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About HAEMOCOAGULASE (BOTHROPS ATROX)

HAEMOCOAGULASE (BOTHROPS ATROX) belongs to the group of haemostatic agents used to prevent bleeding in conditions such as oral bleeding, pulmonary bleeding, traumatic bleeding, postoperative bleeding, and other external and internal haemorrhages. It is a snake-venom based enzymatic mixture.

HAEMOCOAGULASE (BOTHROPS ATROX) contains ''Haemocoagulase (Bothrops atrox)'' which is a haemostatic (meaning blood-stopping). It promotes blood clumping and coagulation and thereby effectively controlling bleeding.

HAEMOCOAGULASE (BOTHROPS ATROX) will be administered by a healthcare professional; do not self-administer. HAEMOCOAGULASE (BOTHROPS ATROX) may cause certain common side effects like pain, swelling, and redness at the site of injection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist.

If you are allergic to any of the constituents of HAEMOCOAGULASE (BOTHROPS ATROX), please inform the doctor. If you are pregnant or breastfeeding, please consult the doctor as HAEMOCOAGULASE (BOTHROPS ATROX) may not be recommended in these states. HAEMOCOAGULASE (BOTHROPS ATROX) should be used cautiously in the elderly or paediatric population. HAEMOCOAGULASE (BOTHROPS ATROX) should be used with caution in those suffering from chronic viral diseases such as HIV or hepatitis. 

Uses of HAEMOCOAGULASE (BOTHROPS ATROX)

Haemorrhage (bleeding)

Medicinal Benefits

HAEMOCOAGULASE (BOTHROPS ATROX) is used to treat bleeding in medical and surgical scenarios. Clinically, it is used to control bleeding in dental, gynaecological, oral and maxillofacial scenarios. It also finds use in the treatment of pulmonary haemorrhage. HAEMOCOAGULASE (BOTHROPS ATROX) contains Haemocoagulase (Bothrops atrox) which is a hemostatic (meaning blood-stopping) enzyme. It exerts thrombin and thromboplastin-like effect on the process of blood clotting, promoting blood clumping and coagulation. Thereby effectively controlling bleeding. The thrombin acts on serum fibrinogen and converts it into stronger fibrin chains which basically help tighten and retract clots, thereby arresting bleeding and promoting wound healing.

Directions for Use

HAEMOCOAGULASE (BOTHROPS ATROX) will be administered by a qualified healthcare professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of HAEMOCOAGULASE (BOTHROPS ATROX)

  • Pain
  • Swelling
  • Redness

In-Depth Precautions and Warning

Drug Warnings

Please inform the doctor of any known allergies or conditions you may suffer from, especially severe hypertension, thrombotic disease, DIC, Von Willebrand disease, haemophilia or any cardiac and vascular disorders. If you are pregnant or breastfeeding, please consult the doctor. Please consult your doctor if you have a clot-forming tendency. Do not use if HAEMOCOAGULASE (BOTHROPS ATROX) solution is coloured.

Drug Interactions

Drug-Drug Interactions: HAEMOCOAGULASE (BOTHROPS ATROX) may interact with blood-thinners (aspirin, warfarin, Coumadin), antihypertensive (reserpine), and steroid hormone (testosterone). Please consult your doctor before use.

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: HAEMOCOAGULASE (BOTHROPS ATROX) is contraindicated in case of hypersensitivity, thrombotic disorders, heart disease and hypercoagulability states. Please consult your doctor if you have a clot-forming tendency. 

Drug-Drug Interactions Checker List:

  • WARFARIN
  • COUMADIN
  • RESERPINE
  • TESTOSTERONE
  • ASPIRIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      It is not known whether it is safe to consume alcohol with HAEMOCOAGULASE (BOTHROPS ATROX). Please consult your doctor.

    • Safety Warning

      Pregnancy

      caution

      There is limited information on the effects of HAEMOCOAGULASE (BOTHROPS ATROX) on pregnancy. Please consult your doctor.

    • Safety Warning

      Breast Feeding

      caution

      There is limited information on the effects of HAEMOCOAGULASE (BOTHROPS ATROX) in nursing mothers. Please consult your doctor.

    • Safety Warning

      Driving

      caution

      There is limited information on the effects of HAEMOCOAGULASE (BOTHROPS ATROX) on driving abilities. Please consult your doctor.

    • Safety Warning

      Liver

      caution

      There is limited information on the effects of HAEMOCOAGULASE (BOTHROPS ATROX) on the liver. Please consult your doctor.

    • Safety Warning

      Kidney

      caution

      There is limited information on the effects of HAEMOCOAGULASE (BOTHROPS ATROX) on the kidney. Please consult your doctor.

    • Safety Warning

      Children

      caution

      HAEMOCOAGULASE (BOTHROPS ATROX) should be used with caution in children. Please consult your doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • In case of an allergic reaction post-injection, apply ice to the affected area.
    • Include healthy fruits and vegetables in your diet.
    • Avoid processed foods, excess salt and sugar.
    • Snack on nuts and seeds.
    • Avoid saturated foods.

    Special Advise

    • In case of an anaphylactic reaction, report to the doctor immediately.  Anaphylaxis is a reaction to the medicine, characterised by coughing, wheezing, nausea, vomiting, hives, rash, anxiety, confusion etc.

    Patients Concern

    Disease/Condition Glossary

    Haemorrhage: Severe bleeding and a drastic loss of blood from damaged blood vessels, is called a haemorrhage. Bleeding could occur due to trauma injury, medical conditions or due to the use of certain drugs. 

    FAQs

    How does HAEMOCOAGULASE (BOTHROPS ATROX) work?

    HAEMOCOAGULASE (BOTHROPS ATROX) contains ''Haemocoagulase (Bothrops atrox),'' which promotes the clotting process and arrests bleeding.

    How long does HAEMOCOAGULASE (BOTHROPS ATROX) take to work?

    If given as an intravenous injection, HAEMOCOAGULASE (BOTHROPS ATROX) takes 5 to 10minutes to start working and if given, intramuscularly or subcutaneously, it takes 20 to 30 minutes to work.

    Is it safe to take HAEMOCOAGULASE (BOTHROPS ATROX) with blood thinner medicines?

    Blood thinner medicines and HAEMOCOAGULASE (BOTHROPS ATROX) may have interaction. Inform your doctor if you are taking any blood thinner/anticoagulant medicines.

    Available Medicines for

    HAEMOCOAGULASE (BOTHROPS ATROX)