About METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID
METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID is a combination medicine used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Liver diseases lead to disturbance of vital liver functions. METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID effectively prevents multiple liver disease mechanisms and ensures the liver's protection, regeneration, and rejuvenation.
METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID contains Metadoxine, Silymarin, L-ornithine-L-aspartate, Folic acid, and Pyridoxine hydrochloride. Metadoxine restores the liver's balance of saturated and unsaturated fatty acids by increasing the desaturase enzyme. It accelerates the metabolism of the liver, restores ATP synthesis and redox balance of hepatocytes. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps in the production of new liver cells. L-ornithine-L-aspartate rejuvenates the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine hydrochloride helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID helps in treating liver disease.
You can take METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID with or without food. Swallow METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID as a whole with water; do not crush or chew the tablet. You are advised to take METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID for as long as your doctor has prescribed it for you, depending on your medical condition. Sometimes, you may experience common side effects such as headache, fatigue, diarrhoea, abdominal pain, and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Let your doctor know if you are allergic to any of the contents. Consult your doctor before taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID if you are pregnant or breastfeeding. Be cautious while driving and operating machinery as it is unknown if METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID interferes with your ability to drive. Avoid consuming alcohol along with METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID as it could lead to further liver damage. METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID should not be given to children unless prescribed by the doctor.
Uses of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID
Liver disease
Medicinal Benefits
METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID is a combination of five drugs: Metadoxine, Silymarin, L-ornithine-L-aspartate, Folic acid, and Pyridoxine hydrochloride. METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID is used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Metadoxine restores the liver's balance of saturated and unsaturated fatty acids by increasing the desaturase enzyme. It accelerates the metabolism of the liver and the redox balance of hepatocytes. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps in the production of new liver cells. L-ornithine and L-aspartate rejuvenate the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine hydrochloride helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID helps in treating liver disease. A single drug does not prevent multiple mechanisms; hence, METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID effectively prevents multiple liver disease mechanisms and ensures the liver's protection, regeneration, and rejuvenation.
Directions for Use
Storage
Side Effects of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID
- Headache
- Fatigue
- Nausea
- Diarrhoea
- Abdominal pain
In-Depth Precautions and Warning
Drug Warnings
Do not take METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID if you are allergic to any content of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID. Consult your doctor before taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID if you are pregnant or breastfeeding. Avoid consuming alcohol, as it could lead to further liver damage. METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID should not be given to children unless prescribed by the doctor. Inform your doctor regarding your health condition and the medicines you are taking to rule out any side effects/interactions.
Drug Interactions
Drug-Drug Interactions: METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID may have interaction with an anti-Parkinson agent (levodopa).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interaction: No interactions found/established.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol as it may lead to further liver damage.
Pregnancy
cautionLimited information is available regarding the usage of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID in pregnancy. Let your doctor know if you are pregnant before taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID. your doctor will prescribe only if the benefits outweigh the risks.
Breast Feeding
cautionLimited information is available regarding the usage of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID in breastfeeding mothers. Consult your doctor before taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID; your doctor will decide whether METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID can be taken by breastfeeding mothers.
Driving
cautionIt is not known if METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID interferes with your ability to drive. Do not drive or operate machines if you experience any symptoms that affect your alertness.
Liver
safe if prescribedMETADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID is used to treat various liver conditions. So, it is probably safe to be taken by patients with liver impairment. If you have any concerns, discuss them with your doctor.
Kidney
cautionMETADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID is generally safe to be used in patients with kidney disease. However, please consult your doctor if you have any concerns.
Children
cautionLimited information is available regarding the usage of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE HYDROCHLORIDE+FOLIC ACID in children. Please consult your doctor.
Habit Forming
Diet & Lifestyle Advise
- Avoid alcohol consumption and quit smoking.
- Maintain a healthy weight by exercising regularly.
- Adopt a liver-friendly diet such as fibre-rich food.
- Cut down on fats, sugar, and salt.
- Avoid stress by practising yoga or meditation.
- Exercise regularly as it helps in reducing the accumulation of fat.
Patients Concern
Disease/Condition Glossary
Liver disease: The liver is an important organ responsible for carrying out many vital functions such as metabolism, detoxification of waste, and energy storage. Liver diseases occur due to disturbances in liver functions. Liver diseases include acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Hepatitis occurs due to viral infection leading to liver damage and inflammation, making it difficult for the liver to function properly. The fatty liver could occur due to excess alcohol consumption (alcoholic fatty liver) or other factors (non-alcoholic fatty liver). Liver cirrhosis is damage to the liver, which causes scarring and liver failure. Jaundice occurs due to the build-up of bilirubin in the blood, which causes the yellow discolouration of the skin and eyes. Symptoms include dark urine, yellowing skin and eyes, loss of appetite, fatigue, bloody or dark stools, nausea, and vomiting.
