HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL belongs to a class of medication called 'anti-hypertensive' primarily used to treat hypertension (high blood pressure). Hypertension is a condition in which the force exerted by the blood against the artery walls becomes so high that it causes health problems, such as heart disease.
HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL is a combination of three drugs: Hydrochlorothiazide (diuretic), Losartan (angiotensin receptor blocker), and Ramipril (ACE inhibitors). Hydrochlorothiazide belongs to diuretics (water tablets) that increase the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Losartan helps in relaxing and widening blood vessels and helps in lowering blood pressure. This makes it easier for the heart to pump more amount of blood into the whole body. Ramipril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme that decreases angiotensin II production in the body causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Thus, together they lower high blood pressure.
Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience dizziness, weakness, blurred vision, nausea, headache, orthostatic hypotension (low blood pressure when standing up from sitting or lying position), high cholesterol or uric acid levels, electrolyte imbalance, diarrhea, chest pain, fast heartbeat, changes in taste or stomach pain. Most of these side effects of HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.
HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL is not recommended for pregnant women, especially in second and third trimesters, as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL. Avoid potassium supplements with HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL as it may lead to high potassium levels in the blood. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL.
Hypertension (high blood pressure)
HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL is a combination of three drugs: Hydrochlorothiazide (diuretic), Losartan (angiotensin receptor blocker), and Ramipril (ACE inhibitors). Hydrochlorothiazide belongs to diuretics (water tablets) that increase the removal of excess water and certain salts such as sodium and potassium from the blood. This removal of water from blood reduces the fluid volume circulating through blood vessels. Losartan helps in relaxing and widening blood vessels and helps in lowering blood pressure. This makes it easier for the heart to pump more amount of blood into the whole body. Ramipril belongs to the class angiotensin-converting enzyme (ACE) inhibitors that work by blocking an angiotensin-converting enzyme that decreases angiotensin II production in the body causes constriction and narrowing of blood vessels leading to high blood pressure. Thereby, it widens and relaxes blood vessels. Thus, together they lower high blood pressure.
If you are known to be allergic to HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL or any other medicines, please tell your doctor. HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL is not recommended for pregnant women, especially in second and third trimesters, as it may cause serious harm to the baby. Therefore, pregnant or breastfeeding women are advised to consult a doctor before taking HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL. It is advised to complete the full course of medication and does not suddenly stop taking HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL as it may cause recurring symptoms or worsen the condition. Avoid potassium supplements with HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL as it may lead to high potassium levels in the blood. If you are about to under any surgery, receive anesthetics, LDL apheresis treatment (cholesterol removal from blood using a machine), or desensitization treatment, inform your doctor that you are taking HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL. If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL.
Drug-Drug Interaction: HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL may have interaction with pain killers (aspirin), antidepressants (duloxetine, fluoxetine, sertraline), water tablets ( furosemide), anticonvulsants (pregabalin), medicines used to lower high blood pressure (metoprolol, amlodipine), bronchodilators (albuterol, salmeterol), vitamin (cholecalciferol).
Drug- Food Interaction: HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL may interact with potassium salt substitutes and potassium supplements, resulting in hyperkalemia (high levels of potassium in the blood) and may cause severe adverse effects such as irregular heartbeat, muscle paralysis, and kidney failure. Also, avoid intake of potassium-rich foods such as coconut water, bananas, and broccoli.
Drug-Disease Interaction: If you have asthma, diabetes, low blood pressure, difficulty in urination, gout, blood disorders, systemic lupus erythematosus (an autoimmune disease), scleroderma (hardening and tightening of skin), cerebrovascular disease (a condition affecting blood flow to the brain), have a history of angioedema (swelling under the skin) or skin cancer, kidney, liver or heart problems inform your doctor before taking HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL.
Avoid alcohol consumption with HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL as it may increase the risk of low blood pressure and cause adverse effects such as dizziness, fainting, light-headedness or headache.
Please consult a doctor if you are pregnant. HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL is not recommended for pregnant women, especially in the second and third trimesters as it may cause birth defects or serious harm to the baby.
HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL may be excreted in human milk. Therefore, HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL is not recommended for breastfeeding mothers as it may be unsafe for the baby. However, please consult a doctor.
HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL may cause dizziness or tiredness in some people. Therefore, avoid driving if you feel dizzy or tired after taking HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL.
HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL should be given with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL if you have severe liver problems.
HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL should be given with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required. Avoid taking HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL if you have severe kidney problems.
It is not recommended for children as the safety and effectiveness were not established.
Hypertension: Blood pressure is the measurement of the heart's force to pump blood to all parts of the body. Hypertension is a chronic condition in which blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Raised blood pressure can cause chest pain (angina) and heart attack (when blood supply to the heart is blocked). Additionally, high blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg and, diastolic pressure is 90 mm of Hg. Normal blood pressure lies in between 90/60 mm of Hg and 120/80 mm of Hg. If the blood pressure is 140/90 mmHg or greater, it is considered high blood pressure.
HYDROCHLOROTHIAZIDE+LOSARTAN+RAMIPRIL
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