Fexuprazan
About Fexuprazan
Fexuprazan is used in the treatment of Erosive Esophagitis, and improvement of gastric mucosal lesions in acute or chronic gastritis. Erosive oesophagitis is a condition in which the oesophagus is damaged by harmful acid, leading to inflammation, scarring, and ulcers. The oesophagus is a tube that connects the mouth to the stomach.
Fexuprazan contains Fexuprazan, which works by lowering the amount of acid produced in the stomach.
In some cases, Fexuprazan may cause side effects such as diarrhoea, nausea, headache, constipation, myalgia, ear discomfort, abdominal discomfort, and a runny nose. Most of these side effects may not require medical attention. However, talk to the doctor if the side effects persist or worsen.
Let the doctor know if you are allergic to any components in Fexuprazan. Consult the doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions. Let your doctor know if you have any liver/kidney problems or are elderly in age before taking Fexuprazan.
Medicinal Benefits
- Fexuprazan is used to treat and manage heartburn and acid reflux.
- It helps heal and prevent ulcers in the stomach, oesophagus, and duodenum.
- It is indicated in the treatment of erosive esophagitis, a condition associated with excessive stomach acid production.
- By reducing acid production, Fexuprazan relieves symptoms of heartburn, acidity, and indigestion, and promotes ulcer healing.
- It helps prevent the recurrence of acid-related damage to the oesophagus and stomach lining.
- Fexuprazan provides relief from acid-related discomfort and supports digestive system healing and comfort.
Directions for Use
- Fexuprazan can be taken with or without food or as advised by your doctor.
- Fexuprazan is usually taken once a day (for erosive esophagitis) and twice a day (for acute or chronic gastritis), or as prescribed by your doctor.
- Swallow Fexuprazan as a whole with a glass of water.
- Do not break, crush or chew it.
Side Effects of Fexuprazan
- Diarrhoea
- Headache
- Nausea
- Abdominal discomfort
- Constipation
- Flatulence
- Rhinorrhoea (runny nose)
- Myalgia
Drug Warnings
- Do not take Fexuprazan if you are allergic to any of its contents.
- Inform your doctor if you have bleeding problems or liver or kidney impairment.
- This medicine is nt recommended for use in pregnant and breastfeeding mothers. Consult the doctor if you are pregnant, planning for pregnancy, or breastfeeding.
- Limited information is available regarding the usage of Fexuprazan in children, so if you have any concerns, talk to your doctor.
- Let the doctor know if you are taking any other medicines, including supplements or herbal products.
- Fexuprazan contains lactose in its composistion. Hence, avoid taking this medicine if you have any congenital conditions for lactose, such as galactose intolerance, Lactase deficiency or glucose-galactose malabsorption.
- Inform your physician about your complete medication including HIV medication, as it can cause adverse reactions.
Drug Interactions
Drug-Drug Interaction: Fexuprazan may interact with antiretroviral (Atazanavir, Nelfinavir), antiplatelet (Cilostazol, Clopidogrel), antifungals (Ketoconazole).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: Inform the doctor if you have hepatic/renal impairment.
Drug-Drug Interactions Checker List:
Safety Advice

Alcohol
consult your doctorIt is unknown if alcohol interacts with Fexuprazan. Please consult the doctor.

Pregnancy
unsafeFexuprazan is contraindicated for use in pregnant women. Hence please inform your physician if you are pregnant or planning for pregnancy.

Breast Feeding
unsafeFexuprazan is contraindicated for use in breastfeeding mothers. Hence please inform your physician if you are a breastfeeding mother.

Driving
consult your doctorIt is not known if Fexuprazan affects your ability to drive. Drive or operate machinery only if you are alert.

Liver
cautionFexuprazan should be used with caution in patients with liver disease. Consult the doctor before taking Fexuprazan if you have a liver impairment or any concerns regarding this

Kidney
cautionFexuprazan should be used with caution in patients with kidney disease. Consult the doctor before taking Fexuprazan if you have a kidney impairment or any concerns regarding this

Children
unsafeFexuprazan is not recommended for use in children below 16 years of age as the safety and efficacy are not established.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller meals more often.
- Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
- Avoid lying down after eating to prevent acid backflow.
- Avoid tight-fitting clothes, as it might increase the pressure on the abdomen, leading to acid reflux.
- Maintain a healthy weight by regularly exercising.
- Practice relaxation techniques and avoid stress by doing yoga or meditation.
- Avoid high-fat foods, spicy foods, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea and soda.
- Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by doing brisk walking or stretching.
Patients Concern
Disease/Condition Glossary
Erosive esophagitis: It occurs due to the reflux of gastric contents into the stomach, which leads to mucosal injury and damages the tissue lining the oesophagus.
FAQs
Fexuprazan is used in the treatment of Erosive Esophagitis, improvement of gastric mucosal lesions in acute or chronic gastritis.
Fexuprazan works by lowering the amount of acid produced in the stomach. Thereby, it provides relief from acidity-related conditions such as ulcers, gastritis, GERD, and dyspepsia.
To treat your condition effectually, continue taking Fexuprazan for as long as your doctor has prescribed. Speak with your doctor if you experience any difficulty while taking Fexuprazan.
Diarrhoea might be a side-effect of Fexuprazan. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If the condition persists or worsens, consult your doctor.
Fexuprazan may cause side effects such as diarrhoea, nausea, headache, constipation, myalgia, ear discomfort, abdominal discomfort, and runny nose

