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About DEXLANSOPRAZOLE+DOMPERIDONE

DEXLANSOPRAZOLE+DOMPERIDONE is used to treat gastroesophageal reflux disease (GERD) and relieve heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn.

DEXLANSOPRAZOLE+DOMPERIDONE is a combination of two drugs, namely, Dexlansoprazole and Domperidone. It works by inhibiting the action of proton pumps, which produce stomach acid. As a result, it reduces the amount of acid produced by the stomach while preventing excess acid from flowing back into the food pipe. It also inhibits dopamine receptors in the upper digestive tract. As a result, food moves more quickly through the stomach and into the intestine.

Take DEXLANSOPRAZOLE+DOMPERIDONE as prescribed by your doctor. You are advised to take DEXLANSOPRAZOLE+DOMPERIDONE for as long as your doctor has prescribed it for you based on your medical condition. DEXLANSOPRAZOLE+DOMPERIDONE may cause common side effects such as diarrhoea, nausea, vomiting, dry mouth, stomach pain, common cold or gas. Most of these side effects of DEXLANSOPRAZOLE+DOMPERIDONE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Please tell your doctor if you are allergic to Domperidone, Dexlansoprazole or any other ingredients in DEXLANSOPRAZOLE+DOMPERIDONE. If you are pregnant or breastfeeding, please inform your doctor before taking DEXLANSOPRAZOLE+DOMPERIDONE. If you have a prolactinoma (tumour of the pituitary gland), liver, or heart problems, inform your doctor before taking DEXLANSOPRAZOLE+DOMPERIDONE. Drive only if you are alert after taking DEXLANSOPRAZOLE+DOMPERIDONE. 

Uses of DEXLANSOPRAZOLE+DOMPERIDONE

Gastroesophageal reflux disease (GERD)

Medicinal Benefits

DEXLANSOPRAZOLE+DOMPERIDONE belongs to the class of drugs called gastrointestinal agents. It contains Dexlansoprazole and Domperidone.  Dexlansoprazole reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, it provides relief from heartburn symptoms related to acid reflux. Domperidone increases muscle movements and contractions in the stomach. Thereby, it prevents vomiting and reduces bloating, nausea and fullness. Also, it prevents reflux (regurgitation of the stomach contents back into the foodpipe).

Directions for Use

Take it on an empty stomach or as advised by your doctor. Swallow it with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DEXLANSOPRAZOLE+DOMPERIDONE

  • Diarrhoea
  • Nausea
  • Vomiting
  • Dry mouth
  • Stomach pain
  • Common cold
  • Gas

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to Domperidone, Dexlansoprazole or any other ingredients in DEXLANSOPRAZOLE+DOMPERIDONE, please tell your doctor. If you are pregnant or breastfeeding, please inform your doctor before taking DEXLANSOPRAZOLE+DOMPERIDONE. If you have a prolactinoma (tumour of the pituitary gland), liver, or heart problems, inform your doctor before taking DEXLANSOPRAZOLE+DOMPERIDONE. Drive only if you are alert after taking DEXLANSOPRAZOLE+DOMPERIDONE. If you experience heart rhythm disorders like difficulty in breathing, loss of consciousness, or palpitations (strong or irregular heartbeat) while taking DEXLANSOPRAZOLE+DOMPERIDONE, contact your doctor immediately. Dexlansoprazole in DEXLANSOPRAZOLE+DOMPERIDONE may increase the risk of severe diarrhoea. Therefore, if you have stomach pain, watery stool, and fever that does not go away, contact your doctor right away.

Drug Interactions

Drug-Drug Interaction: Inform your doctor if you are taking anti-HIV drugs (atazanavir, saquinavir, ritonavir), antifungals (ketoconazole, itraconazole, voriconazole), anticancer drugs (methotrexate, vandetanib, toremifene, vincamine), heart-related medicine (digoxin), a blood thinner (warfarin), an antibiotic containing ampicillin, a product that contains iron, immunosuppressant (tacrolimus), antibiotics (moxifloxacin, clarithromycin, telithromycin, erythromycin, levofloxacin), drugs for heart problems or high blood pressure (quinidine, amiodarone, disopyramide, sotalol, dofetilide), antipsychotic drugs (sertindole, pimozide, haloperidol), antidepressants (escitalopram, citalopram), drugs for gastrointestinal disorders (prucalopride, cisapride, dolasetron), antimalarial drugs (halofantrine) and anti-allergic drugs (mizolastine, mequitazine).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: If you have low or high magnesium levels in the blood, a prolactinoma (tumour of the pituitary gland), blocked or perforated gut, stomach bleeding, kidney, liver, or heart problems, inform your doctor before taking DEXLANSOPRAZOLE+DOMPERIDONE.

