking Clomiphene Citrate+n Acetylcysteine early, even if you notice improvement, as it may increase recurring failure of treatment.

    Yes, Clomiphene Citrate+n Acetylcysteine can cause dizziness as a side effect in some people. However, if you feel dizzy, you are recommended to avoid driving or performing any activity.

    Yes, Clomiphene Citrate+n Acetylcysteine increases the chances of pregnancy by inducing ovulation. It promotes the release of eggs from the ovary. Thus, it enhances the probability of becoming pregnant while taking Clomiphene Citrate+n Acetylcysteine.

    Ideally, you should have sex after 5 to 10 days of taking Clomiphene Citrate+n Acetylcysteine. However, your doctor may regularly examine you during the treatment and recommend you the best possible days. If you have any concerns, please discuss them with your doctor.

    The common side effects associated with Clomiphene Citrate+n Acetylcysteine include mood swings, headache, dizziness, flushing (sudden reddening) of the skin, cloudy lenses in the eye (cataracts), nausea, vomiting, or diarrhoea. If these side effects persist or worsen, please consult your doctor.

    Available Medicines for

    Clomiphene Citrate+n Acetylcysteine

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