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About GANIRELIX

GANIRELIX belongs to the group of medicines called antigonadotropin-releasing hormones used to treat infertility in women. It is indicated for the inhibition of premature luteinising hormone (LH) surges in women undergoing controlled ovarian hyperstimulation.

GANIRELIX contains Ganirelix, which works by inhibiting the action of gonadotropin-releasing hormone (GnRH), resulting in the suppression of the LH. It prevents women from ovulating too soon during the stimulation of their ovaries to produce a mature egg.

In some cases, GANIRELIX may cause side effects such as injection site reactions, nausea, and headache. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

Let the doctor know if you are allergic to any components in GANIRELIX. Do not use GANIRELIX if you are pregnant or breastfeeding. There is no relevant use of GANIRELIX in children. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of GANIRELIX

Female infertility

Medicinal Benefits

GANIRELIX belongs to the group of medicines called antigonadotropin-releasing hormones used to treat infertility in women. It is indicated for the inhibition of premature luteinising hormone (LH) surges in women undergoing controlled ovarian hyperstimulation. GANIRELIX contains Ganirelix, which works by inhibiting the action of gonadotropin-releasing hormone (GnRH), resulting in the suppression of the LH. It prevents women from ovulating (release of the egg from the ovary) too soon during the stimulation of their ovaries to produce a mature egg.

Directions for Use

Use GANIRELIX exactly as advised by the doctor. GANIRELIX should be administered subcutaneously (under the skin), like the stomach or thigh. Wash your hands thoroughly with soap and water. Swab the injection site with a disinfectant to remove any surface bacteria. Pinch a fold of skin with the index finger and thumb. Insert the needle at the base of the pinched-up skin at an angle of 45° to the skin surface. Once the needle has been correctly placed, push the plunger down slowly and steadily so the solution is correctly injected and the skin tissues are not damaged. Push the plunger down until the syringe is empty, and wait for 5 seconds. Vary the injection site with each injection.

Storage

Store in a cool and dry place away from sunlight

Side Effects of GANIRELIX

  • Nausea
  • Headache
  • Injection site reactions (redness, with or without swelling)

In-Depth Precautions and Warning

Drug Warnings

Do not use GANIRELIX if you are allergic to any of its components, if you are hypersensitive to gonadotropin-releasing hormone (GnRH) or a GnRH analogue, if you have a moderate or severe kidney or liver disease, or if you are pregnant or breastfeeding. During or following hormonal stimulation of the ovaries, ovarian hyperstimulation syndrome may develop. There may be a slightly increased risk of an ectopic pregnancy (pregnancy outside of the uterus) in women with damaged fallopian tubes. Inform the doctor if you weigh below 50 kg or above 90 kg. Let the doctor know if you are taking any other medicines, including vitamin/mineral supplements or herbal products.

Drug Interactions

Drug-Drug Interactions: No interactions found/established.

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: No interactions found/established.

Drug-Drug Interactions Checker List:

Safety Advice

  • Safety Warning

    Alcohol

    consult your doctor

    It is not known if alcohol affects GANIRELIX. Please consult your doctor.

  • Safety Warning

    Pregnancy

    unsafe

    Do not use GANIRELIX if you are pregnant, as it may cause birth defects.

  • Safety Warning

    Breast Feeding

    unsafe

    Do not use GANIRELIX if you are breastfeeding.

  • Safety Warning

    Driving

    consult your doctor

    The effect of GANIRELIX on the ability to drive has not been studied. Drive or operate machinery only if you are alert.

  • Safety Warning

    Liver

    caution

    GANIRELIX is not recommended for use if you have moderate or severe liver disease. Please consult the doctor if you have a liver impairment or any concerns regarding this.

  • Safety Warning

    Kidney

    caution

    GANIRELIX is not recommended for use if you have moderate or severe kidney disease. Please consult the doctor if you have kidney impairment or any concerns regarding this.

  • Safety Warning

    Children

    consult your doctor

    There is no relevant use of GANIRELIX in children or adolescents.

Habit Forming

No

Diet & Lifestyle Advise

  • Include healthy fruits and vegetables in your diet.
  • Avoid smoking and alcohol consumption.
  • Try relaxation therapy. Read a book or listen to soothing music.
  • Exercise moderately.
  • Do yoga or meditation, as it helps relieve stress.

Special Advise

  • You may need to have a negative pregnancy test before starting the treatment. 
  • Tell your doctor immediately if you become pregnant during therapy.

Patients Concern

Disease/Condition Glossary

Female infertility: It is a condition in which a woman cannot become pregnant even after trying for at least one year or six months if the woman is over 35 years old. Age, hormonal problems, physical problems, lifestyle or environmental factors could be the causes of infertility.

FAQs

How does GANIRELIX help?

GANIRELIX prevents women from ovulating too soon during the stimulation of their ovaries to produce a mature egg.

Can I stop using GANIRELIX on my own?

Do not stop using GANIRELIX unless advised by the doctor, as this may affect the outcome of your treatment. Talk to the doctor if you have any concerns.

Does GANIRELIX cause injection site reactions?

GANIRELIX may cause local injection site reactions like redness, with or without swelling. The local reaction usually disappears within 4 hours of administration. Vary the injection site with each injection.

Available Medicines for

GANIRELIX