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About FLUCONAZOLE+ORNIDAZOLE

FLUCONAZOLE+ORNIDAZOLE belongs to a class of medication called anti-infectives used to treat various fungal and bacterial infections. Fungal infection is a skin disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another). A bacterial infection is a condition in which harmful bacteria grow in the body and cause infection. It can infect any part of the body and multiply very quickly.

FLUCONAZOLE+ORNIDAZOLE is a combination of two drugs, namely: Fluconazole (antifungal) and Ornidazole (antiprotozoal). The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Fluconazole belongs to the class of antifungals that works by damaging the fungal cell membranes and kills fungi. Ornidazole belongs to the class of antiprotozoals that works by damaging the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA. Thereby, kills micro-organisms and clears the infection.

Take FLUCONAZOLE+ORNIDAZOLE as prescribed by your doctor. You are advised to take FLUCONAZOLE+ORNIDAZOLE for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience vomiting, nausea, diarrhoea, headache, stomach discomfort or rash. Most of these side effects of FLUCONAZOLE+ORNIDAZOLE do not require medical attention and gradually resolve over time. However, if the side effects worsen or persist, please consult your doctor.

If you are allergic to FLUCONAZOLE+ORNIDAZOLE or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using FLUCONAZOLE+ORNIDAZOLE. Drive only if you are alert as FLUCONAZOLE+ORNIDAZOLE may cause drowsiness, dizziness, or light-headedness. Avoid alcohol consumption with FLUCONAZOLE+ORNIDAZOLE as it may cause adverse effects such as nausea, increased heartbeat, chest pain, thirst, flushing (reddening of the skin), or low blood pressure. You are recommended to complete the full course of FLUCONAZOLE+ORNIDAZOLE as prescribed by your doctor for effective results.

Uses of FLUCONAZOLE+ORNIDAZOLE

Fungal infections, Bacterial infections

Medicinal Benefits

FLUCONAZOLE+ORNIDAZOLE is a combination of two drugs, namely: Fluconazole and Ornidazole used to treat various fungal and bacterial infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Fluconazole is an antifungal that damages the fungal cell membranes and kills fungi. Ornidazole is an antiprotozoal that damages the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA. Thereby, killing micro-organisms and clearing the infection.

Directions for Use

Take FLUCONAZOLE+ORNIDAZOLE with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of FLUCONAZOLE+ORNIDAZOLE

  • Nausea
  • Headache
  • Skin rash
  • Vomiting
  • Abdominal pain
  • Diarrhea
  • Fatigue
  • Seizures
  • Myalgia
  • Abnormal taste
  • Tingling or numbness in the fingers or toes
  • Tremors
  • Sleepiness
  • Vertigo
  • Allergic skin reaction
  • Tiredness
  • Dizziness

In-Depth Precautions and Warning

Drug Warnings

If you are allergic to FLUCONAZOLE+ORNIDAZOLE or any other medicines, please tell your doctor. If you are pregnant or a nursing mother, it is advised to consult a doctor before using FLUCONAZOLE+ORNIDAZOLE. Drive only if you are alert as FLUCONAZOLE+ORNIDAZOLE may cause drowsiness, dizziness, or light-headedness. Avoid alcohol consumption with FLUCONAZOLE+ORNIDAZOLE as it may cause adverse effects such as nausea, increased heartbeat, chest pain, thirst, flushing (reddening of the skin), or low blood pressure. You are recommended to complete the full course of FLUCONAZOLE+ORNIDAZOLE as prescribed by your doctor for effective results. If you have adrenal insufficiency (adrenal glands do not produce sufficient amounts of steroid hormones), abnormal levels of calcium, magnesium, or potassium, kidney, liver, or heart problems inform your doctor before taking FLUCONAZOLE+ORNIDAZOLE. Avoid taking FLUCONAZOLE+ORNIDAZOLE with erythromycin, pimozide, cisapride, quinidine, terfenadine, and astemizole as it may cause adverse effects.

Drug Interactions

Drug-Drug Interaction: FLUCONAZOLE+ORNIDAZOLE may interact with a blood thinner (warfarin), muscle relaxant (vecuronium bromide), antibiotics (rifampicin, erythromycin, rifabutin), antidepressants (nortriptyline, amitriptyline), antifungals (voriconazole, amphotericin B), benzodiazepines (triazolam, midazolam), anticonvulsants (phenytoin, carbamazepine), pain relievers (ibuprofen, lornoxicam, meloxicam, diclofenac, celecoxib, flurbiprofen, naproxen), antiallergic drugs (astemizole, terfenadine), antipsychotic drug (pimozide), drug for stomach upset (cisapride), medicines used to lower high blood pressure (verapamil, felodipine, losartan, nifedipine, isradipine, amlodipine), antiarrhythmic agent (quinidine), anticancer drug (ibrutinib, olaparib), antiasthma drug (theophylline), anti-HIV drugs (saquinavir, zidovudine), antidiabetics (glibenclamide, glipizide, chlorpropamide, tolbutamide).

Drug-Food Interaction: No interactions found.  

