About OMEPRAZOLE+CINITAPRIDE
OMEPRAZOLE+CINITAPRIDE is used to treat gastroesophageal reflux disease (GERD), peptic ulcers and Zollinger-Ellison syndrome. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). Peptic ulcers are sores that develop on the inner lining of the intestine and stomach. Zollinger-Ellison syndrome is characterised by the formation of tumours in the upper part of the small intestine, which leads to excess acid production.
OMEPRAZOLE+CINITAPRIDE is a combination of two drugs: Omeprazole (proton pump inhibitor) and Cinitapride (gastroprokinetic agent). Omeprazole works by blocking the action of proton pumps that produce stomach acid. It reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. On the other hand, Cinitapride increases the movement of the food pipe (oesophagus), small intestine and stomach, thereby enhancing bowel movement and the digestive tract empties from the food in a shorter time. Together, OMEPRAZOLE+CINITAPRIDE helps prevent acid reflux, thereby relieving hyperacidity and heartburn.
Take OMEPRAZOLE+CINITAPRIDE as prescribed by your doctor. You are advised to take OMEPRAZOLE+CINITAPRIDE for as long as your doctor has prescribed it for you based on your medical condition. OMEPRAZOLE+CINITAPRIDE may cause side effects such as headache, diarrhoea, nausea, vomiting, flatulence (gas), stomach pain, or constipation. Most of these side effects of OMEPRAZOLE+CINITAPRIDE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
Please tell your doctor if you are allergic to Omeprazole, Cinitapride or any other medicines. If you are pregnant or breastfeeding, please inform your doctor before taking OMEPRAZOLE+CINITAPRIDE. Inform your doctor if you have reduced vitamin B12 as OMEPRAZOLE+CINITAPRIDE may reduce the absorption of vitamin B12. Tell your doctor if you have osteoporosis (weak and brittle bones). Drive only if you are alert, as OMEPRAZOLE+CINITAPRIDE may cause dizziness or vision disturbances in some people.
Medicinal Benefits
OMEPRAZOLE+CINITAPRIDE belongs to a class of medicines called gastrointestinal agents. It contains Omeprazole and Cinitapride, which are used to treat gastroesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. Omeprazole reduces the amount of acid the stomach produces and prevents excess acid from flowing back into the food pipe. Cinitapride increases the movement of the food pipe (oesophagus), small intestine, and stomach, thereby enhancing bowel movement and emptying the digestive tract in a shorter time. Together, OMEPRAZOLE+CINITAPRIDE helps prevent acid reflux, thereby relieving hyperacidity and heartburn.
Directions for Use
Storage
Side Effects of OMEPRAZOLE+CINITAPRIDE
- Headache
- Diarrhoea
- Nausea
- Vomiting
- Flatulence (gas)
- Stomach pain
- Constipation
In-Depth Precautions and Warning
Drug Warnings
Please tell your doctor if you are allergic to Omeprazole, Cinitapride or any other medicines. If you are pregnant or breastfeeding, please inform your doctor before taking OMEPRAZOLE+CINITAPRIDE. Inform your doctor if you have reduced vitamin B12 as OMEPRAZOLE+CINITAPRIDE may reduce the absorption of vitamin B12. If you get any skin rash, particularly in areas exposed to sun, or have joint pain, inform your doctor immediately. If you are taking OMEPRAZOLE+CINITAPRIDE for more than 1 year, it may increase the risk of fracture of the spine, hip, or wrist. Therefore, tell your doctor if you have osteoporosis (weak and brittle bones). Drive only if you are alert, as OMEPRAZOLE+CINITAPRIDE may cause dizziness or vision disturbances in some people. OMEPRAZOLE+CINITAPRIDE may decrease magnesium levels in the blood, especially if taken for more than 3 months. Therefore, regular blood tests are recommended to monitor magnesium levels.
Drug Interactions
Drug-Drug Interaction: If you are taking blood thinners (warfarin, clopidogrel), anticancer drugs (methotrexate), antipsychotics (phenothiazine), heart-related medicine (digoxin), opioid analgesics (morphine, fentanyl), anticholinergic drugs (atropine), anti-HIV drugs (atazanavir, saquinavir, nelfinavir), antifungals (ketoconazole, itraconazole), anticonvulsant (phenytoin) and antibiotics (clarithromycin, rifampicin), inform your doctor.
Drug-Food Interaction: OMEPRAZOLE+CINITAPRIDE may interact with St. John’s wort (herbal supplement used to treat depression).
Drug-Disease Interaction: If you have a blockage in your gut, bleeding, osteoporosis (weak and brittle bones), or liver or kidney problems, inform your doctor before taking OMEPRAZOLE+CINITAPRIDE.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
consult your doctorIf you have any concerns regarding alcohol consumption while using OMEPRAZOLE+CINITAPRIDE, please discuss them with your doctor.
Pregnancy
consult your doctorIf you are pregnant or planning for pregnancy, please inform your doctor before taking OMEPRAZOLE+CINITAPRIDE.
Breast Feeding
consult your doctorIf you are a breastfeeding mother, inform your doctor before taking OMEPRAZOLE+CINITAPRIDE.
Driving
cautionOMEPRAZOLE+CINITAPRIDE may cause dizziness or vision disturbances in some people. Therefore, drive only if you are alert after taking OMEPRAZOLE+CINITAPRIDE.
Liver
cautionYour doctor may adjust the dose if you have severe liver problems. Therefore, inform your doctor if you have any Liver problems.
Kidney
consult your doctorIf you have kidney problems, please inform your doctor before taking OMEPRAZOLE+CINITAPRIDE.
Children
consult your doctorPlease consult a doctor if you have any concerns regarding the use of OMEPRAZOLE+CINITAPRIDE for children.
Habit Forming
Diet & Lifestyle Advise
- Eat smaller meals more often.
- Maintain a healthy weight by regular exercising.
- Avoid lying down after eating as it causes acid reflux.
- Avoid tight-fitting clothes as it might increase the pressure on the abdomen, leading to acid reflux.
- Practice relaxation techniques and avoid stress by doing yoga or meditation.
- Avoid foods such as high-fat food, spicy food, chocolates, citrus fruits, pineapple, tomato, onion, garlic, tea, and soda.
- Avoid sitting continuously, as it may trigger acidity. Take a 5-minute break every hour by brisk walking or stretching.
- Avoid smoking and alcohol consumption. Alcohol intake leads to increased production of stomach acid, thereby increasing acidity and heartburn.
Patients Concern
Disease/Condition Glossary
Gastroesophageal reflux disease (GERD): The stomach is usually protected from acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets irritated or eroded, which leads to complications like GERD, hyperacidity, peptic ulcers, and heartburn. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, a sour or bitter taste in the mouth, and difficulty swallowing.
Peptic ulcers: These are sores that develop on the stomach and intestine lining due to erosion of the stomach's protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion.
Zollinger-Ellison syndrome: It is characterized by the formation of tumours in the upper part of the small intestine, which leads to excess acid production. Symptoms include bloating, burping, weight loss, loss of appetite, nausea, and vomiting.
