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About DALBAVANCIN

DALBAVANCIN is an antibiotic used to treat skin and skin structure infections. A bacterial infection occurs when harmful bacteria enter the body, multiply and cause infection. 

DALBAVANCIN contains Dalbavancin, which belongs to the cyclic lipoglycopeptide class of antibiotics. It works by inhibiting the process of bacterial cell wall synthesis that is required for its survival. 

DALBAVANCIN may cause certain common side effects such as injection site reactions, rash, vomiting, allergic reaction, dizziness, headache, flushing, nausea, and diarrhoea. If these side effects persist, contact your doctor immediately. A qualified healthcare doctor will administer the medicine to you. Hence, do not self-administer.

DALBAVANCIN should be avoided if you are allergic to it or other antibiotics. Caution should be exercised, and inform your doctor if you have any history of liver/kidney disease, heart problems, or any other medical conditions. Inform your doctor if you have/had diarrhoea for more than four days. Pregnant or breastfeeding mothers should receive DALBAVANCIN only if prescribed by the doctor.

Uses of DALBAVANCIN

Skin and skin structure infections

Medicinal Benefits

DALBAVANCIN is a broad-spectrum antibiotic that is effective against gram-positive bacterial infections. Infectious or harmful bacteria can make you sick and reproduce quickly in your body. DALBAVANCIN contains Dalbavancin, which belongs to the cyclic lipoglycopeptide class of antibiotics. It works against various types of bacteria by inhibiting the bacterial cell wall synthesis that is required for its survival. Thus, DALBAVANCIN kills bacteria and prevents the growth of bacterial infection. DALBAVANCIN is only effective in treating infections caused by bacteria and is not effective for viral infections like the flu or a common cold.

Directions for Use

A qualified healthcare professional will administer a dose of DALBAVANCIN. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DALBAVANCIN

  • Nausea

  • Vomiting

  • Stomach pain

  • Diarrhoea

  • Dizziness

  • Flushing

  • Chest pain

  • Injection site reactions

  • Headache

In-Depth Precautions and Warning

Drug Warnings

Discontinue and inform your doctor if you observe any allergic reactions or if you are known allergic to it or other antibiotics. DALBAVANCIN should be used with caution if you have liver problems, kidney disease, heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level). If you are pregnant or breastfeeding, inform your doctor before receiving DALBAVANCIN. This medicine is not recommended for use in children below 12 years of age as the safety and efficacy is not established. DALBAVANCIN may cause diarrhoea as a side effect. Inform your doctor if it persists for more than four days. However, do not take any anti-diarrheal medicine until your doctor tells you. DALBAVANCIN may cause hypersensitivity reactions and infusion-related reactions. Hence, the patient should be observed for any changes during the treatment.

Drug Interactions

Drug-Drug Interactions: DALBAVANCIN may interact with CYP450 substrates (amlodipine, alprazolam, clopidogrel, warfarin), CYP450 inhibitors (amitriptyline, haloperidol, clarithromycin, ketoconazole).

Drug-Food Interactions: Avoid consumption of alcohol while receiving DALBAVANCIN as it can cause serious side effects. 

Drug-Disease Interactions: Caution should be exercised in patients with renal dysfunction, liver disease, and cardiac problems before receiving DALBAVANCIN. 

Drug-Drug Interactions Checker List:

  • AMLODIPINE
  • ALPRAZOLAM
  • CLOPIDOGREL
  • WARFARIN
  • CLARITHROMYCIN
  • AMITRIPTYLINE
  • KETOCONAZOLE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consuming alcohol while on treatment with DALBAVANCIN as it may worsen your condition.

    • Safety Warning

      Pregnancy

      caution

      Limited data is available on the use of DALBAVANCIN in pregnancy. So, inform your doctor if you are pregnant or planning a pregnancy before receiving DALBAVANCIN.

    • Safety Warning

      Breast Feeding

      caution

      Limited data is available on the use of DALBAVANCIN in breastfeeding. It should not be used unless clearly necessary. So, inform your doctor if you are breastfeeding your child before receiving DALBAVANCIN.

    • Safety Warning

      Driving

      unsafe

      Avoid driving vehicles or operating machines after taking this medicine, as DALBAVANCIN causes dizziness and makes you feel sleepy or dizzy.

    • Safety Warning

      Liver

      caution

      If you have a pre-existing or a history of liver disease, inform your doctor before receiving DALBAVANCIN. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

    • Safety Warning

      Kidney

      caution

      DALBAVANCIN should be used with caution in patients with kidney disease. Inform your doctor if you have kidney problems. Your doctor will prescribe only if the benefits outweigh the risks. Your doctor may adjust the dose based on your health condition if prescribed.

    • Safety Warning

      Children

      unsafe

      DALBAVANCIN is not recommended for use in children below 12 years of age as the safety and efficacy are not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Diarrhea may happen as a side effect. Taking probiotics after receiving DALBAVANCIN may help. Talk to your doctor if you notice blood stools or develop stomach cramps.

    • Drink plenty of fluids to avoid an upset stomach and hydrate your body.

    • Avoid intake of alcoholic beverages with DALBAVANCIN as it can make you dehydrated and may affect your sleep. This can make it harder for your body to aid the DALBAVANCIN in fighting off infections.

    • Maintain good hygiene and avoid contaminated or processed food.

    • Include more fibre-enriched food like whole-grain bread and brown rice in your diet, as it can be easily digested by your gut bacteria, which helps stimulate their growth. 

    • Avoid taking much calcium-enriched foods and drinks as it might affect the working of DALBAVANCIN.

    Special Advise

    • Even if you feel better after receiving DALBAVANCIN, do not stop the administration of it. This might cause the symptoms to reappear and will make the infection difficult to treat due to antibiotic resistance.

    • Stop receiving DALBAVANCIN and consult your doctor immediately if you develop any allergic reactions such as itching, skin rash, swelling of the face, throat, tongue, and breathing difficulties.

    • Your doctor may suggest a blood test to check your liver and kidney functioning.

    Patients Concern

    Disease/Condition Glossary

    Bacterial skin and skin structure infections: Bacterial skin and skin structure infections, also known as skin and soft tissue infections, are infections associated with skin and soft tissues (mucous membrane and loose connective tissue). It can be complicated and uncomplicated skin and skin structure infections. Symptoms include swelling, rashes, itching, pus, pain, and redness.

    FAQs

    How does DALBAVANCIN work?

    DALBAVANCIN contains Dalbavancin, an antibiotic that works by interfering with the formation of the bacterial cell wall.

    How can I manage diarrhoea as a side effect of DALBAVANCIN?

    Do not use anti-diarrhoeal medication until the doctor has prescribed you. You can drink plenty of fluids (electrolytes) to avoid dehydration. Besides this, you can also take prebiotics or probiotics to manage diarrhoea, as they may help increase the number of good bacteria in the intestine, aiding digestion.

    How long does DALBAVANCIN take to work?

    As DALBAVANCIN is injectable, it can start working soon after administration. However, DALBAVANCIN may take a few days to kill the bacteria and prevent further spread of infection.

    Available Medicines for

    DALBAVANCIN