Empagliflozin+metformin
About Empagliflozin+metformin
Metformin+empagliflozin is used to treat Type 2 diabetes. Type 2 diabetes is a common condition that causes the level of glucose (sugar) in the blood to become too high. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups to lead a normal life.
Metformin+empagliflozin is composed of Empagliflozin and Metformin. This medicine works by blocking the sodium-glucose co-transporter-2 (SGLT-2) enzyme. This lowers renal reabsorption of glucose and increases urine excretion of glucose via inhibiting SGLT2.
In some cases, you may experience certain common side effects, such as frequent urination, mild skin rash or itchy skin, or diarrhoea, stomach ache, and loss of appetite. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Take this medication by mouth with or without food as directed by your doctor, usually once daily in the morning. The dosage is based on your medical condition and response to treatment. To help you remember, take it at the same time each day. Tell your doctor if your condition does not improve or worsens (if your blood sugar is too high or too low).
Do not consume Metformin+empagliflozin if you are allergic to any component present in Metformin+empagliflozin. If you are pregnant or breastfeeding, consult your doctor before taking Metformin+empagliflozin. Avoid drinking alcohol while taking Metformin+empagliflozin since it may produce unpleasant side effects. Inform your doctor about all of the medications you are taking, as well as your medical history, to rule out any undesirable side effects or interactions. Metformin+empagliflozin should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease.
Uses of Empagliflozin+metformin
Medicinal Benefits
- Metformin+empagliflozin is composed of two antidiabetic medicines:
- It reduces blood sugar levels in people with diabetes. It does this by helping remove excess sugar from your body through your pee.
- Metformin belongs to the class of biguanides and manages blood sugar levels, particularly in obese patients.
- It lowers your blood sugar levels by improving how your body handles insulin. Altogether, they lower blood glucose more effectively.
- Metformin+empagliflozin also helps to prevent serious complications of diabetes such as kidney damage (diabetic nephropathy), blindness (diabetic retinopathy), loss of sensation in your hands and feet (Diabetic Neuropathy) or even loss of a foot.
Directions for Use
- Metformin+empagliflozin should be taken with meals to prevent stomach upset.
- It is recommended to take Metformin+empagliflozin twice daily at the same time each day or as prescribed by your doctor.
- Swallow Metformin+empagliflozin as a whole with a glass of water.
- Do not crush, chew, or break it.
Storage
Side Effects of Empagliflozin+metformin
- Thrush
- Pain or a burning feeling when you pee
- Mild skin rash or itchy skin
- Feeling sick (nausea)
- Being sick (vomiting) or diarrhoea
- Stomach ache
- Loss of appetite
- A metallic taste in the mouth
- lactic acidosis
Medicines Containing this Salt
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Drug Warnings
- Before taking this medication, tell your doctor or pharmacist if you are allergic to empagliflozin and Metformin, or have other allergies.
- This product may contain inactive ingredients that can cause allergic reactions or other adverse effects.
- Metformin+empagliflozin should not be stopped even if you feel better, without consulting your doctor, as your sugar level keeps changing.
- If you stop taking Metformin+empagliflozin abruptly, it may increase your sugar levels, which could further increase the risk of eyesight loss (retinopathy), kidney (nephropathy), and nerve damage (neuropathy).
- Metformin+empagliflozin should not be taken if you have type 1 diabetes mellitus or severe kidney or liver disease.
- It's generally not recommended to take empagliflozin during pregnancy/breastfeeding. Discuss the risks and benefits with your doctor.
- Metformin+empagliflozin is only for adults (from 18 years). It is not recommended for anyone aged 85 years or older.
- It may be harder to control your blood sugar when your body is stressed (such as when you have a fever, infection, injury, or surgery).
- Also, if you eat less or cannot eat due to these conditions or any illness, this can lead to other side effects while taking this medication.
Drug Interactions
Drug-Drug Interactions: Metformin+empagliflozin may interact with Steroid tablets (e.g. prednisolone), diuretic medications (e.g. furosemide), chest pain medications (e.g. nitrates), muscle relaxants (baclofen), medicines that cause low blood sugar (e.g. insulin, gliclazide).
Drug-Food Interactions: Avoid alcohol intake since it increases the risk of lactic acidosis.
Drug-Disease Interactions: Metformin+empagliflozin is contraindicated in patients with uncontrolled diabetes, liver or kidney problems, severe infection, severe problems with circulation or breathing difficulties being treated for heart failure, or recently having a heart attack.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionIt is advised to avoid alcohol intake since it may worsen the side effects like lactic acidosis and increase the risk of developing low blood sugar levels.
