About LENOGRASTIM
LENOGRASTIM belongs to the class of medicine called cytokines (immunostimulants). It is used to prevent infections after chemotherapy if the level of your white blood cells is too low (neutropenia), after a bone marrow or blood stem cell transplant or when you want to donate your blood stem cells. Neutropenia is a condition in which the quantity of neutrophils (white blood cells) in the blood is reduced.
LENOGRASTIM contains Lenograstim, which helps produce more white blood cells called neutrophils. Neutrophils are important in fighting infections.
A healthcare professional will administer LENOGRASTIM. Sometimes, you may experience injection site responses such as pain, redness, or swelling. You may also experience headache, fever, sickness (nausea), tiredness, decrease in platelets count, bleeding or bruising more easily than normal, injection site reaction, general aches and abdominal pain. Most of these side effects do not necessitate medical treatment and will gradually fade over time. However, if you suffer these side effects regularly, you should consult your doctor.
LENOGRASTIM is not recommended if you are allergic to lenograstim or any of the other ingredients of this medicine, have a type of cancer called ‘myeloid cancer’ or have cancer chemotherapy on the same day. However, you can have LENOGRASTIM if you have newly diagnosed ‘acute myeloid leukaemia’ in certain cases if you are more than 55 years old. Let your doctor know about all your medical conditions, sensitivities, and all medications you are using. LENOGRASTIM has not been tested in pregnant or breastfeeding women. So, inform your doctor if you are pregnant or breastfeeding, suspect you are pregnant, or plan to have a kid. LENOGRASTIM is not recommended for children under the age of two years.
Uses of LENOGRASTIM
Prevention of infections after chemotherapy, Neutropenia, after a bone marrow or blood stem cell transplant, and stem cell donation.
Medicinal Benefits
LENOGRASTIM contains Lenograstim. It acts by encouraging the bone marrow to generate more white blood cells, aiding infection resistance. LENOGRASTIM is used to boost white blood cell count following cancer treatment or chemotherapy, bone marrow transplantation, neutropenia, and when you want to donate your blood stem cells. It can also be used when the person needs to increase blood stem cells (mobilisation).
Directions for Use
Storage
Side Effects of LENOGRASTIM
- Headache
- Fever
- Feel sick (nausea)
- Feel tired
- Decrease in platelet count
- Bleed or bruise more easily than normal
- Injection site reaction
- General aches and pains
- Abdominal pain
In-Depth Precautions and Warning
Drug Warnings
If you are receiving anti-cancer chemotherapy, do not use LENOGRASTIM for 24 hours before the therapy begins and for 24 hours after the therapy concludes. If you want to donate your blood stem cells but are using an anti-coagulant (such as warfarin or heparin), inform your doctor before beginning the LENOGRASTIM therapy. Inform them if you are aware of any other blood clotting issues. Also, inform your doctor if you have ever had any illness, especially allergies, infections, kidney or liver problems, sickle cell disease or sickle cell trait. If you or your kid have a type of cancer called 'acute lymphocytic leukaemia' and are under the age of 18, inform your doctor before taking this medication.
Drug Interactions
Drug-Drug Interactions: LENOGRASTIM may have interaction with anti-cancer medications (e.g. Cyclophosphamide, Topotecan) and anti-coagulant treatment (e.g. Warfarin, Heparin).
Drug-Food Interactions: Limit or quit the consumption of alcohol.
Drug-Disease Interactions: LENOGRASTIM may cause interactions with disease conditions such as sickle cell disease or sickle cell trait, myeloid cancer, spleen illness, and Signs of allergic reactions.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is unknown whether consuming alcohol with LENOGRASTIM is safe. However, as a precaution, it is best to avoid or limit alcohol consumption.
Pregnancy
cautionThere are no adequate and well-controlled studies on pregnant women. Your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionIt is unknown whether LENOGRASTIM is excreted in human milk. Consult the doctor if you are breastfeeding. A decision should be made whether to discontinue nursing or to discontinue the medicine, taking into account the importance of the medicine to the mother.
Driving
cautionIt is not known whether LENOGRASTIM alters the ability to drive, so do not drive or operate machinery if you experience any symptoms that affect your ability to concentrate and react.
Liver
cautionInform your doctor before receiving the LENOGRASTIM if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionCaution should be exercised while using LENOGRASTIM in patients with kidney dysfunction. Monitoring of patients with kidney dysfunction is recommended. If you observe puffiness in your face or ankles, blood in your urine or brown-coloured urine, or if you urinate less than normal, consult your doctor immediately.
Children
cautionLENOGRASTIM is not recommended for children younger than two years.
Habit Forming
Diet & Lifestyle Advise
- De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
- Performing yoga may also help in improving both physical and mental health.
- Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
- Eat a healthy diet and exercise regularly to maintain proper weight.
- Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs.
- Get optimal sleep; rest well.
- Avoid smoking and alcohol consumption.
- Avoid fast, fried, processed meats, refined carbs and added sugars.
Special Advise
- LENOGRASTIM should be taken under strict medical supervision.
- Keep all appointments with your doctor and the laboratory. The doctor will regularly monitor your condition while taking LENOGRASTIM.
Patients Concern
Disease/Condition Glossary
Neutropenia: Neutropenia is characterized as a lower than the normal number of neutrophils (a type of white blood cell). White blood cells protect the body from infections. Without enough neutrophils, the body cannot fight bacteria, increasing the risk of many illnesses. Neutropenia can be caused by various conditions, including cancers like leukaemia, cancer treatment like radiotherapy, and infections like HIV or hepatitis.