Dapoxetine
About Dapoxetine
Dapoxetine is used to treat premature ejaculation in adult men. Premature ejaculation is when a man ejaculates (orgasms) more quickly with less sexual stimulation than the man or his partner would like.
Dapoxetine contains Dapoxetine, which increases serotonin levels in the nervous system; this increases the time it takes to ejaculate and improves control over ejaculation. Thus, it helps in reducing the worry or frustration about premature ejaculation.
Take Dapoxetine 1-3 hours before sexual activity or follow your doctor’s advice. Swallow it whole with a glass of water, without crushing or chewing. Some common side effects include dizziness, headache, nausea, diarrhoea, dry mouth, and indigestion. Talk to your doctor if you experience these side effects persistently.
Dapoxetine should not be used by men under 18 years or over 65 years. It is not intended for use in women. Keep your doctor informed about your health condition and any medicines you are taking to avoid unpleasant side effects.
Uses of Dapoxetine
• Premature ejaculation: Dapoxetine is used to treat premature ejaculation in men. It helps delay ejaculation and improve control over ejaculation, allowing for a more satisfying sexual experience.
• Improved Sexual Confidence: Dapoxetine makes the users feel more confident in their sexual performance by addressing challenges related to premature ejaculation.
• Enhanced Stamina and Duration: Dapoxetine may also be involved in prolonging the duration of sexual intercourse, leading to improved sexual satisfaction for both partners.
• Stress and Anxiety Reduction: Dapoxetine can reduce anxiety or stress related to sexual performance, improving sexual performance.
• Restoration of Intimacy: Dapoxetine can help restore intimacy in erectile dysfunction relationships, resulting in a stronger emotional connection between partners.
Medicinal Benefits
- Dapoxetine is used in the treatment of premature ejaculation.
- It helps increase the time it takes to ejaculate and improve control over ejaculation.
- It may help prolong the duration of intercourse, leading to improved sexual satisfaction for both partners.
- It may ease anxiety or stress related to premature ejaculation, improving the overall sexual experience.
- It can help restore intimacy in relationships affected by premature ejaculation, helping partners feel more emotionally connected.
Directions for Use
- Dapoxetine can be taken with or without food.
- It is recommended to take Dapoxetine 1-3 hours before sexual activity or as advised by your doctor.
- Do not take Dapoxetine more than once every 24 hours.
- Swallow Dapoxetine as a whole with a glass of water to avoid a bitter taste.
- Do not crush, chew, or break it.
Storage
Side Effects of Dapoxetine
- Dizziness
- Headache
- Nausea
- Diarrhoea
- Dry mouth
- Indigestion
Drug Warnings
- Do not take Dapoxetine if you are allergic to any of its contents.
- Inform your doctor before taking Dapoxetine if you have a history of dizziness due to low blood pressure, mania, depression, schizophrenia, seizures, bleeding or blood clotting problems, glaucoma, or heart/liver/kidney problems.
- Avoid consuming alcohol, as it may cause increased dizziness.
- Dapoxetine may cause dizziness, sleepiness, fainting, or blurred vision, so drive with caution.
- Rise slowly from a sitting or lying position, as Dapoxetine may cause dizziness on standing up suddenly.
- Dapoxetine is not recommended for children under 18 years of age, as its safety and effectiveness have not been established.
Drug Interactions
Drug-Drug Interactions: Dapoxetine may interact with certain medicines, potentially increasing side effects. Inform your doctor if you are taking any of the following:
- Drugs used for schizophrenia and other psychotic disorders (thioridazine)
• Potential effect: May cause serious heart rhythm issues such as QT prolongation. - Anti-psychotics (lithium)
• Potential effect: May increase the risk of serotonin syndrome (a serious reaction caused by excess serotonin in the body). - Antibiotics (linezolid)
• Potential effect: May increase the serum concentration of dapoxetine and the risk of serotonin syndrome. - Amino acids (tryptophan)
• Potential effect: May increase the risk of serotonin syndrome. - Painkillers (aspirin)
• Potential effect: May increase the risk of bleeding. - Anti-HIV drugs (ritonavir, saquinavir)
• Potential effect: May increase the serum concentration of dapoxetine and the risk of side effects. - Antifungals (ketoconazole, itraconazole)
• Potential effect: May increase the serum concentration of dapoxetine and the risk of side effects. - Antidepressants (nefazodone)
• Potential effect: May increase the risk of serotonin syndrome. - Blood thinners (warfarin)
• Potential effect: May increase the risk of bleeding. - Drugs used for hypertension (diltiazem, verapamil)
• Potential effect: May increase the serum concentration of dapoxetine and the risk of low blood pressure or fainting. - Antiemetics (aprepitant)
• Potential effect: May increase the serum concentration of dapoxetine and the risk of side effects.
Drug-Food Interactions:
- Do not take St. John’s wort (an herbal supplement used to treat depression) while taking Dapoxetine.
- Avoid consuming grapefruit juice within 24 hours of taking Dapoxetine, as it could lead to an increase in the level of Dapoxetine in the body.
