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About MOXONIDINE

MOXONIDINE belongs to the group of medicines called Antihypertensive used in the management of high blood pressure. High blood pressure is a medical condition in which the blood exerts high pressure against the walls of the arteries (blood vessels). This increases the heart's workload, and if it continues for a long time, the heart and arteries may not function properly. It can damage the kidney, brain and arteries of the heart. However, lowering blood pressure may reduce the risk of stroke and heart attacks.

MOXONIDINE contains 'Moxonidine', which relaxes and widens the blood vessels making it easier for the heart to pump blood to all body parts. This, in turn, helps decrease the raised blood pressure and the risk of having a heart attack or stroke in the future, especially for people with high blood pressure.

Your doctor will recommend how often you take MOXONIDINE based on your medical condition. Some people may experience dry mouth, dizziness, weakness (asthenia), rash or itching, insomnia (difficulty in sleeping), nausea, vomiting, and indigestion. Most of these side effects do not require medical attention and will resolve gradually over time. However, you should speak to your doctor if you experience these side effects.

Please tell your doctor if you are allergic to MOXONIDINE or any other medicines. If you are pregnant or breastfeeding, it is advised to inform your doctor before using MOXONIDINE.  Regular monitoring of blood pressure, electrolyte levels, and kidney functioning is advised while taking MOXONIDINE. You are advised to consume low salt and low-fat diet while taking MOXONIDINE. MOXONIDINE should not be given to children unless prescribed by the doctor. Avoid alcohol consumption while taking MOXONIDINE as it might increase certain side effects. Keep your doctor informed about all the medicines you are taking and your health condition to rule out any unpleasant side effects.

Uses of MOXONIDINE

Hypertension (high blood pressure)

Medicinal Benefits

MOXONIDINE belongs to the group of medicines called 'antihypertensive' used in the treatment of hypertension (high blood pressure). MOXONIDINE works by relaxing and widening the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in decreasing the blood pressure and the risk of having a heart attack or stroke and kidney problems in the future. MOXONIDINE needs to be taken regularly to be effective.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of MOXONIDINE

  • Dry mouth
  • Dizziness
  • Weakness (asthenia)
  • Rash or itching
  • Insomnia (difficulty in sleeping)
  • Nausea
  • Vomiting
  • Indigestion

In-Depth Precautions and Warning

Drug Warnings

Do not take MOXONIDINE if you are allergic to any of its ingredients. Inform your doctor if you have heart, liver, or kidney problems. Do not take MOXONIDINE with medicines that affect the heart rate like epinephrine, diltiazem, verapamil, and digoxin as it may cause arrhythmia (irregular heartbeat). Avoid taking MOXONIDINE if you are pregnant or breastfeeding. Do not consume alcohol while taking MOXONIDINE as it might cause unpleasant side effects. Inform your doctor about all the medicines you are taking and your health condition to rule out any unpleasant side effects. Regular monitoring of blood pressure, electrolyte levels, and kidney functioning is advised while taking MOXONIDINE. MOXONIDINE is not recommended in children below 18 years of age, as the safety and effectiveness were not established.

 

Drug Interactions

Drug-Drug Interactions: MOXONIDINE may interact with other antihypertensives (atenolol, metoprolol, propranolol), pain relievers (acetaminophen, tramadol), medicines used to treat bipolar disorder (aripiprazole and quetiapine), anti-anxiety (alprazolam, lorazepam, duloxetine), anti-epileptic (clonazepam, diazepam, pregabalin).

Drug-Food Interactions: Maintain low salt and low-fat diet while taking MOXONIDINE. Avoid alcohol consumption while taking MOXONIDINE as it might lower the blood pressure than normal.

Drug-Disease Interactions: MOXONIDINE may have interaction with depression, kidney dysfunction, heart problems such as bradyarrhythmia, and low blood pressure.

Drug-Drug Interactions Checker List:

  • ATENOLOL
  • METOPROLOL
  • PROPRANOLOL
  • ACETAMINOPHEN
  • TRAMADOL
  • QUETIAPINE
  • ALPRAZOLAM
  • LORAZEPAM
  • DULOXETINE
  • CLONAZEPAM
  • DIAZEPAM
  • PREGABALIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      You are recommended to avoid alcohol consumption while taking MOXONIDINE to avoid unpleasant side-effects.