Pregnancy
cautionEmpagliflozin in Metformin+empagliflozin is not generally recommended in pregnancy. It is not clear whether empagliflozin can harm an unborn baby. Your doctor may suggest other medications to control your blood sugar levels. Please consult your doctor before starting the Metformin+empagliflozin if you are pregnant or planning to conceive.
Breast Feeding
cautionMetformin+empagliflozin may be unsafe to use during breastfeeding since it is excreted into breast milk. Please seek medical advice for further information.
Driving
cautionYou’re driving may be affected if your blood sugar levels are too high or too low. Do not drive or operate machinery if you also experience blurred vision, dizziness or drowsiness due to extremely low or high blood sugar.
Liver
cautionInform your doctor before receiving Metformin+empagliflozin if you have a liver impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Kidney
cautionInform your doctor before receiving Metformin+empagliflozin if you have a kidney impairment/disorder history. Your doctor will prescribe only if the benefits outweigh the risks.
Children
unsafeMetformin+empagliflozin is not recommended for people younger than 18 years of age.
Habit Forming
Diet & Lifestyle Advise
- Take the medication as directed by the doctor and at regular intervals if you take Metformin+empagliflozin more than once per day. Do not use other over-the-counter medicines, herbal or vitamin supplements without informing your pharmacist or doctor when you take Metformin+empagliflozin.
- Maintain a fibre-rich diet and include healthy carbohydrates from fruits, vegetables and whole grains to maintain your blood glucose levels.
- Eat at regular intervals.
- Keep a check on your weight and exercise regularly to keep your heart healthy.
- Your doctor also guides you on noticing and managing the early symptoms of high/low blood sugar levels.
- Gastrointestinal side effects can be managed with simple modifications in your lifestyle. These include reducing sugars and fatty foods and avoiding carbonated drinks and foods that cause gas.
Special Advise
- It is advised to monitor your blood sugar levels regularly.
- If you need to undergo any x-ray or CT scan using a dye that should be injected into your veins, your doctor may suggest you stop taking Metformin+empagliflozin temporarily.
- Regular monitoring of kidney functioning is advised while using Metformin+empagliflozin.
- Metformin+empagliflozin may make you test positive for a urine glucose test. Hence inform your doctor in advance that you take Metformin+empagliflozin.
Patients Concern
Disease/Condition Glossary
Type 2 diabetes: Type 2 diabetes is a common condition that causes the level of glucose (sugar) in the blood to become too high. It can cause symptoms like excessive thirst, needing to pee a lot and tiredness. It can also increase your risk of getting serious problems with your eyes, heart and nerves. It's a lifelong condition that can affect your everyday life. You may need to change your diet, take medicines and have regular check-ups. It's caused by problems with a chemical in the body (hormone) called insulin. It's often linked to being overweight or inactive or having a family history of type 2 diabetes.
FAQs
Metformin+empagliflozin is used to treat Type 2 diabetes, a condition that causes the level of glucose (sugar) in the blood to become too high.
Metformin+empagliflozin is composed of two antidiabetic medicines: Empagliflozin and Metformin. Empagliflozin works by increasing the amount of sugar that leaves your body in your pee. Metformin lowers your blood sugar levels by improving how your body handles insulin. Altogether, they lower blood glucose more effectively.
Your doctor may advise Metformin+empagliflozin with or without other medications to control your blood sugar levels. However, it is advised to maintain a proper diet and exercise to control blood sugar levels while using Metformin+empagliflozin with or without other antidiabetic drugs.
It is not recommended to use Metformin+empagliflozin along with diuretics. Simultaneous use of Metformin+empagliflozin with diuretics can cause dehydration, and may these can increase your risk of dehydration and lower your blood pressure.
Diabetes is normally treated for the rest of one's life. Do not discontinue taking Metformin+empagliflozin pills without first consulting your doctor.
It is safe to take empagliflozin for a long time. There is no proof that this medication is harmful to your overall health.
Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.
There is no cure for diabetes. Metformin+empagliflozin only helps to control type 2 diabetes. However, it is advised to maintain proper diet and exercise along with Metformin+empagliflozin to control blood sugar levels.
You should take Metformin+empagliflozin with or without food or as prescribed by your doctor. Do not change the dose or prolong the duration of intake.
