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About DROTAVERINE+MEFENAMIC ACID

DROTAVERINE+MEFENAMIC ACID is a combination medicine used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.

DROTAVERINE+MEFENAMIC ACID is a combination of two drugs: Drotaverine (anti-spasmodic) and Mefenamic acid (NSAID). Drotaverine works by reducing calcium reuptake by the cells, thereby correcting the body's calcium levels and relieving contractions associated with smooth muscles. Mefenamic acid works by blocking the effect of chemical messengers that cause pain and inflammation at the injured or damaged site. Together, DROTAVERINE+MEFENAMIC ACID helps in relieving pain.

You are advised to take DROTAVERINE+MEFENAMIC ACID for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side-effects such as gastrointestinal disturbances, feeling thirsty, nausea, vomiting, diarrhoea, dry mouth, rashes and itching. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Inform your doctor if you have/had asthma, peptic ulcers, porphyria, or bleeding problems. Consult your doctor if you are pregnant or breastfeeding. DROTAVERINE+MEFENAMIC ACID may cause dizziness, so drive with caution. DROTAVERINE+MEFENAMIC ACID should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol as it could lead to increased drowsiness and dizziness; it might also increase stomach bleeding risk. Keep your doctor informed about your health condition and medicines to rule out any side-effects.

Uses of DROTAVERINE+MEFENAMIC ACID

Pain relief

Medicinal Benefits

DROTAVERINE+MEFENAMIC ACID is a combination of two drugs, namely: Drotaverine and Mefenamic acid. DROTAVERINE+MEFENAMIC ACID is used to treat abdominal pain, muscle pain, migraine headache, functional bowel disorders, dysmenorrhea (menstrual cramps), heavy bleeding during periods, renal colic pain, and pain after surgery. Drotaverine is an antispasmodic that reduces calcium reuptake by the cells, thereby correcting the calcium levels in the body and relieving contractions associated with smooth muscles. Mefenamic acid is an NSAID which works by blocking the effect of a chemical messenger in the body, known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, DROTAVERINE+MEFENAMIC ACID helps in relieving pain.

Directions for Use

Take DROTAVERINE+MEFENAMIC ACID with food to prevent stomach upset. Swallow DROTAVERINE+MEFENAMIC ACID as a whole with a glass of water; do not chew or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of DROTAVERINE+MEFENAMIC ACID

  • Gastrointestinal disturbances
  • Feeling thirsty
  • Nausea
  • Vomiting
  • Diarrhoea
  • Dry mouth
  • Rashes
  • Itching

In-Depth Precautions and Warning

Drug Warnings

Do not take DROTAVERINE+MEFENAMIC ACID if you are allergic to any of its contents. Inform your doctor if you have severe heart failure, or have suffered bleeding problems such as bleeding from the stomach or bowels while taking any painkillers. If you have had any recent heart surgery, do not take DROTAVERINE+MEFENAMIC ACID unless prescribed by the doctor, as DROTAVERINE+MEFENAMIC ACID may increase the risk of heart attack or stroke. Inform your doctor if you have/had asthma, peptic ulcers, porphyria, bleeding problems, liver or kidney impairment. Consult your doctor if you are pregnant or breastfeeding. DROTAVERINE+MEFENAMIC ACID may cause dizziness, so drive only if you are alert. DROTAVERINE+MEFENAMIC ACID should not be given to children as safety has not been established. Avoid consuming alcohol as it could lead to increased drowsiness and may increase the risk of stomach bleeding. Stop taking DROTAVERINE+MEFENAMIC ACID and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with DROTAVERINE+MEFENAMIC ACID unless prescribed.

Drug Interactions

Drug-Drug Interactions: DROTAVERINE+MEFENAMIC ACID may interact with pain killers (aspirin, ibuprofen, celecoxib), anticoagulants (warfarin), anti-Parkinson's (levodopa), immunosuppressants (cyclosporine, tacrolimus), anti-gout (probenecid), anti-depressant (duloxetine, lithium, fluoxetine, sertraline), cardiac glycosides (digoxin), anti-rheumatoid (methotrexate), anti-HIV (zidovudine), and antiprogestational steroids (mifepristone).