Drug-Drug Interactions Checker List:

  • ATAZANAVIR
  • SAQUINAVIR
  • RITONAVIR
  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • METHOTREXATE
  • VANDETANIB
  • TOREMIFENE
  • VINCAMINE
  • DIGOXIN
  • WARFARIN
  • TACROLIMUS
  • MOXIFLOXACIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ERYTHROMYCIN
  • LEVOFLOXACIN
  • QUINIDINE
  • AMIODARONE
  • DISOPYRAMIDE
  • SOTALOL
  • DOFETILIDE
  • SERTINDOLE
  • PIMOZIDE
  • HALOPERIDOL
  • ESCITALOPRAM
  • CITALOPRAM
  • PRUCALOPRIDE
  • CISAPRIDE
  • DOLASETRON
  • HALOFANTRINE
  • MIZOLASTINE
  • MEQUITAZINE
  • Safety Advice

    • Safety Warning

      Alcohol

      consult your doctor

      The interaction of DEXLANSOPRAZOLE+DOMPERIDONE with alcohol is unknown. If you have any concerns, discuss them with your doctor.

    • Safety Warning

      Pregnancy

      consult your doctor

      If you are pregnant or planning pregnancy, please consult your doctor before taking DEXLANSOPRAZOLE+DOMPERIDONE.

    • Safety Warning

      Breast Feeding

      consult your doctor

      If you are a breastfeeding mother, please inform your doctor before taking DEXLANSOPRAZOLE+DOMPERIDONE.

    • Safety Warning

      Driving

      consult your doctor

      If you have any concerns regarding the effect of DEXLANSOPRAZOLE+DOMPERIDONE on driving, please discuss it with your doctor.

    • Safety Warning

      Liver

      consult your doctor

      Consult your doctor before taking DEXLANSOPRAZOLE+DOMPERIDONE if you have any liver problems.

    • Safety Warning

      Kidney

      consult your doctor

      Consult your doctor before taking DEXLANSOPRAZOLE+DOMPERIDONE if you have any kidney problems.

    • Safety Warning

      Children

      consult your doctor

      If you have any concerns regarding the use of DEXLANSOPRAZOLE+DOMPERIDONE for children, please consult a doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat smaller meals more often.
    • Maintain a healthy weight by regular exercising.
    • Avoid lying down after eating as it causes acid reflux.
    • Avoid tight-fitting clothes as it might increase the pressure on the abdomen, leading to acid reflux.
    • Practice relaxation techniques and avoid stress by doing yoga or meditation.
    • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
    • Avoid sitting continuously, as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.
    • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

    Patients Concern

    Disease/Condition Glossary

    Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets irritated or eroded, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid repeatedly flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, difficulty swallowing and a sour or bitter taste in the mouth. 

    FAQs

    How does DEXLANSOPRAZOLE+DOMPERIDONE work?

    DEXLANSOPRAZOLE+DOMPERIDONE contains Dexlansoprazole and Domperidone. Dexlansoprazole reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe. Thus, it provides relief from heartburn symptoms related to acid reflux. Domperidone increases muscle movements and contractions in the stomach. Also, it prevents reflux (regurgitation of the stomach contents back into the foodpipe).

    Does DEXLANSOPRAZOLE+DOMPERIDONE cause dry mouth?

    DEXLANSOPRAZOLE+DOMPERIDONE may cause dry mouth as a temporary side effect. It is not necessary for everyone taking DEXLANSOPRAZOLE+DOMPERIDONE to experience this side effect. To avoid such side effects, practice good oral hygiene, drink plenty of water, regularly rinse your mouth, and suck on sugarless candy. However, please consult a doctor if the condition persists or worsens.

    Is DEXLANSOPRAZOLE+DOMPERIDONE safe for patients suffering from kidney problems?

    DEXLANSOPRAZOLE+DOMPERIDONE should be used with caution in patients suffering from kidney problems. Therefore, inform your doctor if you have any kidney problems before taking DEXLANSOPRAZOLE+DOMPERIDONE so that the dose may be adjusted appropriately.

    Available Medicines for

    DEXLANSOPRAZOLE+DOMPERIDONE