PALONOSETRON belongs to a class of drugs called antiemetics used to prevent nausea and vomiting during chemotherapy. Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.
PALONOSETRON contains Palonosetron which works by blocking the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting.
Take PALONOSETRON as prescribed by your doctor. You are advised to take PALONOSETRON for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience diarrhoea, constipation, dizziness or headache. Most of these side effects of PALONOSETRON do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to PALONOSETRON or any other medicines, please tell your doctor. PALONOSETRON is not recommended for children. If you are pregnant or breastfeeding, please inform your doctor before taking PALONOSETRON. Drive only if you are alert as PALONOSETRON may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.
Nausea and vomiting
PALONOSETRON contains Palonosetron that blocks the action of serotonin, a chemical that stimulates the vomiting centre (chemoreceptor trigger zone – CTZ) located in the brain. Thus, it prevents nausea and vomiting during chemotherapy.
If you are allergic to PALONOSETRON or any other medicines, please tell your doctor. The oral form is not recommended for children. However, the injection may be given to children above 1 month as advised by a doctor. If you are pregnant or breastfeeding, please inform your doctor before taking PALONOSETRON. Drive only if you are alert as PALONOSETRON may cause tiredness or dizziness. You are recommended to avoid heavy meals and take small nourishing snacks throughout the day. Drink plenty of water to avoid dehydration.
Drug-Drug Interaction: PALONOSETRON may interact with antidepressants (citalopram, fluoxetine, fluvoxamine, paroxetine, sertraline, escitalopram, duloxetine, venlafaxine), heart-related drugs or high blood pressure (quinidine, amiodarone, nicardipine), antibiotics (moxifloxacin, erythromycin), antiemetic (domperidone), antipsychotic drugs (thioridazine, quetiapine, chlorpromazine, haloperidol).
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: If you have blocked bowel, repeated constipation, heart problems or imbalance of potassium and magnesium in the blood, inform your doctor before taking PALONOSETRON.
The interaction of alcohol with PALONOSETRON is unknown. Please consult a doctor before consuming alcohol with PALONOSETRON.
PALONOSETRON is given to pregnant women only if the doctor thinks benefits outweigh risks. Please consult a doctor if you are pregnant.
Please consult a doctor before taking PALONOSETRON if you are breastfeeding. PALONOSETRON is given to breastfeeding women only if the doctor thinks benefits are greater than risks.
PALONOSETRON may cause tiredness or dizziness in some people. Therefore, avoid driving or operating heavy machinery if you feel tired or dizzy after taking PALONOSETRON.
PALONOSETRON may be safe to use in patients with liver problems if prescribed by a doctor.
PALONOSETRON may be safe to use in patients with kidney problems if prescribed by a doctor.
PALONOSETRON is not recommended for children.
Nausea and vomiting: Nausea is a feeling of uneasiness of the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth. In short, nausea and vomiting are not diseases but are symptoms of many conditions like infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). There is a receptor located in our brain known as the chemoreceptor zone (CTZ) that controls vomiting.