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About DOMPERIDONE+MAGALDRATE+SIMETHICONE

DOMPERIDONE+MAGALDRATE+SIMETHICONE belongs to a group of medicines called gastrointestinal agents used to treat acidity, heartburn and gas. The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity and heartburn. Bloating occurs when the abdomen is filled with gas or air.
 
DOMPERIDONE+MAGALDRATE+SIMETHICONE contains Domperidone (prokinetic), Magaldrate (antacid), and Simethicone (anti-flatulent). Domperidone allows the food to move easily by increasing the movements of the stomach and intestine. Magaldrate works by neutralising excess stomach acid. Simethicone works by lowering the surface tension of gas bubbles, thereby facilitating the expulsion of gas through flatus or belching (burping). It also prevents the accumulation and formation of gas in the digestive tract. Together, DOMPERIDONE+MAGALDRATE+SIMETHICONE helps in treating acidity, heartburn and gas.
 
Take DOMPERIDONE+MAGALDRATE+SIMETHICONE as prescribed. You are advised to take DOMPERIDONE+MAGALDRATE+SIMETHICONE for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience common side-effects such as constipation, diarrhoea, bad taste, and dry mouth. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Avoid taking aluminium and magnesium-containing antacids with DOMPERIDONE+MAGALDRATE+SIMETHICONE. Aluminium-containing antacids, along with DOMPERIDONE+MAGALDRATE+SIMETHICONE could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea. Consult your doctor if you are pregnant or breastfeeding. DOMPERIDONE+MAGALDRATE+SIMETHICONE may cause sleepiness, so drive with caution. DOMPERIDONE+MAGALDRATE+SIMETHICONE is not recommended for use in children. Avoid consuming alcohol along with DOMPERIDONE+MAGALDRATE+SIMETHICONE as it could lead to increased acidity. 

Uses of DOMPERIDONE+MAGALDRATE+SIMETHICONE

Acidity, heartburn, gas

Medicinal Benefits

DOMPERIDONE+MAGALDRATE+SIMETHICONE is a combination of three drugs: Domperidone, Magaldrate, and Simethicone. DOMPERIDONE+MAGALDRATE+SIMETHICONE belongs to a group of medicines called gastrointestinal agents used to treat acidity, heartburn, and gas. Domperidone is a prokinetic that allows food to move easily by increasing the movements of the stomach and intestine. Magaldrate is an antacid that works by neutralising excess stomach acid. Simethicone is an anti-flatulent that works by lowering the surface tension of gas bubbles, thereby facilitating the expulsion of gas through flatus or belching (burping). It also prevents the accumulation and formation of gas in the digestive tract. Together, DOMPERIDONE+MAGALDRATE+SIMETHICONE helps in treating acidity, heartburn and gas.

Directions for Use

Tablet: Swallow the tablet as a whole with water; do not crush or chew it. Oral liquid/Suspension/Gel: Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DOMPERIDONE+MAGALDRATE+SIMETHICONE

  • Constipation
  • Diarrhoea
  • Bad taste
  • Dry mouth

In-Depth Precautions and Warning

Drug Warnings

Do not take DOMPERIDONE+MAGALDRATE+SIMETHICONE if you are allergic to any of its contents; if you have bleeding problems, blockage in intestines, a tumour of the pituitary gland, phenylketonuria, or high potassium levels in the blood. Inform your doctor if you have a history of heart, liver or kidney problems; if you are on a low-magnesium diet, or if you have undergone recent bowel surgery. Avoid taking aluminium and magnesium-containing antacids with DOMPERIDONE+MAGALDRATE+SIMETHICONE. Aluminium-containing antacids with DOMPERIDONE+MAGALDRATE+SIMETHICONE could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea. Consult your doctor if you are pregnant or breastfeeding. DOMPERIDONE+MAGALDRATE+SIMETHICONE may cause sleepiness, so drive with caution. DOMPERIDONE+MAGALDRATE+SIMETHICONE is not recommended for children.

Drug Interactions

Drug-Drug Interactions: DOMPERIDONE+MAGALDRATE+SIMETHICONE may interact with pain killers (aspirin), anti-hypertensive (ramipril), hormones (levothyroxine), anti-convulsant (phenytoin), antacids (aluminium hydroxide, magnesium hydroxide), anti-fungal (ketoconazole, fluconazole, voriconazole), antibiotics (erythromycin, clarithromycin, telithromycin, moxifloxacin, pentamidine), anti-depressant (escitalopram, citalopram).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform your doctor if you have bleeding problems, blockage in the intestines, a tumour of the pituitary gland, phenylketonuria, or high potassium levels in the blood.