Drug-Food Interactions: Avoid alcohol consumption while taking DROTAVERINE+MEFENAMIC ACID as it might cause increased dizziness and risk of stomach bleeding.

Drug-Disease Interactions: Inform your doctor if you have peptic ulcers, bleeding disorders, low blood pressure, diabetes, Crohn's disease, inflammatory bowel disease, heart, kidney or liver problems.

Drug-Drug Interactions Checker List:

  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • WARFARIN
  • LEVODOPA
  • CYCLOSPORINE
  • TACROLIMUS
  • PROBENECID
  • DULOXETINE
  • LITHIUM
  • FLUOXETINE
  • SERTRALINE
  • DIGOXIN
  • METHOTREXATE
  • ZIDOVUDINE
  • MIFEPRESTONE
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol while taking DROTAVERINE+MEFENAMIC ACID as it may cause increased drowsiness. It can also increase the risk of stomach bleeding.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor before taking DROTAVERINE+MEFENAMIC ACID if you are breastfeeding. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Driving

      caution

      DROTAVERINE+MEFENAMIC ACID may cause drowsiness. Drive or operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      Please consult your doctor if you have a liver impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Kidney

      caution

      Please consult your doctor if you have kidney impairment or any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Children

      unsafe

      DROTAVERINE+MEFENAMIC ACID should not be given to children as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
    • Massages can also be helpful.
    • Avoid freezing and hot temperatures.
    • Avoid wearing tight-fitting clothes; instead, wear loose garments.
    • Rest well, and get plenty of sleep.
    • To avoid developing pressure sores, change your position at least every two hours.
    • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot-pack on the muscle for 15-20minutes.
    • Stay hydrated, drink plenty of water.

    Patients Concern

    Disease/Condition Glossary

    Pain: It is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Pain may be dull or sharp; it might be constant or may come and go. The common causes of pain include headache, muscle strain, cramps, cuts, bone fractures, arthritis, and stomach ache. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

    FAQs

    How does DROTAVERINE+MEFENAMIC ACID work?

    DROTAVERINE+MEFENAMIC ACID contains Drotaverine and Mefenamic acid. Drotaverine works by relieving contractions associated with smooth muscles of the abdomen. Mefenamic acid works by blocking the action of certain chemical messengers that cause pain.

    Does DROTAVERINE+MEFENAMIC ACID cause diarrhoea?

    Diarrhoea might be a side-effect of DROTAVERINE+MEFENAMIC ACID. Drink enough fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you experience severe diarrhoea or if you find blood in your stools.

    How to cope with dry mouth?

    Dry mouth could be a side-effect of DROTAVERINE+MEFENAMIC ACID. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

    Can I take DROTAVERINE+MEFENAMIC ACID for longer durations?

    Do not take DROTAVERINE+MEFENAMIC ACID for longer durations as it might increase the risk of heart problems and stomach bleeding. Take DROTAVERINE+MEFENAMIC ACID only for as long as your doctor has prescribed it.

    Can I stop taking DROTAVERINE+MEFENAMIC ACID if I feel well?

    DROTAVERINE+MEFENAMIC ACID is generally prescribed for short durations and can be discontinued after pain relief. However, you are advised to continue taking DROTAVERINE+MEFENAMIC ACID for as long as your doctor has prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking DROTAVERINE+MEFENAMIC ACID.

    Is DROTAVERINE+MEFENAMIC ACID used to treat period pain?

    DROTAVERINE+MEFENAMIC ACID is used to treat dysmenorrhea (period pain), pain due to heavy bleeding during periods, and menstrual cramps. Take DROTAVERINE+MEFENAMIC ACID only as prescribed, and do not overdose.

    Available Medicines for

    DROTAVERINE+MEFENAMIC ACID