Dexlansoprazole+domperidone
About Dexlansoprazole+domperidone
Dexlansoprazole+domperidone is used to treat gastroesophageal reflux disease (GERD), heartburn, indigestion, peptic ulcer and stomach discomfort. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.
Dexlansoprazole+domperidone is a combination of two drugs, namely, Dexlansoprazole and Domperidone. It reduces the amount of acid produced by the stomach while preventing excess acid from flowing back into the food pipe. As a result, food moves more rapidly through the stomach and into the intestine.
Take Dexlansoprazole+domperidone as prescribed by your doctor. Dexlansoprazole+domperidone may cause common side effects such as diarrhoea, nausea, vomiting, dry mouth, stomach pain, or gas. However, if the side effects persist or worsen, please consult your doctor.
Please tell your doctor if you are allergic to Dexlansoprazole+domperidone or any other ingredients in Dexlansoprazole+domperidone. If you are pregnant or breastfeeding, please inform your doctor before taking Dexlansoprazole+domperidone.
Uses of Dexlansoprazole+domperidone
Medicinal Benefits
When taken as directed, Dexlansoprazole+domperidone may help offer the following benefits:
For GERD (acid reflux disease):
- Reduces excess stomach acid that causes chest burning and sour taste.
- Relieves discomfort such as chest pain, heaviness, and irritation.
- Supports healing of the food pipe lining and improves daily comfort.
For Acid Reflux and Heartburn:
- Reduces excess stomach acid and relieves a burning sensation.
- Helps prevent acid from flowing back into the food pipe.
For Peptic Ulcer Disease:
- Reduces excess stomach acid, helping ulcers heal properly
- Relieves stomach pain, burning, and irritation.
- Protects the stomach lining from further damage
Directions for Use
- Dexlansoprazole+domperidone can be taken before meals. Taking it after meals may delay its absorption.
- Follow your doctor’s instructions on the dosage and timing of this medication.
- Swallow Dexlansoprazole+domperidone as a whole with a glass of water.
- Do not break, crush, or chew it.
Storage
Side Effects of Dexlansoprazole+domperidone
- Diarrhoea
- Nausea
- Vomiting
- Dry mouth
- Headache
- Stomach pain
- Gas
Medicines Containing this Salt
View AllDrug Warnings
- If you are allergic to Dexlansoprazole+domperidone or any other ingredients in Dexlansoprazole+domperidone, please tell your doctor.
- If you are pregnant or breastfeeding, please inform your doctor before taking Dexlansoprazole+domperidone.
- If you have a prolactinoma (tumour of the pituitary gland), liver, or heart problems, inform your doctor before taking Dexlansoprazole+domperidone.
- Drive only if you are alert after taking Dexlansoprazole+domperidone.
- If you experience heart rhythm disorders like difficulty in breathing, loss of consciousness, or palpitations (strong or irregular heartbeat) while taking Dexlansoprazole+domperidone, contact your doctor immediately.
- Dexlansoprazole in Dexlansoprazole+domperidone may increase the risk of severe diarrhoea. Therefore, if you have stomach pain, watery stool, and fever that does not go away, contact your doctor right away.
Drug Interactions
Drug-Drug Interactions: Inform your doctor if you are taking any of these medicines, as there may be an interaction.
- Anticancer drugs (Pazopanib, Erlotinib)
• Potential effect: May interfere with absorption and reduce effectiveness. - Anti-HIV drugs (Nelfinavir, Atazanavir)
• Potential effect: May decrease absorption and blood levels, making it less effective. - Immunosuppressants (Tacrolimus)
• Potential effect: May increase blood levels and cause serious side effects. - Antimalarial drug (Halofantrine)
• Potential effect: May increase the risk of irregular heart rhythm.
Drug-Food Interaction: No interactions found.
Drug-Disease Interactions: Inform your doctor if you are suffering from any of these conditions.
- Low or high magnesium levels in the blood
- Prolactinoma (tumour of the pituitary gland)
- Blocked or perforated gut
- Stomach bleeding
- Kidney disease
- Liver disease
- Heart problems
Drug-Drug Interactions Checker List:
Safety Advice

Alcohol
consult your doctorThe interaction of Dexlansoprazole+domperidone with alcohol is unknown. If you have any concerns, discuss them with your doctor.

Pregnancy
consult your doctorIf you are pregnant or planning a pregnancy, please consult your doctor before taking Dexlansoprazole+domperidone.

Breast Feeding
consult your doctorIf you are a breastfeeding mother, please inform your doctor before taking Dexlansoprazole+domperidone.

Driving
consult your doctorIf you have any concerns about the effects of Dexlansoprazole+domperidone on driving, please discuss them with your doctor.

Liver
consult your doctorConsult your doctor before taking Dexlansoprazole+domperidone if you have any liver problems.

Kidney
consult your doctorConsult your doctor before taking Dexlansoprazole+domperidone if you have any kidney problems.

Children
consult your doctorIf you have any concerns regarding the use of Dexlansoprazole+domperidone for children, please consult a doctor.
Habit Forming
Diet & Lifestyle Advise
Eating Habits:
- Eat smaller meals more often to reduce stomach discomfort.
- Avoid lying down immediately after meals to prevent acid backflow.
Weight and Activity:
- Maintain a healthy weight with regular light exercise.
- Avoid sitting for long periods and take short walking or stretching breaks.
Clothing and Posture:
- Avoid tight-fitting clothes as they increase pressure on the stomach.
Food Choices:
- Avoid fatty, spicy foods, chocolate, citrus fruits, tomato, onion, garlic, tea, and soda.
Habits and Stress:
- Manage stress with yoga or meditation.
- Avoid smoking and alcohol, as they increase stomach acid and heartburn.
Patients Concern
Disease/Condition Glossary
Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets irritated or eroded, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid repeatedly flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, difficulty swallowing and a sour or bitter taste in the mouth.
FAQs
Dexlansoprazole+domperidone is used to treat gastroesophageal reflux disease (GERD) and relieve heartburn.
Dexlansoprazole+domperidone contains Dexlansoprazole and Domperidone. Dexlansoprazole reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, it provides relief from heartburn symptoms related to acid reflux. Domperidone increases stomach muscle contractions and motility. Also, it prevents reflux (the regurgitation of stomach contents back into the food pipe).
Dexlansoprazole+domperidone may cause dry mouth as a temporary side effect. It is not necessary for everyone taking Dexlansoprazole+domperidone to experience this side effect. To avoid such side effects, practice good oral hygiene, drink plenty of water, rinse your mouth regularly, and suck on sugar-free candy. However, please consult a doctor if the condition persists or worsens.
Dexlansoprazole+domperidone should be used with caution in patients suffering from kidney problems. Therefore, inform your doctor if you have any kidney problems before taking Dexlansoprazole+domperidone, so the dose can be adjusted appropriately.
Yes, Dexlansoprazole+domperidone can provide quick relief from GERD symptoms due to the combined action of its active ingredients. However, please consult a doctor before taking Dexlansoprazole+domperidone.
Dexlansoprazole+domperidone is generally well tolerated for long-term use, but regular doctor check-ups are recommended to monitor for potential adverse effects.
Dexlansoprazole+domperidone should not be taken by children, as its safety and effectiveness have not been established. If you have any concerns regarding this, please consult a doctor.
If you miss a dose of Dexlansoprazole+domperidone, take it as soon as you remember. If it is time for the next dose, skip the missed dose and continue taking the regular dose. Avoid taking a double dose to make up for a missed dose.
Dexlansoprazole+domperidone should be stored in a cool, dry place, away from sunlight. Keep it out of reach of children.