Drug-Disease Interaction: If you have adrenal insufficiency (adrenal glands do not produce sufficient amounts of steroid hormones), abnormal levels of calcium, magnesium or potassium, kidney, liver or heart problems inform your doctor before taking FLUCONAZOLE+ORNIDAZOLE.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • VECURONIUM
  • RIFAMPICIN
  • ERYTHROMYCIN
  • RIFABUTIN
  • NORTRIPTYLINE
  • AMITRIPTYLINE
  • VORICONAZOLE
  • AMPHOTERICIN B
  • TRIAZOLAM
  • MIDAZOLAM
  • PHENYTOIN
  • CARBAMAZEPINE
  • IBUPROFEN
  • LORNOXICAM
  • MELOXICAM
  • DICLOFENAC
  • CELECOXIB
  • FLURBIPROFEN
  • NAPROXEN
  • ASTEMIZOLE
  • TERFENADINE
  • PIMOZIDE
  • CISAPRIDE
  • VERAPAMIL
  • FELODIPINE
  • LOSARTAN
  • NIFEDIPINE
  • AMLODIPINE
  • QUINIDINE
  • THEOPHYLLINE
  • SAQUINAVIR
  • ZIDOVUDINE
  • GLIBENCLAMIDE
  • GLIPIZIDE
  • CHLORPROPAMIDE
  • TOLBUTAMIDE
  • ISRADIPINE
  • IBRUTINIB
  • OLAPARIB
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid alcohol consumption with FLUCONAZOLE+ORNIDAZOLE as it may cause adverse effects such as nausea, increased heartbeat, chest pain, thirst, flushing (reddening of the skin) or low blood pressure. Please consult a doctor before consuming alcohol while using FLUCONAZOLE+ORNIDAZOLE.

    • Safety Warning

      Pregnancy

      caution

      Please consult a doctor if you are pregnant or planning for pregnancy. FLUCONAZOLE+ORNIDAZOLE is given to pregnant women only if the doctor thinks benefits outweigh risks.

    • Safety Warning

      Breast Feeding

      caution

      It is unknown whether FLUCONAZOLE+ORNIDAZOLE is excreted in human milk. FLUCONAZOLE+ORNIDAZOLE is given to breastfeeding mothers if the doctor thinks benefits are greater than risks. Please consult a doctor if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      FLUCONAZOLE+ORNIDAZOLE may cause drowsiness, dizziness or light-headedness. Therefore, avoid driving if you experience any of these symptoms after taking FLUCONAZOLE+ORNIDAZOLE.

    • Safety Warning

      Liver

      caution

      Take FLUCONAZOLE+ORNIDAZOLE with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take FLUCONAZOLE+ORNIDAZOLE with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      FLUCONAZOLE+ORNIDAZOLE should be used with caution and in doses only as prescribed by a doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
    • In wet places such as changing rooms and gym showers, don’t walk barefoot. Wear flip-flops or sandals to prevent fungal infections.
    • Do not scratch the affected area of the skin as it can spread the infection to other body parts.
    • Avoid sharing towels, combs, bedsheets, shoes, or socks with others to prevent the spread of infection.
    • Wash your bed sheets and towels regularly.
    • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

    Special Advise

    • Please consult a doctor if the infection persists or worsens after using FLUCONAZOLE+ORNIDAZOLE for 1 week.
    • If you experience diarrhea during the use of FLUCONAZOLE+ORNIDAZOLE, drink lots of water and consult your doctor, do not use any anti-diarrheal medicine on your own.

    Patients Concern

    Disease/Condition Glossary

    Fungal infection: It is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may affect the skin and spread into bones, tissues, organs, or the whole body. It may be contagious (spread from one person to another). The symptoms of a fungal infection include skin rash, darkening of the skin, peeling, itching, deformed toenail, or vaginal discharge. Antifungal medicines are usually used to treat fungal infections.

    Bacterial infection: It is a condition in which harmful bacteria grow in the body and cause infection. It can target any part of the body and multiply very quickly. Bacteria come in three basic shapes, namely spherical, rod, or spiral-shaped. Bacteria may be gram-positive (have thick cell walls) or gram-negative (do not have cell walls). Appropriate tests are done to identify bacterial strains and based on the results, proper medication is prescribed. Some common symptoms of bacterial infection include cough, fever, and tiredness.

    FAQs

    How does FLUCONAZOLE+ORNIDAZOLE work?

    FLUCONAZOLE+ORNIDAZOLE contains Fluconazole and Ornidazole. Fluconazole is an antifungal that works by damaging the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Thereby, kills fungi. Ornidazole is an antiprotozoal that works by damaging the DNA (genetic material) of bacteria and protozoa and inhibits the formation of new DNA. Thereby, kills micro-organisms and clears the infection.

    Does FLUCONAZOLE+ORNIDAZOLE cause diarrhoea?

    FLUCONAZOLE+ORNIDAZOLE may cause diarrhoea as a temporary adverse effect. However, if the condition persists or worsens or if you notice blood in stools, please consult your doctor.

    Can I take FLUCONAZOLE+ORNIDAZOLE with erythromycin?

    You are not recommended to take FLUCONAZOLE+ORNIDAZOLE with erythromycin as co-administration of these medicines may increase the risk of abnormal heart rhythm. However, please consult your doctor before taking FLUCONAZOLE+ORNIDAZOLE with other medicines.

    Does FLUCONAZOLE+ORNIDAZOLE cause liver problems?

    FLUCONAZOLE+ORNIDAZOLE may cause liver problems in some people. It is not necessary for everyone taking FLUCONAZOLE+ORNIDAZOLE to experience liver problems. However, if you experience loss of appetite, vomiting, tiredness or yellowing of skin or eyes, please consult a doctor immediately as these might be signs of liver problems.

    Does fungal infections spread from person to person?

    Fungal infections are contagious, so they can pass from one site of the body to the other. They can also pass from person to person through skin to skin contact, through clothes or through contact with contaminated surfaces and objects.

    Is FLUCONAZOLE+ORNIDAZOLE used to treat bacterial infections?

    FLUCONAZOLE+ORNIDAZOLE may be used to treat bacterial infections. FLUCONAZOLE+ORNIDAZOLE contains Ornidazole, an antiprotozoal drug that kills bacteria and protozoa.

    Available Medicines for

    FLUCONAZOLE+ORNIDAZOLE