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About METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE

METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE used to control nausea and vomiting during pregnancy. It helps treat morning sickness (nauseous feeling during the first trimester) in pregnant women. Nausea is an uneasy feeling in which a person feels an urge to vomit, while vomiting is the body's natural response to discharge the stomach content forcefully.

METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE contains Methylcobalamin, L Methylfolate Calcium, Pyridoxal 5 Phosphate (vitamin B6) and Doxylamine Succinate. Methylcobalamin and L Methylfolate Calcium can provide essential nutrients during pregnancy. Doxylamine succinate belongs to the class of antihistamines that work by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine/vitamin B6 deficiency may cause nausea and vomiting during pregnancy. Pyridoxal-5-phosphate works by increasing the level of vitamin B6 in the body. Thus, it helps treat nausea and vomiting during pregnancy.

Take METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE as prescribed. You are advised to take METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as drowsiness, constipation, dizziness, or blurred vision. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

If you are allergic to any foods or medicines, please tell your doctor. The METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE is usually not taken by breastfeeding mothers as it passes into breast milk. METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE should not be given to children as safety and efficacy have not been established. METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE may cause dizziness; therefore, drive with caution. Avoid consuming alcohol along with METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE as it could lead to increased dizziness. If you are taking MAO inhibitors, inform your doctor, as taking them along with METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE may cause unpleasant side effects.

Uses of METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE

Treatment of nausea and vomiting in pregnancy

Medicinal Benefits

METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE combines four drugs: Methylcobalamin, L-methyl folate calcium, pyridoxal 5 phosphate (vitamin B6), and doxylamine succinate. METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE relieves nausea and vomiting that occurs in pregnancy due to some hormonal changes. It acts by blocking the activity of some chemicals which make you sick. It will also increase your vitality during pregnancy.

Directions for Use

Swallow it as a whole with a glass of water; do not chew or crush it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE

  • Drowsiness
  • Dizziness
  • Blurred vision
  • Constipation

In-Depth Precautions and Warning

Drug Warnings

Do not take METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE if you are allergic to any of its contents. Tell your doctor if you have asthma, increased eye pressure, narrow-angle glaucoma, stomach ulcer, a blockage in your gut (digestive tract), or liver or kidney problems. Inform your doctor if you are taking medicines for depression, cough or cold medicines, sleeping medicines, or certain pain medicines. METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE should not be taken by breastfeeding mothers as it passes into breast milk. METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE as it could lead to increased dizziness.

Drug Interactions

Drug-Drug Interactions: METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE may interact with other antihistamine drugs (e.g. diphenhydramine, chlorpheniramine), anti-anxiety medications (e.g. alprazolam, chlordiazepoxide), monoamine oxidase inhibitors (e.g. selegiline, isocarboxazid), and sedative-hypnotics (lorazepam).
Drug-Food Interactions: You are recommended to avoid alcohol consumption while taking METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE since it could lead to increased dizziness and drowsiness.
Drug-Disease Interactions: METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE should be cautiously used in patients with depression, asthma/COPD, heart problems, severe liver or kidney diseases, glaucoma, and malabsorption syndrome.

Drug-Drug Interactions Checker List:

  • DIPHENHYDRAMINE
  • CHLORPHENIRAMINE
  • ALPRAZOLAM
  • CHLORDIAZEPOXIDE
  • SELEGILINE
  • ISOCARBOXAZID
  • LORAZEPAM
  • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are recommended to avoid alcohol consumption while taking METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE since it could lead to increased dizziness and drowsiness.

    • Safety Warning

      Pregnancy

      safe

      METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE is intended for use in pregnant women. However, please consult your doctor if you have any concerns.

    • Safety Warning

      Breast Feeding

      safe if prescribed

      Limited data is available. It is safe to take METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE in breastfeeding if prescribed by a doctor.

    • Safety Warning

      Driving

      caution

      METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE may cause dizziness, drowsiness, and blurred vision; hence, do not drive or operate heavy machinery if you feel dizzy.

    • Safety Warning

      Liver

      consult your doctor

      Limited information is available about using METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE in patients with liver disease. If you have liver problems, inform your doctor before taking METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE.

    • Safety Warning

      Kidney

      consult your doctor

      Limited information is available about using METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE in patients with kidney disease. If you have kidney problems, inform your doctor before taking METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE.

    • Safety Warning

      Children

      unsafe

      METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE is not recommended for children below 18 years of age, as the safety and efficacy have not been established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Limit taking foods and drinks that contain chocolate, alcohol, caffeine, fructose, or sorbitol, carbonated drinks, fried, and fatty foods. 
    • Do not have large meals at a time; instead, try having small and simpler meals at regular intervals, including fresh fruits and vegetables in your diet.
    • Practice yoga and recreation techniques to manage your emotional stress.
    • If you are lactose intolerant, avoid using dairy products since it can worsen your stomach discomfort.
    • If you cannot take dairy products, it is advised to include other calcium-rich foods like leafy greens, beans, nuts, and seeds.
    • Drink plenty of fluids to prevent dehydration.
    • Manage stress, eat healthily, drink plenty of water, exercise regularly, and get plenty of sleep.

    Patients Concern

    Disease/Condition Glossary

    Morning sickness: It is a common symptom during pregnancy that usually happens within the first trimester (first three months) of pregnancy, but some pregnant women have it throughout pregnancy. In some cases, pregnant women experience excessive nausea and vomiting that progresses to a condition called hyperemesis gravidarum. It causes electrolyte imbalance and weight loss in pregnant women. The most common cause of morning sickness is increased hormone levels during the first weeks of pregnancy.

     

    Nausea: It is an uneasy feeling in the stomach that may come and go in waves in which a person feels a strong urge to vomit. It happens before vomiting.

     

    Vomiting: It is a natural response of the body in which a person expels stomach contents from the mouth forcefully. It can be triggered by taste, anxiety, smell, pain or irritation to the stomach.

    FAQs

    How does METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE work?

    METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE contains methylcobalamin, L-methyl folate calcium, pyridoxal 5 phosphate (vitamin B6), and doxylamine succinate. Methylcobalamin and L Methylfolate Calcium can provide essential nutrients during pregnancy. Doxylamine succinate works by blocking the natural chemical (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxal-5-phosphate works by increasing the level of vitamin B6 in the body and treating nausea and vomiting during pregnancy.

    What if I overdose on METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE?

    Never increase your prescribed dose. If you have taken an overdose of this medicine accidentally, seek emergency medical help.

    Does METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE cause constipation?

    METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE may cause constipation as one of its side effects. You can avoid it by including high-fibre food in your diet that helps improve digestion. Limit the intake of alcohol to manage your constipation.

    What if I miss a dose of METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE?

    Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and return to your regular dosing schedule. Do not double the dose.

    Available Medicines for

    METHYLCOBALAMIN+L METHYLFOLATE CALCIUM+PYRIDOXAL 5 PHOSPHATE+DOXYLAMINE SUCCINATE