Do not take DICLOFENAC+TRAMADOL if you are allergic to NSAIDs, diclofenac, tramadol, or any of the ingredients of DICLOFENAC+TRAMADOL. Consumption of alcohol should be avoided during the treatment with DICLOFENAC+TRAMADOL as it may lead to increased risk of liver damage. Patients with stomach ulcers, gastric bleeding, severe heart failure, high blood pressure, and liver or kidney disease should not take DICLOFENAC+TRAMADOL. DICLOFENAC+TRAMADOL contains diclofenac, a category D pregnancy drug, so it is not recommended that you take DICLOFENAC+TRAMADOL during pregnancy as it may cause fetal deformities. While DICLOFENAC+TRAMADOL may pass in the lactating mother's breast milk, there is not enough evidence to establish the safety of DICLOFENAC+TRAMADOL in nursing mothers. So, it is advisable to take it only if prescribed by your doctor. If you have a severe allergy to painkillers and have conditions like asthma, rhinitis, angioedema (swelling under the skin), or skin rashes, immediately stop taking DICLOFENAC+TRAMADOL.

Drug-Drug Interactions: DICLOFENAC+TRAMADOL is known to interact with painkillers (nimesulide, oxyphenbutazone), blood clotting agents (warfarin), blood pressure-lowering agents (hydrochlorothiazide), medicines for depression (lithium), antifungals (itraconazole, voriconazole),  benzodiazepines (alprazolam, diazepam, estazolam, flurazepam, lorazepam, triazolam),  antibiotics (erythromycin), HIV medications (indinavir, nelfinavir, ritonavir) and medicines used to treat abnormal heart rhythms (quinidine).

Drug-Food Interactions: DICLOFENAC+TRAMADOL should not be taken along with St. John's Wort plant (a natural remedy to treat depression).

Drug-Disease Interactions: People with peptic ulcers, gastric bleeding, severe heart failure, diarrhoea and high blood pressure should avoid intake of DICLOFENAC+TRAMADOL as it may lead to life-threatening conditions.

• Include more glucosamine, chondroitin sulphate, vitamin D, and calcium-enriched supplements. Besides this, turmeric and fish oils can help in reducing inflammation in the tissue.
• Please do not go for heavy exercise as it may increase your joint pain in arthritis. Instead, you can do stretching, and low-impact aerobic exercises like walking on a treadmill, bike riding, and swimming. You can also strengthen your muscle strength by lifting light weights.
• In a chronic condition of arthritis or joint pain, including fish like salmon, trout, tuna and sardines. These fishes are enriched with omega-3 fatty acids that minimize cytokine's levels, which ramp up inflammation.
• Your sitting posture is important, especially when you have pain and inflammation conditions. Try to sit as little as possible and only for a short time (10-15 min). Use back support like a rolled-up towel at the back of your curve to minimize pain. Keep your knees and hips at a right angle. Besides this, you can use a footrest if required.

• DICLOFENAC+TRAMADOL tends to cause stomach upset. Thus, it is recommended to consume DICLOFENAC+TRAMADOL with meals to minimize gastric side effects. If you have a peptic ulcer diagnosis, DICLOFENAC+TRAMADOL is best avoided unless prescribed by your doctor.
• DICLOFENAC+TRAMADOL can cause liver injury when taken in large doses. Concomitant use of alcohol is best avoided as it aggravates liver toxicity.
• Although it is generally a safe medicine to use, it should be avoided in patients with kidney disease as DICLOFENAC+TRAMADOL may harm renal functions.
• DICLOFENAC+TRAMADOL contains Tramadol, which is a habit-forming drug. So, it should be taken for a short duration to avoid unpleasant withdrawal symptoms like breathing difficulties.
• Although DICLOFENAC+TRAMADOL provides symptomatic relief in conditions like arthritis and may reduce the inflammation caused by these conditions, to achieve the best results, it is strongly recommended to remain physically active as much as your condition allows. Adopting a healthy lifestyle coupled with a healthy diet containing high proteins is the mainstay of managing arthritic conditions.