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About HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL

HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL is a vaccine used in the prevention of any invasive disease produced by Haemophilus influenzae and Tetanus. Haemophilus influenzae type B (Hib) can cause a variety of diseases ranging from pneumonia to meningitis (brain fever) in children under 5 years of age. Tetanus is a disease in which the causative bacteria produces painful muscle contractions, causing the muscles to become stiff and later lock, thereby restricting any free movement. 

HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL is composed of 'Haemophilus B conjugate, Sucrose, Tetanus toxoid and Thiomersal'. HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL functions by generating antibodies against the HiB polysaccharide, which the body recognises as a foreign substance and mounts an immune response against it. The tetanus toxoid portion bound to the HiB polysaccharide further augments immune activity by instigating a more long-term immunity mediated by immune cells called T-cells. Thus, HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL prevents diseases brought on by both HiB as well as tetanus.

HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL will be administered by a healthcare professional; do not self-administer. HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL may cause certain common side effects such as irritability, lethargy, redness and soreness at the site of injection. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects consistently.

Inform the doctor if your child has any known pre-existing allergy to any of the contents of HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL or has had a severe allergic reaction following a previous dose of HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL. Please inform the doctor of you/your child's detailed medical history, including any chronic disease, neurological disease, HIV or severe illness. Please also inform the doctor of you/your child’s vaccination history. Please consult your doctor before taking HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL if you are pregnant or breastfeeding.

Uses of HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL

Hib infections (Epiglottitis, Bronchitis, Pneumonia, Meningitis) and Tetanus 

Medicinal Benefits

HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL is a conjugate vaccine that contains 'Haemophilus B conjugate, Sucrose, Tetanus toxoid and Thiomersal'. It is used to prevent any invasive disease caused by Haemophilus influenzae type B and tetanus. Haemophilus B conjugate functions by generating antibodies against the HiB polysaccharide, which the body recognises as a foreign substance and mounts an immune response against. The tetanus toxoid portion bound to the HiB polysaccharide further augments immune activity by instigating a more long-term immunity mediated by immune cells called T-cells.

Directions for Use

HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL will be administered by a health care professional. Do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Side Effects of HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL

  • Soreness 
  • Tenderness 
  • Redness and flaring at the injection site

In-Depth Precautions and Warning

Drug Warnings

HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL is not meant to be used in those with a known hypersensitivity disorder and also in those who have had a severe allergic reaction called anaphylaxis (shortness of breath, wheezing, chest tightness, anxiety, confusion, fever are some symptoms) to a previous dose of HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL or any of its components. HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL should be used with caution in case of latex hypersensitivity. HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL should not be administered intravenously. HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL should be used with caution in case of those suffering from Guillain-Barre syndrome, a neurological disorder,  immunocompromised children or those suffering from HIV, cancers such as leukaemia, or agammaglobulinaemia. Please consult the doctor before using HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL during pregnancy or breastfeeding as the use of HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL is not routinely indicated in adults. It is advisable not to use HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL in conjunction with anticoagulant therapy and/or steroids and if prescribed, should be used with caution. Inform the doctor right away about any medications that your child is currently on and about any previous vaccination and medical history.

Drug Interactions

Drug-Drug Interaction: HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL may interact with immunosuppressants (cyclosporine, tacrolimus), and a drug used for multiple sclerosis (siponimod).

Drug-Food Interaction: No interactions found.

Drug-Disease Interaction: HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL should not be used in case of a previous severe allergic reaction to HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL or any of its components. HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL should be used with caution in patients suffering from a latex allergy. HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL may interact with disease conditions such as immunosuppression, leukaemia, other cancers or agammaglobulinemia. 

Drug-Drug Interactions Checker List:

  • CYCLOSPORIN
  • TACROLIMUS
  • SIPONIMOD
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      There is not enough literature to explain the effects of alcohol on HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL. Please consult your doctor before use.

    • Safety Warning

      Pregnancy

      caution

      There is not enough literature to explain the effects of HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL on pregnancy. Please consult your doctor.

    • Safety Warning

      Breast Feeding

      caution

      There is not enough literature to explain the effects of HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL on breastfeeding. Please consult your doctor in case of any concerns.

    • Safety Warning

      Driving

      caution

      There is not enough literature to explain the effects of HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL on driving. Do not drive if you experience any side effects that alter your thinking ability or concentration.

    • Safety Warning

      Liver

      caution

      If you/your child suffer from any known liver problems, please consult your doctor before use.

    • Safety Warning

      Kidney

      caution

      If you/your child suffer from any known kidney problems, please consult your doctor before use.

    • Safety Warning

      Children

      safe if prescribed

      HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL is routinely used in children below 5 years of age. However, it should not be used in case of neonates or infants younger than 6 weeks of age. Please consult your doctor if you have any concerns.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Apply an ice-pack on the injection site in case of pain or soreness.
    • It is important to keep your child hydrated post-vaccination. Make sure to give them plenty of water. 
    • In case of fever, consult your doctor before treating with any OTC medication.
    • Ensure a balanced diet for proper nourishment and immunity.
    • Keep your child's immunisations up to date.

    Patients Concern

    Disease/Condition Glossary

    Epiglottitis: The epiglottis is the flap-like structure that covers the larynx. Inflammation and infection of the epiglottis are called epiglottitis. It causes pain during swallowing, difficulty in breathing, shortness of breath, severe sore throat, fever, drooling, loss of appetite, cough and coryza.

    Bronchitis: The bronchi are the divisions of the trachea leading into the lungs. An increase in the normal diameter of the inner membrane lining the bronchi is called bronchitis. It leads to cough with sputum (wet cough), shortness of breath, wheezing, runny or blocked nose, nasal drip, headache, difficulty in sleeping, loss of concentration and/or sore throat.   

    Pneumonia: An inflammation and infection of the lungs, caused by a viral or bacterial infection, is called pneumonia. Symptoms include high fever, lethargy, confusion, dizziness, shortness of breath, cough, sickliness, nausea, cough with phlegm, difficulty in breathing, and loss of appetite. 

    Meningitis: The meninges are the covering layers of the brain and spinal cord. Inflammation of the meningeal layers is referred to as meningitis. It is also commonly called brain fever. It is characterised by symptoms such as fever, intolerance to lights, headache, nausea, vomiting, stiff neck and other neurological symptoms depending on the severity of the disease.

    Tetanus: It is a serious illness that is caused by the bacteria Clostridium tetani, which live in soil, saliva, dust, and manure. This infection can lead to painful muscle contractions, particularly jaw and neck muscles, arms, chest, abdomen, and leg. This further causes difficulty breathing and frequent spasms. 

    FAQs

    How does HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL work?

    HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL works by inducing antibody and cell-mediated immunity against tetanus and diseases caused by Haemophilus influenzae type B.

    Is HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL safe for use in children suffering from fits?

    It is best to consult your doctor before administering HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL. Any medical disorders or disturbances should be brought to the attention of your physician before the use of HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL.

    How to store HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL?

    HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL is to be stored in cold places at 2°C to 8°C. Do not freeze the vial.

    Does HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL cause redness at the injection site?

    HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL may cause redness at the site of injection. However, if the condition persists or worsens, consult a doctor.

    Available Medicines for

    HEMOPHILUS B CONJUGATE+SUCROSE+TETANUS TOXOID+THIOMERSAL