OMEPRAZOLE+SODIUM BICARBONATE belongs to a group of medicines called antacids used to treat heartburn, duodenal ulcers, gastroesophageal reflux disease (GERD), and erosive esophagitis (damage to oesophagus due to stomach acid). GERD occurs when stomach acid frequently flows back into the food pipe (oesophagus). Duodenal ulcers are sores that develop on the duodenum's inner lining (first part of the small intestine).
OMEPRAZOLE+SODIUM BICARBONATE is a combination of two drugs: Omeprazole (proton pump inhibitor) and Sodium bicarbonate (antacid). Omeprazole works by blocking an enzyme called gastric proton pump, which is responsible for acid production. Sodium bicarbonate has alkaline pH, which helps in neutralising the acidic pH in the stomach. Together, OMEPRAZOLE+SODIUM BICARBONATE helps to provide relief from acidity.
Take OMEPRAZOLE+SODIUM BICARBONATE 1-2hours prior food. You are advised to take OMEPRAZOLE+SODIUM BICARBONATE for as long as your doctor has prescribed it for you depending on your medical condition. You may experience certain common side-effects such as headache, nausea, vomiting, stomach pain, gas, and diarrhoea in some cases. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
Inform your doctor before taking OMEPRAZOLE+SODIUM BICARBONATE if you have problems with acid-base (pH) balance or low levels of potassium, calcium or magnesium. Talk to your doctor before taking OMEPRAZOLE+SODIUM BICARBONATE if you have osteoporosis: OMEPRAZOLE+SODIUM BICARBONATE may increase the risk of bone fractures on long term treatment. Consult your doctor before taking OMEPRAZOLE+SODIUM BICARBONATE if you are pregnant, planning for pregnancy or breastfeeding. OMEPRAZOLE+SODIUM BICARBONATE may cause drowsiness and dizziness, so drive only if you are alert. OMEPRAZOLE+SODIUM BICARBONATE should not be given to children as the safety have not been established. Avoid consuming alcohol and OMEPRAZOLE+SODIUM BICARBONATE as it could lead to increased drowsiness and elevate stomach acid production.
Heartburn, duodenal ulcers, gastroesophageal reflux disease (GERD) and erosive esophagitis
OMEPRAZOLE+SODIUM BICARBONATE belongs to a group of medicines called antacids used to treat heartburn, duodenal ulcers, gastroesophageal reflux disease (GERD), and erosive esophagitis (damage to oesophagus due to stomach acid). OMEPRAZOLE+SODIUM BICARBONATE is a combination of two drugs, namely: Omeprazole and Sodium bicarbonate. Omeprazole belongs to a group of medicines called proton pump inhibitors, whereas Sodium bicarbonate belongs to a group of medicines called antacids. Omeprazole works by blocking the action of an enzyme called gastric proton pump, which is responsible for acid production. Sodium bicarbonate has alkaline pH, which helps in neutralising the acidic pH in the stomach. Together, OMEPRAZOLE+SODIUM BICARBONATE helps to provide relief from acidity.
Do not take OMEPRAZOLE+SODIUM BICARBONATE if you are allergic to any of its contents, if you are taking rilpivirine or nelfinavir (anti-HIV). Inform your doctor before taking OMEPRAZOLE+SODIUM BICARBONATE if you have severe liver or kidney problems, if you are due to have Chromogranin A test, if you have problems with acid-base (pH) balance, low levels of potassium, calcium or magnesium, if you experience unexplained weight loss, stomach pain, indigestion, vomit food or blood, or if you pass black stools. Talk to your doctor before taking OMEPRAZOLE+SODIUM BICARBONATE if you have osteoporosis, OMEPRAZOLE+SODIUM BICARBONATE may increase the risk of bone fractures on long term treatment. Consult your doctor before taking OMEPRAZOLE+SODIUM BICARBONATE if you are pregnant, planning for pregnancy or breastfeeding. OMEPRAZOLE+SODIUM BICARBONATE may cause drowsiness and dizziness, so drive only if you are alert. OMEPRAZOLE+SODIUM BICARBONATE should not be given to children as the safety have not been established. Avoid consuming alcohol and OMEPRAZOLE+SODIUM BICARBONATE as it could lead to increased drowsiness and elevate stomach acid production.
Drug-Drug Interactions: OMEPRAZOLE+SODIUM BICARBONATE may have interaction with painkillers (aspirin), statin (rosuvastatin, atorvastatin), blood thinner (clopidogrel), a drug used to treat hypothyroidism (levothyroxine), anti-depressant (duloxetine), vitamin (cyanocobalamin), azole antifungals (itraconazole, ketoconazole, posaconazole) and anti-HIV (rilpivirine, nelfinavir).
Drug-Food Interactions: OMEPRAZOLE+SODIUM BICARBONATE may have interaction with St.John’s wort (herbal supplement used to treat depression). Avoiding alcohol consumption as alcohol intake leads to increased stomach acid production, thereby increasing acidity and heartburn.
Drug-Disease Interactions: Inform your doctor if you have Clostridium difficile-associated diarrhoea (CDAD), acid-base balance, sodium-water balance, bone fractures, hypomagnesemia (low levels of magnesium).
Avoid consumption of alcohol while taking OMEPRAZOLE+SODIUM BICARBONATE. Alcohol intake leads to increased production of stomach acid, thereby increases acidity and heartburn.
OMEPRAZOLE+SODIUM BICARBONATE belongs to pregnancy category C. Consult your doctor before taking OMEPRAZOLE+SODIUM BICARBONATE if you are pregnant, your doctor will prescribe only if the benefits outweigh the risks.
OMEPRAZOLE+SODIUM BICARBONATE may pass into breast milk. Consult your doctor before taking OMEPRAZOLE+SODIUM BICARBONATE, your doctor will decide whether OMEPRAZOLE+SODIUM BICARBONATE can be taken by breastfeeding mothers or not.
OMEPRAZOLE+SODIUM BICARBONATE may cause drowsiness and dizziness. Do not drive or operate machinery unless you are alert.
Dose adjustment may be needed. Consult your doctor before taking OMEPRAZOLE+SODIUM BICARBONATE if you have a liver impairment or any concerns regarding this.
Dose adjustment may be needed. Consult your doctor before taking OMEPRAZOLE+SODIUM BICARBONATE if you have kidney impairment or any concerns regarding this.
OMEPRAZOLE+SODIUM BICARBONATE should not be given to children as the safety and effectiveness were not established.
The stomach is usually protected from the acid by a mucous layer. In some cases, due to excess acid production, the mucous layer gets eroded, which leads to complications like heartburn, duodenal ulcers, gastroesophageal reflux disease (GERD) and erosive esophagitis. Gastroesophageal reflux disease (GERD) occurs when stomach acid frequently flows back into the food pipe (oesophagus). This backflow (acid reflux) irritates the food pipe and causes heartburn. Symptoms include heartburn, sour or bitter taste in the mouth, and difficulty swallowing. Duodenal ulcers are sores that develop on the lining of the duodenum (first part of the small intestine) due to erosion of the protective lining. Symptoms include nausea, appetite changes, bloody or dark stools, unexplained weight loss, vomiting, and indigestion. Erosive esophagitis is the inflammation that damages the lining of the oesophagus. Symptoms include difficulty swallowing, painful swallowing, chest pain, heartburn and acid regurgitation.