EVOGLIPTIN+METFORMIN belongs to the group of medications called 'antidiabetic agents' used as an adjunct to diet and exercise to improve glycaemic control in adult patients with type 2 diabetes mellitus. This medication improves glycaemic control in diabetic patients who do not react well to metformin alone. Type 2 diabetes mellitus is a chronic or life-long condition in which blood sugar or glucose levels rise more than normal.
EVOGLIPTIN+METFORMIN is a combination of two medicines: Metformin and Evogliptin. Metformin acts by decreasing liver glucose production and intestinal glucose uptake. On the other side, Evogliptin works by increasing insulin release from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces the fasting and post-meal sugar levels. Thereby, EVOGLIPTIN+METFORMIN reduces sugar levels in the body.
Take EVOGLIPTIN+METFORMIN as prescribed. You are advised to take EVOGLIPTIN+METFORMIN for as long as your doctor has advised. In some cases, EVOGLIPTIN+METFORMIN may cause nausea, vomiting, diarrhoea, headache, stomach ache, respiratory infection, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, if the side effects persist or worsen, consult your doctor.
Do not take EVOGLIPTIN+METFORMIN if you are allergic to any of its contents. EVOGLIPTIN+METFORMIN may cause lactic acidosis (accumulation of lactic acid in the blood), which requires immediate medical attention. The risk increases if you are previously diagnosed with kidney or liver diseases. Do not consume alcohol (risk of lactic acidosis) or fast for prolonged periods (risk of hypoglycaemia). Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Type 2 Diabetes Mellitus
EVOGLIPTIN+METFORMIN is indicated for managing type 2 diabetes with the right diet and exercise. EVOGLIPTIN+METFORMIN is a combination of two medicines: Metformin (biguanide) and Evogliptin (dipeptidyl peptidase-4 inhibitor). Metformin acts by decreasing liver glucose production and intestinal glucose uptake. Evogliptin works by increasing insulin release from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces fasting and post-meal sugar levels. Thereby, EVOGLIPTIN+METFORMIN reduces sugar levels in the body.
Do not take EVOGLIPTIN+METFORMIN if you are allergic to any of its contents. Do not use this medicine if you have heart failure, bladder cancer, or diabetic ketoacidosis (a complication of diabetes). EVOGLIPTIN+METFORMIN may cause lactic acidosis (accumulation of lactic acid in the blood), which requires immediate medical attention. The risk increases if you are previously diagnosed with kidney or liver diseases. Do not consume alcohol with EVOGLIPTIN+METFORMIN as it may increase the risk of lactic acidosis or fast for prolonged periods as it might increase the risk of hypoglycaemia. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
Drug-Drug Interactions: EVOGLIPTIN+METFORMIN may have interaction with antibiotic medicines (e.g. clarithromycin), steroid medicines ( e.g. prednisolone), diuretics medicines (e.g. furosemide), medicines to treat heart problems and high blood pressure (e.g. enalapril, perindopril), hormones (e.g. testosterone, oestrogen and progesterone) and other diabetes medicines.
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: EVOGLIPTIN+METFORMIN may interact with uncontrolled diabetes, liver/kidney/heart problems, severe infection, severe circulation problems or breathing difficulties.
It is advised to avoid alcohol intake since it may worsen the side effects like lactic acidosis and increase the risk of developing low blood sugar levels.
Limited information is available on the use of EVOGLIPTIN+METFORMIN in pregnant women. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.
Limited information on the use of EVOGLIPTIN+METFORMIN in breastfeeding mothers is available. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.
If your blood sugar is too low or too high, your driving ability may be affected. Do not drive if these symptoms appear.
There is limited information available on the use of EVOGLIPTIN+METFORMIN in patients with liver disease. Your doctor will weigh the benefits and any potential risks before prescribing them to you. Please consult your doctor.
Limited information is available on using EVOGLIPTIN+METFORMIN in patients with kidney disease. Your doctor will weigh the benefits and potential risks before prescribing them. Please consult your doctor.
EVOGLIPTIN+METFORMIN is not recommended for people younger than 18 years of age.
Type 2 diabetes mellitus: Type 2 diabetes mellitus is a chronic condition in which blood glucose levels are elevated in the body. Insulin is responsible for the utilization of glucose by the cells. In type 2 diabetes, the body cells do not respond to insulin; in later stages, your body may not produce enough insulin. Symptoms include excessive thirst, excessive hunger, fatigue, increased appetite and dry mouth. If not properly treated, this condition may worsen over time and cause toxic effects.