METOLAZONE is an antihypertensive drug that is used for the treatment of hypertension. METOLAZONE comes under the category of thiazide diuretic that prevents the body from absorbing an excessive amount of salt that may cause fluid retention. High blood pressure is known as hypertension. This is a medical condition in which the blood exerts high blood pressure against the walls of the blood vessel. Due to this, the heart has to work harder to pump the blood supply into the whole body. Hypertension can put a person on severe health complications, including stroke, heart failure, heart attack, and aneurysm.
Blood pressure is defined by the amount of blood pumped by the heart and the amount of resistance exerted by the arteries against the blood flow. During hypertension, arteries become narrower, and the heart starts pumping more blood resulting in high blood pressure. Uncontrolled blood pressure can put a person at risk of serious diseases.
The mechanism of METOLAZONE inhibits sodium's reabsorption in the body, resulting in an increase in chloride, sodium, and water excretion through urine. The shift in electrolytes and sodium levels reduces vascular resistance and makes the heart work normally. The production of diuresis and removal of excessive salt and fluid helps to lower blood pressure.
METOLAZONE is an oral medication that means to be taken by mouth. Follow the doctor's instructions carefully, and take METOLAZONE in the same way as directed by the doctor. Do not increase or reduce the dose; tell them about all the medicines and health problems. Do not change the dosage, stop, or start the METOLAZONE without checking with the doctor. METOLAZONE can make a person feel dizzy, so one should avoid doing activities like driving that need mental alertness. Along with the desired effects, METOLAZONE may cause some side effects, including headache, vomiting, itching, etc. Some of the side effects of METOLAZONE do not require medical attention and will pass with time. However, if a person is facing serious side effects or the side effects do not go away in a couple of days, then they must consult with their doctor about it.
Hypertension
METOLAZONE is prescribed for treating high blood pressure. Being a diuretic medication, METOLAZONE enhances the excretion of sodium and water through urine by restricting sodium absorption in the nephron tubes. If high blood pressure is not controlled for a longer time, then arteries and the heart will not be able to function properly. This may further increase the chances of damage of brain blood vessels, resulting in heart attack and serious kidney failure. However, taking METOLAZONE at the right time can control the blood pressure and make the heart function properly.
METOLAZONE can increase the chances of light-headedness, so rise slowly if you are sitting and avoid operating any machine or doing any work that needs mental alertness. Before taking METOLAZONE, tell the doctor if you have any allergies to the active and inactive ingredients present in it, kidney, liver, or heart disease. METOLAZONE may lower the potassium level in the body, so ask the doctor about how to add it to the diet. METOLAZONE should only be given during pregnancy when the doctor strongly suggests it. METOLAZONE could pass in the breast milk so ask your doctor before taking it if you are a breastfeeding woman.
Drug-Drug interactions: METOLAZONE may interact with different medicines. To prevent such interaction, one should tell their doctor about all the medications they are taking or if they have a previous drug history. Some drugs that can interact with METOLAZONE include other diuretic medications (furosemide, torsemide), other blood pressure drugs belonging to the category of angiotensin-converting enzyme (ACE) inhibitors (benazepril, perindopril, fosinopril, captopril), and Blood thinners (anticoagulants) including warfarin.
Drug-Food interactions: Recommended to limit the intake of salt.
Drug-Disease interactions: METOLAZONE can interact with certain diseases. Hence, it is advisable to tell the doctor about the past or current medical history, including anuria (kidneys aren't producing urine)/ renal dysfunction, fluid or electrolyte imbalance, liver disease, lupus erythematosus (an autoimmune inflammatory disease-causing scaly red patches on the skin), and asthma.
It is best to avoid or limit alcohol intake. Alcohol may aggravate the side effects and may cause a sudden drop in blood pressure and dizziness.
The use of METOLAZONE is not allowed during pregnancy until or unless prescribed by the doctor. METOLAZONE can only be used during the pregnancy if the benefits of METOLAZONE are more in comparison to the risks.
METOLAZONE tends to pass in the breast milk, so talk to your doctor before taking this medicine. A high dose of METOLAZONE may reduce the production of milk so never take it without consulting with a doctor.
METOLAZONE could make a person feel dizzy or drowsy. Therefore it is advised to avoid driving or doing any task that needs a clear vision.
METOLAZONE should be taken with caution as this is a diuretic medicine, so if a person is already dealing with liver disease, then METOLAZONE may cause serious loss of potassium from the body resulting in vomiting or diarrhoea.
METOLAZONE could cause a high level of nitrogen in the body. If a person is having trouble urinating, then the doctor will not allow the usage of METOLAZONE. However, the use of METOLAZONE is contraindicated in patients whose kidneys cannot produce urine.
METOLAZONE is not approved in children younger than 18 years of age.
Hypertension: Hypertension is a chronic medical condition when blood pressure is too high. Blood pressure is the measurement of the heart's force to pump blood to all body parts. When the heart pumps more blood, the arteries become narrower, and blood pressure becomes high. If the blood pressure becomes uncontrolled, it may cause serious heart diseases like brain damage (stroke), heart attacks, and kidney failure.