Drug-Disease Interactions:
Dapoxetine should be used with caution in people with:
- A history of dizziness due to low blood pressure
- Mental health conditions such as depression, mania, bipolar disorder, or schizophrenia
- Epilepsy (seizures/fits)
- Bleeding or blood-clotting problems
- Glaucoma (increased eye pressure)
- Heart, liver, or kidney problems.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consuming alcohol while taking Dapoxetine, as it might cause increased dizziness and sleepiness.
Pregnancy
unsafeDapoxetine is not intended for use in women.
Breast Feeding
unsafeDapoxetine is not intended for use in women.
Driving
cautionDapoxetine may cause dizziness, sleepiness, fainting, or blurred vision. Therefore, you are advised to drive and operate machinery only if you are alert.
Liver
cautionDapoxetine should not be taken if you have moderate to severe liver problems. Please consult your doctor before taking Dapoxetine if you have liver disease or any concerns regarding this.
Kidney
cautionDose adjustment may be needed. Please consult your doctor before taking Dapoxetine if you have kidney impairment/kidney disease or any concerns regarding this.
Children
unsafeDapoxetine is not recommended for use in children below 18 years, as its safety and effectiveness have not been established.
Habit Forming
Diet & Lifestyle Advise
Healthy habits:
- Maintaining a healthy weight, eating a balanced diet, and exercising regularly may help manage premature ejaculation.
- Regular sexual activity may help prevent future issues.
Exercise:
- Try pelvic floor exercises to strengthen your supporting muscles.
- Practice relaxation techniques to help reduce stress.
Dietary recommendations:
- Eat foods that help improve blood flow, such as onions, garlic, bananas, chilli, eggs, omega-3 fatty acids, vitamin B1, and pepper.
Sexual Practices:
- Use condoms to help reduce the sensitivity of the penis.
- Spend intimate time with your partner to strengthen your emotional connection.
Lifestyle measures:
- Avoid smoking and alcohol consumption.
- Get enough sunlight exposure, as it may increase melatonin and support sexual desire.
Special Advise
- Dapoxetine has a bitter taste, so take it with at least one full glass of water. This also helps in lowering the chance of fainting.
- Take Dapoxetine 1-3 hours before sexual activity.
- Do not take more than one tablet in a day (24 hours).
Patients Concern
Disease/Condition Glossary
Premature ejaculation: Premature ejaculation happens when a man ejaculates (orgasms) more quickly with less sexual stimulation than the man or his partner would like. This could lead to problems in a sexual relationship. Possible causes include low self-esteem, depression, a history of sexual abuse, anxiety about performance or limited sexual experience, stress, dissatisfaction, or relationship issues.
FAQs
Dapoxetine is used to treat premature ejaculation in adult men.
Dapoxetine works by increasing the time it takes to ejaculate and improving control over ejaculation. Thereby, it helps in reducing the worry or frustration about fast or premature ejaculation.
Medicines such as monoamine oxidase inhibitors (MAOI), thioridazine (used to treat schizophrenia), lithium (used to treat mania), linezolid (antibiotic), tryptophan (used to help you sleep), tramadol (used to relieve pain), St. John’s wort (herbal supplement used to treat depression), anti-depressants, and anti-migraine medicines should not be taken along with Dapoxetine. Maintain a gap of 14 days before taking Dapoxetine if you have taken any of the above medicines. After taking Dapoxetine, maintain a gap of 7 days before taking these medicines. Talk to your doctor if you have any concerns regarding this.
You may experience sleeping problems and may feel dizzy if you stop taking Dapoxetine on your own. Therefore, consult your doctor before discontinuing the medicine.
Do not take Dapoxetine for longer durations unless prescribed by the doctor. Discuss with your doctor after the first 4 weeks or after taking 6doses if you should continue the treatment. If Dapoxetine has been prescribed for longer durations, regular consultation with the doctor is advised every 6 months.
Dry mouth could be a side effect of Dapoxetine. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.
Orthostatic hypotension could be a side effect of Dapoxetine. Orthostatic hypotension is a sudden lowering in blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead, lie down and get up slowly only when you feel better.
Dapoxetine contains Dapoxetine, which increases the serotonin level in the nervous system; this increases the time it takes to ejaculate and improves the control over ejaculation.
Dapoxetine, the first drug developed for premature ejaculation, is an effective and safe treatment for premature ejaculation and represents a significant advance in sexual medicine.
Yes, Dapoxetine is a prescription medication. It should be taken if prescribed by the doctor.
Treatment with Dapoxetine was generally safe and well-tolerated across the range of doses. Seek medical attention if you have any concerns.
Dapoxetine is an effective and safe treatment for premature ejaculation and represents a major advance in sexual medicine.
No, Dapoxetine usually does not cause any erectile dysfunction. If you experience this, please seek medical attention.
Yes, you can take it if prescribed by the healthcare professional. The combination is well tolerated.
Dapoxetine is not recommended for use in children below 18 years as safety and effectiveness have not been established.
Before using this medication, you should inform your doctor about your medical history, including any ongoing medicines, to avoid potential interactions and minimise side effects.
A dose adjustment may be needed. Please consult your doctor before taking Dapoxetine if you have kidney impairment or disease, or have any concerns regarding this.
Common side effects of Dapoxetine may include dizziness, headache, nausea, diarrhoea, dry mouth, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
