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About METOPROLOL SUCCINATE+AMLODIPINE

METOPROLOL SUCCINATE+AMLODIPINE belongs to the group of antihypertensive agents used to treat high blood pressure/hypertension and angina pectoris. High blood pressure is a condition in which the blood exerts increased pressure on the walls of blood vessels. Angina is basically a pain in the heart and chest. 

METOPROLOL SUCCINATE+AMLODIPINE contains Metoprolol succinate and Amlodipine. Metoprolol succinate works by slowing down the heart rate, thereby making it more efficient at pumping blood throughout the body. Amlodipine relaxes the blood vessels, thereby improving blood flow. Together, METOPROLOL SUCCINATE+AMLODIPINE helps treat high blood pressure.

Take METOPROLOL SUCCINATE+AMLODIPINE as prescribed. In some cases, METOPROLOL SUCCINATE+AMLODIPINE may cause certain common side effects such as tiredness, dizziness, headache, ankle swelling and slow heart rate. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if these side effects persist or worsen.

It is advisable to inform the doctor if you are allergic to any of its components. Consult your doctor if you are pregnant, planning to get pregnant, or breastfeeding. Keep your doctor informed in case you are due to undergo any surgery or dental procedure. Avoid consuming alcohol with METOPROLOL SUCCINATE+AMLODIPINE as there may be an interaction. METOPROLOL SUCCINATE+AMLODIPINE may cause dizziness, therefore, drive only if you are alert.

Uses of METOPROLOL SUCCINATE+AMLODIPINE

Hypertension, Angina pectoris

Medicinal Benefits

METOPROLOL SUCCINATE+AMLODIPINE is a combination antihypertensive medication containing Metoprolol succinate and Amlodipine. It is used primarily to treat hypertension and to relax the blood vessels for seamless flow of blood. Metoprolol succinate is a beta-blocker that eases the symptoms of hypertension by blocking catecholamines that lead to increased pressure and heart rate. Amlodipine is a calcium channel blocker that decreases blood pressure by preventing the influx of calcium ions into cells and by enlarging and relaxing arteries. In addition, METOPROLOL SUCCINATE+AMLODIPINE also reduces the oxygen demands of the heart, relaxing the heart and blood vessels and requiring the heart to do less work.

Directions for Use

Take METOPROLOL SUCCINATE+AMLODIPINE with or without food as directed by the physician. Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of METOPROLOL SUCCINATE+AMLODIPINE

  • Tiredness
  • Dizziness
  • Headache
  • Ankle swelling
  • Slow heart rate
  • Stomach pain
  • Shortness of breath
  • Rash or itch
  • Cold hands and feet

In-Depth Precautions and Warning

Drug Warnings

METOPROLOL SUCCINATE+AMLODIPINE should not be used in case of any known allergy to either of the components. METOPROLOL SUCCINATE+AMLODIPINE should be used with caution in case of high risk or previous history of any arterial or thrombotic disorders, shock, cardiovascular health disorders, diabetes, heart failure, or any disease-causing psoriasis. Please inform your doctor in case of any history of an overactive thyroid, asthma, phaeochromocytoma (high BP due to a tumour in the adrenal glands), myasthenia gravis (neuromuscular disorder), COPD, heart block, liver disease or renal disease. Consult your doctor before using METOPROLOL SUCCINATE+AMLODIPINE during pregnancy or breastfeeding. Keep your doctor informed in case you are waiting to undergo any surgery or dental procedure. METOPROLOL SUCCINATE+AMLODIPINE may interact with alcohol, please consult your doctor before use. METOPROLOL SUCCINATE+AMLODIPINE may cause dizziness, so drive or operate heavy machinery only if you are alert. 

Drug Interactions

Drug-Drug Interactions: METOPROLOL SUCCINATE+AMLODIPINE may interact with monoamine oxidase inhibitors, antiarrhythmic agents (quinidine, propafenone), anti-depressant (fluoxetine, paroxetine), anti-hypertensive (diltiazem, clonidine, verapamil), antibiotic (erythromycin), anti-fungal (ketoconazole, itraconazole), anti-viral (ritonavir), cardiac glycoside (digitalis), 

Drug-Food Interactions: METOPROLOL SUCCINATE+AMLODIPINE can interact with grapefruit juice, fish oil and castor oil.

Drug-Disease Interactions: METOPROLOL SUCCINATE+AMLODIPINE should be used with caution in patients with a known hypersensitivity disorder, shock, COPD, diabetes mellitus, heart failure, liver cirrhosis, myasthenia gravis, phaeochromocytoma, chronic diarrhoea, thromboembolic disorder, cardiovascular disorder and/or dry eyes.

Drug-Drug Interactions Checker List:

  • QUINIDINE
  • PROPAFENONE
  • FLUOXETINE
  • PAROXETINE
  • DILTIAZEM
  • CLONIDINE
  • VERAPAMIL
  • ERYTHROMYCIN
  • KETOCONAZOLE
  • ITRACONAZOLE
  • RITONAVIR
  • DIGITALIS

    • Safety Advice

    • Safety Warning

      Alcohol

      unsafe

      You are advised not to take alcohol with METOPROLOL SUCCINATE+AMLODIPINE as there may be an interaction, reducing the therapeutic effects of METOPROLOL SUCCINATE+AMLODIPINE. Please consult your doctor if you have any concerns.