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • RAMIPRIL
  • LEVOTHYROXINE
  • PHENYTOIN
  • ALUMINIUM HYDROXIDE
  • MAGNESIUM HYDROXIDE
  • KETOCONAZOLE
  • FLUCONAZOLE
  • VORICONAZOLE
  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • MOXIFLOXACIN
  • PENTAMIDINE
  • ESCITALOPRAM
  • CITALOPRAM
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking DOMPERIDONE+MAGALDRATE+SIMETHICONE as it may lead to increased sleepiness. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor before taking DOMPERIDONE+MAGALDRATE+SIMETHICONE if you are pregnant. Your doctor will prescribe DOMPERIDONE+MAGALDRATE+SIMETHICONE only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor before taking DOMPERIDONE+MAGALDRATE+SIMETHICONE; your doctor will decide whether DOMPERIDONE+MAGALDRATE+SIMETHICONE can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      DOMPERIDONE+MAGALDRATE+SIMETHICONE may cause sleepiness. Drive or operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Consult your doctor before taking DOMPERIDONE+MAGALDRATE+SIMETHICONE if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Consult your doctor before taking DOMPERIDONE+MAGALDRATE+SIMETHICONE if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      caution

      DOMPERIDONE+MAGALDRATE+SIMETHICONE is not recommended for use in children. Please consult your doctor if you have any concerns.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat smaller meals more often.
    • Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
    • Avoid lying down after eating to prevent acid backflow.
    • Avoid tight-fitting clothes as it might increase the pressure on the abdomen leading to acid reflux.
    • Maintain a healthy weight by regular exercising.
    • Practise relaxation techniques and avoid stress by doing yoga or meditation.
    • Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda. 
    • Avoid sitting continuously as it may trigger acidity. Take a break of 5 minutes every hour by doing brisk walking or stretching.

    Patients Concern

    Disease/Condition Glossary

    The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like acidity. Due to this, acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. Bloating occurs when the abdomen is filled with gas or air. Flatulence occurs when gas collects inside the digestive system.

    FAQs

    How does DOMPERIDONE+MAGALDRATE+SIMETHICONE work?

    DOMPERIDONE+MAGALDRATE+SIMETHICONE contains Domperidone, Magaldrate, and Simethicone. Domperidone allows the food to move easily by increasing the movements of the stomach and intestine. Magaldrate works by neutralising excess stomach acid. Simethicone lowers the surface tension of gas bubbles, thereby facilitating gas expulsion through flatus or belching (burping). It also prevents the accumulation and formation of gas in the digestive tract. Together, DOMPERIDONE+MAGALDRATE+SIMETHICONE helps in treating acidity, heartburn and gas.

    Does DOMPERIDONE+MAGALDRATE+SIMETHICONE cause dry mouth?

    Dry mouth could be a side-effect of DOMPERIDONE+MAGALDRATE+SIMETHICONE. Limiting caffeine intake, avoiding smoking, drinking water regularly and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

    Does DOMPERIDONE+MAGALDRATE+SIMETHICONE cause diarrhoea?

    Diarrhoea might be a side-effect of DOMPERIDONE+MAGALDRATE+SIMETHICONE. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

    Can I stop taking DOMPERIDONE+MAGALDRATE+SIMETHICONE on my own?

    To treat your condition effectually, continue taking DOMPERIDONE+MAGALDRATE+SIMETHICONE for as long as your doctor has prescribed. Speak with your doctor if you experience any difficulty while taking DOMPERIDONE+MAGALDRATE+SIMETHICONE.

    Does lying down immediately after having meals aggravate acidity?

    Avoid lying down immediately after meals to prevent acidity. Raise the head of the bed 10-20cm by putting a pillow so that the head and chest are above the waist. This prevents acid reflux.

    Can I take antacids along with DOMPERIDONE+MAGALDRATE+SIMETHICONE?

    Avoid taking aluminium and magnesium-containing antacids with DOMPERIDONE+MAGALDRATE+SIMETHICONE. Aluminium-containing antacids, along with DOMPERIDONE+MAGALDRATE+SIMETHICONE could lead to constipation and intestinal obstruction, whereas magnesium-containing antacids might cause diarrhoea.

    Available Medicines for

    DOMPERIDONE+MAGALDRATE+SIMETHICONE