    • Safety Warning

      Pregnancy

      caution

      It is not known if it is safe to take MOXONIDINE while you are pregnant. Please consult your doctor if you have any concerns regarding this; your doctor will prescribe you MOXONIDINE only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      It is not recommended to take MOXONIDINE while you are breastfeeding. Please consult your doctor if you have any concerns regarding this; your doctor will decide whether MOXONIDINE can be given to breast-feeding mothers or not.

    • Safety Warning

      Driving

      caution

      MOXONIDINE may impair your thinking and reactions, drive and operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. MOXONIDINE should be used with caution in patients with liver impairment/liver disease. Please consult your doctor if you have a liver impairment or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. MOXONIDINE should be used with caution in patients with kidney impairment/kidney disease. Please consult your doctor if you have kidney impairment or any concerns regarding this.

    • Safety Warning

      Children

      caution

      MOXONIDINE is not recommended for children below 18 years of age, as the safety and effectiveness were not established.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Include more whole grains, foods, vegetables, fruits, and low-fat dairy products in your diet.
    • Cut back the foods high in saturated fat, sugar, and cholesterol.
    • Follow your doctor's instructions as they will suggest you include regular exercise and a low sodium diet intake in your daily life.
    • Increase the intake of potassium-rich foods, including prunes, raisins, and orange juice in your diet, as it will help the body recover quickly.
    • Limit consumption of excess sodium and sugary drinks. For cutting back on sodium, start by reducing the sodium intake to 1500mg (about 2/3) teaspoon) and then gradually reduce it more.
    • Instead of munching chips or sweets, eat unsalted nuts and frozen yoghurt that is good for your health and keep the weight under control.
    • Check your weight at regular intervals to keep your eyes on weight fluctuation. Try to control your weight according to your BMI, so include exercising and healthy eating habits in your lifestyle.
    • Make a habit of regular exercising for at least 1-2 hours a day, or at least one should walk for about half an hour for good health. Doing this will lower the sugar level and maintain a normal heart rate.
    • Stress can worsen hypertension, so one should enjoy time with friends and include mindful activities in their daily routine.
    • Please keep a blood pressure record as it will help a person notice the fluctuations in their blood pressure.

    Patients Concern

    Disease/Condition Glossary

    Hypertension: Blood pressure is the measurement of the force that our heart uses to pump blood to all parts of the body. Hypertension is a chronic condition when blood pressure is too high. When the heart pumps more blood, the arteries become narrower, and in turn, blood pressure becomes high. However, if blood pressure becomes uncontrolled, then it may cause serious heart diseases like brain damage (stroke), heart attacks, and kidney failure. Blood pressure is indicated by systolic and diastolic. Systolic pressure represents the contraction and relaxation of the heart (the heart pumps out the blood). On the other hand, diastolic is the pressure in the vessel when the heart beats in a resting state. The normal blood pressure range is 120/80mmHg. Hypertension is detected when systolic blood pressure is more than 140mmHg, and diastolic pressure is higher than 90mmHg.

    FAQs

    How does MOXONIDINE work?

    MOXONIDINE belongs to the group of medicines called Antihypertensives that relaxes and widens the blood vessels making it easier for the heart to pump blood to all parts of the body. This helps in decreasing the blood pressure and the risk of having a heart attack or stroke.

    What are the common side effects of MOXONIDINE?

    Dry mouth, dizziness, weakness (asthenia), rash or itching, insomnia (difficulty in sleeping), nausea, vomiting, indigestion are some of the common side effects of MOXONIDINE.

    Can I stop taking MOXONIDINE on my own?

    Please do not stop taking MOXONIDINE without consulting your doctor on your own as it may lead to a rise in blood pressure. Continue taking MOXONIDINE for as long as your doctor has prescribed it to you. Do not be reluctant to speak with your doctor if you experience any difficulty while taking MOXONIDINE.

    Should I need to take MOXONIDINE even though the blood pressure became normal?

    Even if a person achieved their goal of bringing their blood pressure back to normal, they should not stop taking it without asking a doctor. Only after the doctor's recommendation, the dosage of MOXONIDINE could be adjusted.

    Can I need to continue MOXONIDINE for lifelong?

    As hypertension is a serious medical issue, so taking MOXONIDINE help to reduce the risk of heart disease and other serious conditions. So, one should not stop taking medicine without consulting with their doctor. However, depending upon the condition, the doctor will adjust the dosing.

    Available Medicines for

    MOXONIDINE