    • Safety Warning

      Pregnancy

      caution

      METOPROLOL SUCCINATE+AMLODIPINE may be used in pregnancy only if absolutely warranted. Please consult your doctor if you have any concerns.

    • Safety Warning

      Breast Feeding

      caution

      METOPROLOL SUCCINATE+AMLODIPINE is not recommended for use during breastfeeding. Please consult your doctor if you have any concerns.

    • Safety Warning

      Driving

      caution

      METOPROLOL SUCCINATE+AMLODIPINE may cause dizziness or loss of alertness, which may affect your ability to drive.

    • Safety Warning

      Liver

      caution

      METOPROLOL SUCCINATE+AMLODIPINE is not recommended for use in those with established liver disease. Please consult your doctor in case of any concerns.

    • Safety Warning

      Kidney

      caution

      METOPROLOL SUCCINATE+AMLODIPINE is probably safe on the kidney but should be used with caution in those with renal impairment. Please consult your doctor in case of any concerns.

    • Safety Warning

      Children

      unsafe

      METOPROLOL SUCCINATE+AMLODIPINE is not recommended for use in children below 12 years of age. Please consult your physician if you have any concerns.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Limit the intake of salt in your diet.
    • Cut back on foods that are high in fat and cholesterol.
    • Eat more fruits, vegetables and whole-grain foods.
    • Avoid taking METOPROLOL SUCCINATE+AMLODIPINE with grapefruit juice as there may be an interaction.
    • Avoid tobacco use. Inform your doctor in case of marijuana use.
    • Dress warmly, as METOPROLOL SUCCINATE+AMLODIPINE may cause cold extremities.

    Special Advise

    • In case you miss a dose of METOPROLOL SUCCINATE+AMLODIPINE, take it as soon as possible. However, if it is too close to the next dose, revert to the original schedule. Do not ever take a double dose.
    • If you accidentally take an extra dose of METOPROLOL SUCCINATE+AMLODIPINE, please inform your doctor immediately. Some of the common symptoms of an overdose can be low blood pressure, slow pulse rate, shortness of breath, low blood sugar, dizziness, feeling sick and blue discolouration of the skin.
    • Do not discontinue taking METOPROLOL SUCCINATE+AMLODIPINE abruptly or without the advice of the physician.
    • Please know that your doctor may order blood tests to check your tolerance and need of METOPROLOL SUCCINATE+AMLODIPINE.
    • METOPROLOL SUCCINATE+AMLODIPINE should be used with caution in case of those over 80 or under 40 years of age.

    Patients Concern

    Disease/Condition Glossary

    Hypertension: Hypertension is defined as a condition in which the blood pressure remains high persistently. Normal BP is marked at 120/80 mmHg. Hypertension is defined as consistent blood pressure over 140/90 mm Hg. Hypertension expresses itself in various symptoms such as fatigue, irregular pulse rate, headache, dizziness, chest pain etc.

    Angina Pectoris: Discomfort in the chest or the heart is referred to as angina. It occurs when the workload on the heart increases and when the heart does not get as much blood as it needs. Symptoms of angina include chest tightness, pressure and heaviness in the chest.

    FAQs

    How does METOPROLOL SUCCINATE+AMLODIPINE work?

    METOPROLOL SUCCINATE+AMLODIPINE works by reducing the workload on the heart and vessels and relaxing the vessels to ensure a fluid flow of blood, easing any hypertension and effects of the same.

    Can I stop taking METOPROLOL SUCCINATE+AMLODIPINE on my own?

    Do not stop taking METOPROLOL SUCCINATE+AMLODIPINE without consulting your doctor as it may lead to a rise in blood pressure. To treat your condition effectually, continue taking METOPROLOL SUCCINATE+AMLODIPINE for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking METOPROLOL SUCCINATE+AMLODIPINE.

    I suffer from low blood sodium levels from time to time. Can I take METOPROLOL SUCCINATE+AMLODIPINE?

    Hyponatremia (a term for low blood sodium levels) often results in lowering blood pressure and falls. One of the not so common side-effects of METOPROLOL SUCCINATE+AMLODIPINE is dizziness and lowered BP. Hence, it is best to consult your physician before taking METOPROLOL SUCCINATE+AMLODIPINE if you suffer from this condition.

    Does METOPROLOL SUCCINATE+AMLODIPINE cause light-headedness?

    Light-headedness could be a side-effect of METOPROLOL SUCCINATE+AMLODIPINE. It occurs due to low blood pressure leading to dizziness on standing. If you experience this, do not try to stand up suddenly or start walking, instead lie down and get up slowly only when you feel better. People taking METOPROLOL SUCCINATE+AMLODIPINE are advised to regularly monitor their blood pressure levels to avoid unpleasant events.

    Can METOPROLOL SUCCINATE+AMLODIPINE affect my ability to get pregnant?

    METOPROLOL SUCCINATE+AMLODIPINE is not known to affect fertility. However, not enough literature and studies exist to ascertain the effect of METOPROLOL SUCCINATE+AMLODIPINE on fertility. Please consult your doctor in case of any concerns.

    Available Medicines for

    METOPROLOL SUCCINATE+AMLODIPINE