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About GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE

GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE is a combination medicine used to treat bacterial eye and ear infections. It is used to treat eye infections such as conjunctivitis (infection of the outer white membrane of the eyeball), corneal ulcers (ulcer that occurs in the transplant membrane of the eye called the cornea), acute bacterial otitis media (an infection of the middle ear). Eye infections are contagious and can pass from one to another. 

GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE contains gentamicin, chlorpheniramine and zinc. Gentamicin inhibits the growth of bacteria by interfering with protein synthesis and leads to cell death. Chlorpheniramine maleate prevents the release of chemical messengers that cause red, itchy, and watery eyes. 

GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE may cause certain common side effects, such as (when used as eye drops) redness, itching, swelling, burning sensation, tearing, and temporary blurred vision (when used as ear drops), including ear pain and discomfort, discharge from ears, etc. If these side effects persist for an extended period of time, consult your doctor. Use GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE as prescribed by your doctor.

GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE should be avoided if you are allergic to it, other aminoglycoside antibiotics or any other ingredients present in it. Tell your doctor about all your current medications and medical history before using GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE. Inform your doctor if you have any vision or hearing problems after using this medication. Tell your doctor if you are pregnant or breastfeeding. 

Uses of GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE

Bacterial eye/ear infections

Medicinal Benefits

GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE is a combination medicine containing gentamicin, chlorpheniramine and zinc. Gentamicin inhibits the growth of bacteria by interfering with protein synthesis and leads to cell death. Chlorpheniramine maleate prevents the release of chemical messengers that cause red, itchy, and watery eyes. GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE is used to prevent and treat inflammation and prevent possible bacterial infection of the eye after cataract surgery in adults and children above two years of age. 

Directions for Use

Eye drops: Wash your hands thoroughly with water before and after use. Tilt your head and pull down the lower eyelid to create a small sac. Squeeze the prescribed amount of dose into the sac using the dropper. Close your eyes for about 2 to 3 minutes. Wipe any excess liquid with a tissue. Do not wipe or rinse the dropper tip after use. Place the dropper back on the bottle and tighten the cap. Ear drops: Wash your hands thoroughly with water before and after use. Tilt your head towards the side, take the prescribed dose with the dropper, and squeeze the drops in the ear.

Storage

Store in a cool and dry place away from sunlight

Side Effects of GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE

  • Eye redness

  • Burning sensation

  • Ear discomfort

  • Discharge from the ear

  • Ear pain

  • Dry eyes

  • Ringing sound 

In-Depth Precautions and Warning

Drug Warnings

It is for external use only. If you are allergic to GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE or any other medicines, please tell your doctor. Consult your doctor before using GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE if you are pregnant or breastfeeding. GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE is not recommended for children below 2 years of age. You are advised to remove soft contact lenses before using GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE as it contains a preservative that may cause eye irritation and discolouration of soft contact lenses. You can reinsert contact lenses after 15 minutes of using GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE. Do not use the topical non-steroidal inflammatory drug while using GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE. GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE contains dexamethasone; if you use a topical non-steroidal inflammatory drug and dexamethasone together, it may delay the healing of your eye wound. If you have diabetes, please consult your doctor before using GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE. The risk of intraocular pressure (glaucoma) and cataract formation is increased in diabetic patients. GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE may cause temporary vision problems (blurred vision), so be cautious while driving and operating machinery. 

Drug Interactions

Drug-drug interactions: GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE may interact with other antibiotics (e.g., vancomycin, kanamycin, streptomycin, cephalothin), pain relievers (e.g., diclofenac, bromfenac), antiviral (e.g., ritonavir, cobicistat, boceprevir, amprenavir, atazanavir), antifungal (e.g., itraconazole, ketoconazole), smallpox vaccine.

Drug-food interactions: No food interactions found.

Drug-disease interactions: GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE should be used with caution in patients with a corneal transplant, diabetes, myasthenia gravis, and Parkinson's disease.

Drug-Drug Interactions Checker List:

  • VANCOMYCIN
  • STREPTOMYCIN
  • DICLOFENAC
  • RITONAVIR
  • ITRACONAZOLE
  • Safety Advice

    • Safety Warning

      Alcohol

      consult your doctor

      The interaction of GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE with alcohol is unknown. Consult your doctor before consuming alcohol during the treatment with GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE.

    • Safety Warning

      Pregnancy

      caution

      If you are pregnant, consult your doctor before using GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE. It is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Consult your doctor before using GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE if you are breastfeeding. Your doctor will prescribe GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE only if the benefits outweigh the risks.

    • Safety Warning

      Driving

      unsafe

      GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE usually causes temporarily blurred vision and affects your driving ability when used in the eyes. Hence, avoid driving or operating machines until your vision is clear after using this medicine.

    • Safety Warning

      Liver

      consult your doctor

      GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE can be used in patients with liver disease if prescribed by a doctor.

    • Safety Warning

      Kidney

      consult your doctor

      GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE can be used in patients with kidney disease if prescribed by a doctor.

    • Safety Warning

      Children

      consult your doctor

      Please consult a doctor about using GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Sleep for at least 6-8 hours to rejuvenate your eyes naturally.

    • Wash your eyes with clean water at least 2-3 times a day

    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

    • Placing cooled tea bags on your eyes while they are closed can be a way to relax and unwind.

    • Avoid pricking your ears with cotton buds or fingers as it can scratch the skin and allow germs, which result in infection.

    • The ear infection can also occur due to improper cleaning of ears after bathing or swimming. Hence, cleaning your ears thoroughly with a clean and dry cloth is advised.

    Special Advise

    Do not take GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE without consulting a doctor, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections.

    Patients Concern

    Disease/Condition Glossary

    Bacterial eye infection: Bacterial eye infection occurs when pathogenic bacteria infiltrate any part of the eye, including the eyeball, conjunctiva, and cornea. Conjunctivitis, keratitis, and other bacterial eye infections are common. The inflammation or infection of the conjunctiva (white part of the eye) and the inner eyelid is known as conjunctivitis (pink eye). It is a highly contagious infection spread through eye secretions. Redness, itchiness, and discharge or crusting around the eye are all symptoms. Keratitis is an inflammation of the cornea caused by contact lens use, injury, diabetes, or surgery.

    Bacterial ear infection: Bacterial ear infection occurs when pathogenic bacteria infiltrate any part of the ear, including the eardrum, middle ear, and ear canal. Acute otitis media and otitis externa are two common bacterial ear infections. Acute bacterial otitis media is a middle ear infection that occurs behind the eardrum. It is most prevalent in children. Otitis externa (Swimmer's ear) is an infection of the ear canal, which connects to the eardrum. It is primarily caused by frequent pricking of the ear with cotton buds or inserting fingers into the ear, which results in ear infections.

    FAQs

    How does GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE work?

    GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE inhibits the growth of bacteria by interfering with protein synthesis and leads to cell death

    Can I take GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE without consulting a doctor?

    Do not use GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE without first consulting a doctor, as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections.

    What should I do if I forget or miss a dose?

    If you miss a dose of GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE, take it as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to compensate for a missed one.

    Available Medicines for

    GENTAMICIN+CHLORPHENIRAMINE MALEATE+ZINC SULPHATE