About FLUCONAZOLE+IVERMECTIN
FLUCONAZOLE+IVERMECTIN is a combination medicine used to treat fungal infections and parasitic infections caused by certain parasites, such as head lice, scabies, and certain types of worms. FLUCONAZOLE+IVERMECTIN works by inhibiting fungal growth and multiplication and paralyzing and killing parasites.
FLUCONAZOLE+IVERMECTIN combines Fluconazole (antifungal) and Ivermectin (anthelmintics). Fluconazole kills fungi by causing holes in their cell membranes, allowing the contents to flow out. This treats the infection and allows your symptoms to subside. Ivermectin paralyzes and destroys the parasite or prevents adult parasites from creating larvae for a while. Thus, it effectively treats parasitic infections.
Take FLUCONAZOLE+IVERMECTIN as prescribed by your doctor. You are advised to take FLUCONAZOLE+IVERMECTIN for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience nausea, vomiting, rash, oedema, headache, dizziness, asthenia (weakness), diarrhoea, stomach pain and altered food tastes. Most of these side effects of FLUCONAZOLE+IVERMECTIN do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.
It is recommended not to use FLUCONAZOLE+IVERMECTIN if you are allergic to any ingredients in this formulation. Do not use FLUCONAZOLE+IVERMECTIN unless prescribed by the doctor, especially if you are a pregnant or nursing mother. You are recommended to complete the entire course of FLUCONAZOLE+IVERMECTIN as your doctor prescribes for effective results. FLUCONAZOLE+IVERMECTIN may cause drowsiness, or weakness at some times. Therefore, avoid driving if you experience any of these symptoms after taking FLUCONAZOLE+IVERMECTIN.
Uses of FLUCONAZOLE+IVERMECTIN
Fungal Infections and Parasitic Infections
Medicinal Benefits
FLUCONAZOLE+IVERMECTIN combines two drugs: fluconazole (antifungal) and ivermectin (anthelmintics). It is used to treat fungal infections and parasitic infections caused by certain parasites, such as head lice, scabies, and certain types of worms. Fluconazole kills or inhibits fungi and yeast by blocking an enzyme in fungi responsible for proper fat metabolism, resulting in the production of the fungal cell membrane. As a result, fungal or yeast cells are killed, or their growth is inhibited. Ivermectin paralyzes and kills the parasite or temporarily prevents adult parasites from producing larvae. Thus, it is helpful in treating parasite infections.
Directions for Use
Storage
Side Effects of FLUCONAZOLE+IVERMECTIN
- Nausea
- Vomiting
- Rash
- Edema
- Headache
- Dizziness
- Asthenia (weakness)
- Diarrhea
- Stomach pain
- Altered food tastes
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to FLUCONAZOLE+IVERMECTIN or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, you are advised not to use it unless instructed by the doctor. Drive only if you are alert, as FLUCONAZOLE+IVERMECTIN may cause drowsiness and weakness. Avoid alcohol consumption as alcohol impairs the immune system's ability to prepare for and defend against hazardous microorganisms, increasing the risk of serious illnesses. You are recommended to complete the full course of FLUCONAZOLE+IVERMECTIN as your doctor prescribes for effective results.
Drug Interactions
Drug-Drug Interaction: FLUCONAZOLE+IVERMECTIN may interact with certain benzodiazepines (e.g. alprazolam, triazolam), antiarrhythmics (e.g. amiodarone, dronedarone), antineoplastic agent (e.g. bosutinib), anti-cancer medications (e.g. Ceritinib), antiviral medications (e.g. efavirenz), antiallergic drugs (astemizole, terfenadine), antipsychotic drug (pimozide)
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: If you have liver or kidney impairment, QT prolongation or arrhythmias, inform your doctor before taking FLUCONAZOLE+IVERMECTIN.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionNo interaction was found. However, alcohol inhibits the immune system's ability to prepare and defend the body against hazardous microorganisms, increasing the risk of serious illnesses.
Pregnancy
cautionPlease consult the doctor. There are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionIt is unknown whether FLUCONAZOLE+IVERMECTIN is excreted in human milk. FLUCONAZOLE+IVERMECTIN is given to breastfeeding mothers if the doctor thinks the benefits outweigh the risks. Please consult a doctor if you are breastfeeding.
Driving
cautionFLUCONAZOLE+IVERMECTIN may cause drowsiness or asthenia (weakness). Therefore, avoid driving if you experience these symptoms after taking FLUCONAZOLE+IVERMECTIN.
Liver
cautionRegular liver function tests are recommended for patients with pre-existing liver issues, particularly if they are taking medication for an extended period of time. Treatment should be stopped if liver enzyme levels drop or stay high. Hence, if you have liver problems, inform your doctor before taking FLUCONAZOLE+IVERMECTIN.
Kidney
cautionDue to inadequate drug clearance, patients with renal impairment may be more vulnerable to fluconazole side effects. When taking the medication in multiple doses, patients with moderate to severe kidney impairment (CrCl <= 50 mL/min) should adjust their dosage. So, if you have kidney problems, inform your doctor before taking FLUCONAZOLE+IVERMECTIN.
Children
cautionLimited information about using FLUCONAZOLE+IVERMECTIN in children is available, so please consult a doctor if you have any concerns.
Habit Forming
Diet & Lifestyle Advise
- Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
- In wet places such as changing rooms and gym showers, don’t walk barefoot. Wear flip-flops or sandals to prevent fungal infections.
- Do not scratch the affected skin; it can spread the infection to other body parts.
- Avoid sharing towels, combs, bedsheets, shoes, or socks with others to prevent the spread of infection.
- Wash your bed sheets and towels regularly.
- Avoid getting in contact with harsh soaps, detergents, and rough fabrics.
Special Advise
- If the infection persists or worsens after using FLUCONAZOLE+IVERMECTIN for 1 week, please consult a doctor.
- If you experience diarrhea during the use of FLUCONAZOLE+IVERMECTIN, drink lots of water and consult your doctor, do not use any anti-diarrheal medicine on your own.
Patients Concern
Disease/Condition Glossary
Fungal infection: Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may affect the skin and spread into bones, tissues, organs, or the whole body. It may be contagious (spread from one person to another). The symptoms of a fungal infection include skin rash, darkening of the skin, peeling, itching, deformed toenail, or vaginal discharge. Antifungal medicines are usually used to treat fungal infections.
Parasitic infections: Parasitic worms, also called intestinal worms or helminths, are infections caused by parasites (micro-organisms) that live in or on another host/organism. These infections can occur due to consuming contaminated water, food or soil, contact with contaminated faeces, poor sanitisation and poor hygiene. Symptoms may include abdominal pain, diarrhoea, nausea, vomiting, gas, bloating, fatigue, unexplained weight loss, and dysentery (bloody stools). FLUCONAZOLE+IVERMECTIN is used in treating infections of the roundworms, hookworms, threadworms, whipworms, and pinworms.
