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About METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID

METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID is a combination medicine used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Liver diseases lead to disturbance of vital liver functions. METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID effectively prevents multiple liver disease mechanisms and ensures protection, regeneration, and rejuvenation of the liver. 

METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID contains Metadoxine, Silymarin, L-ornithine-L-aspartate, Folic acid, and Pyridoxine. Metadoxine restores the balance of saturated and unsaturated fatty acids in the liver by increasing the desaturase enzyme. It accelerates the metabolism of the liver, restores ATP synthesis and redox balance of hepatocytes. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps in the production of new liver cells. L-ornithine-L-aspartate rejuvenates the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID helps in treating liver disease.

You are advised to take METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as headache, fatigue, diarrhoea, abdominal pain, and nausea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.

Let your doctor know if you are allergic to any of the contents. Consult your doctor before taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID if you are pregnant or breastfeeding. Avoid consuming alcohol with METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID as it could lead to further liver damage. METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID should not be given to children unless prescribed by the doctor. Keep your doctor informed if you are taking any other prescription/non-prescription medications, including herbal products and supplements.

Uses of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID

Liver disease 

Medicinal Benefits

METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID is a combination of five drugs: Metadoxine, Silymarin, L-ornithine-L-aspartate, Folic acid, and Pyridoxine. METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID is used to treat liver diseases such as acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Metadoxine restores the balance of saturated and unsaturated fatty acids in the liver by increasing the desaturase enzyme. It accelerates the metabolism of the liver and the redox balance of hepatocytes. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps produce new liver cells. L-ornithine and L-aspartate rejuvenate the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID helps in treating liver disease. A single drug does not prevent multiple mechanisms involved; hence, METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID effectively prevents multiple liver disease mechanisms and ensures protection, regeneration, and rejuvenation of the liver. 

Directions for Use

Swallow METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID a whole with a glass of water; do not chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID

  • Headache
  • Fatigue
  • Nausea
  • Diarrhoea
  • Abdominal pain

In-Depth Precautions and Warning

Drug Warnings

Do not take METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID if you are allergic to any of its components. Consult your doctor before taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID if you are pregnant or breastfeeding. Avoid consuming alcohol as it could lead to further liver damage. METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID should not be given to children unless prescribed by the doctor. Inform your doctor regarding your health condition and the medicines you are taking to rule out any side-effects/interactions.  

Drug Interactions

Drug-Drug Interactions: METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID may interact with an anti-Parkinson agent (levodopa).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: No interactions found/established.

Drug-Drug Interactions Checker List:

  • LEVODOPA
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      Avoid consumption of alcohol as it may lead to further liver damage.

    • Safety Warning

      Pregnancy

      caution

      Limited information is available regarding the usage of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID in pregnancy. Consult your doctor before taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID if you are pregnant or if you have any concerns regarding this; your doctor will prescribe only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      Limited information is available regarding the usage of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID in breastfeeding mothers. Consult your doctor before taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID; your doctor will decide whether METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID can be taken by breastfeeding mothers or not.

    • Safety Warning

      Driving

      caution

      It is not known if METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID interferes with your ability to drive. Be cautious while driving or operating machinery.

    • Safety Warning

      Liver

      safe if prescribed

      METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID is used to treat various liver diseases. So, it is probably safe to be taken by patients with liver impairment. However, consult your doctor if you have any concerns.

    • Safety Warning

      Kidney

      caution

      Please consult your doctor if you have any concerns regarding the usage of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID in patients with kidney impairment.

    • Safety Warning

      Children

      caution

      Limited information is available regarding the usage of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID in children. Please consult your doctor.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Avoid alcohol consumption and quit smoking. 
    • Maintain a healthy weight by exercising regularly.
    • Adopt a liver-friendly diet such as fibre-rich food.
    • Cut down on fats, sugar, and salt.
    • Avoid stress by practising yoga or meditation. 
    • Exercise regularly as it helps in reducing the accumulation of fat.

    Special Advise

    During the treatment with METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID, try to have a monthly liver function test (LFT). 

    Patients Concern

    Disease/Condition Glossary

    Liver disease: The liver is an important organ responsible for carrying out many vital functions such as metabolism, detoxification of waste, and energy storage. Liver diseases occur due to disturbance of liver functions. Liver diseases include acute and chronic hepatitis, chronic alcoholic liver damage, fatty liver, jaundice, liver cirrhosis, and non-alcoholic steatohepatitis (non-alcoholic fatty liver disease). Hepatitis occurs due to viral infection leading to liver damage and inflammation, making it difficult for the liver to function properly. The fatty liver could occur due to excess alcohol consumption (alcoholic fatty liver) or other factors (non-alcoholic fatty liver). Liver cirrhosis is damage to the liver, which causes scarring and liver failure. Jaundice occurs due to the build-up of bilirubin in the blood, which causes the yellowing of skin and eyes. Symptoms include dark urine, yellowing of skin and eyes, loss of appetite, fatigue, bloody or dark stools, nausea, and vomiting. 

    FAQs

    How does METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID work?

    METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID contains Metadoxine, Silymarin, L-ornithine, L-aspartate, Folic acid, and Pyridoxine. Metadoxine restores the balance of saturated and unsaturated fatty acids in the liver by increasing the desaturase enzyme. Silymarin helps in protecting the liver from free radical damage and prevents hepatic lipid peroxidation. It increases glutathione and protein synthesis and helps in the production of new liver cells. L-ornithine-L-aspartate rejuvenates the liver by increasing the rate of energy production in liver cells. It decreases ammonia levels in the blood by increasing ammonia detoxification. Pyridoxine helps in the metabolism of dietary carbohydrates and fats in the liver. Folic acid helps in correcting micronutrient deficiency. Together, METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID helps in treating liver disease.

    Can I stop taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID if I feel well?

    To treat your condition effectually, continue taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID.

    Can I take levodopa with METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID?

    Please consult your doctor before taking levodopa with METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID as it might lower the efficacy of levodopa.

    Does METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID cause diarrhoea?

    Diarrhoea could be a side-effect of METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID. Drink plenty of fluids and eat non-spicy food if you experience diarrhoea. Consult your doctor if you have severe diarrhoea or if you find blood in stools.

    How does METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID help the liver?

    METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID effectively prevents multiple liver disease mechanisms and ensures protection, regeneration, and rejuvenation of the liver. Thereby, treats liver disease and helps in the proper functioning of the liver.

    Available Medicines for

    METADOXINE+SILYMARIN+L ORNITHINE L ASPARTATE+PYRIDOXINE+FOLIC ACID