About PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE
PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE belongs to the class of medication called ‘cough and cold preparations’ primarily used to treat symptoms of common cold and allergies such as sneezing, runny/stuffy nose, fever, headache, body pains, congestion, or watery eyes. The common cold is a respiratory illness mainly affecting the nasal passage and throat. It is mostly caused by viruses known as ‘rhinoviruses’. The virus enters the body through the nose, mouth, or eyes and spreads easily through droplets in the air when the person who is sick sneezes, coughs, or talks.
PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE is a combination of five drugs, namely: Paracetamol (analgesic and antipyretic), Guaifenesin (expectorant), Ambroxol (mucolytic agent), Chlorpheniramine (antihistamine), and Phenylephrine (decongestant). Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins that are responsible for pain and fever. Guaifenesin is an expectorant that works by reduce the stickiness of mucus and helps to remove it from airways. Ambroxol belongs to the class of mucolytic agents (cough/sputum thinner) that work by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nasal passage. Chlorpheniramine is an antihistamine (anti-allergic drug) that works by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels. Thereby, provides relief from the chest and nasal congestion thereby decreasing mucus production.
Take PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE as prescribed. Your doctor will recommend how often you take PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE based on your medical condition. Some people may experience drowsiness, nervousness, headache, dizziness, flushing (redness of the skin), loss of appetite, diarrhoea, vomiting, insomnia (difficulty in falling or staying asleep), nausea, stomach upset, blurred vision, constipation, and dry mouth, nose or throat. Most of these side effects of PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.
If you are allergic to PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE. Do not use PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE in breastfeeding mothers without a doctor’s advice as it may be excreted in breast milk and cause harm to the baby. Drink plenty of fluids while taking PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE to loosen mucus and protect yourself from being dehydrated or overheated during exercise and in hot weather as PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE contains chlorpheniramine that decreases sweating and increases the risk of heatstroke. If you have high blood pressure, diabetes fits, glaucoma, hyperthyroidism (overactive thyroid), stomach ulcer, chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a congenital disability that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, heart or urinary problems inform your doctor before taking PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE.
Uses of PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE
Common cold symptoms, Allergies
Medicinal Benefits
PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE is a combination of five drugs, namely: Paracetamol, Guaifenesin, Ambroxol, Chlorpheniramine, and Phenylephrine. Paracetamol is a mild pain killer and fever reducer. Guaifenesin is an expectorant that works by reduce the stickiness of mucus and helps to remove it from airways. Ambroxol is a mucolytic agent that decreases the viscosity of the sputum helping for easy coughing. Chlorpheniramine is an anti-allergic that decreases symptoms of allergies like runny/stuffy nose, watery eyes, itchy throat/nasal passage, red eyes, etc. Phenylephrine is a decongestant that works by contracting and narrowing the blood vessels of the nasal passage and airways. Together PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE relieves common cold and allergic symptoms for easy breathing.
Directions for Use
Storage
Side Effects of PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE
- Drowsiness
- Dizziness
- Nervousness
- Headache
- Blurred vision
- Flushing (redness of the skin)
- Loss of appetite
- Diarrhoea
- Nausea
- Vomiting
- Stomach upset
- Constipation
- Insomnia (difficulty in falling or staying asleep)
- Dry mouth, nose or throat
In-Depth Precautions and Warning
Drug Warnings
If you are allergic to PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE or any other medicines, please tell your doctor. If you are pregnant, it is advised to inform your doctor before using PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE. Do not use PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE in breastfeeding mothers without a doctor’s advice as it may be excreted in breast milk and cause harm to the baby. PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE is not recommended for children below 12 years of age. Please do not take more than the prescribed dose of PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE as it may cause liver damage and cause serious adverse effects. Avoid using PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine, and methylene blue injection in the past 14 days. Drink plenty of fluids while taking PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE to loosen mucus and protect yourself from being dehydrated or overheated during exercise and in hot weather as PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE contains chlorpheniramine that decreases sweating and increases the risk of heatstroke. If you have high blood pressure, diabetes, epilepsy (fits), glaucoma, hyperthyroidism (overactive thyroid), stomach ulcer, chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a congenital disease with excess phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE.
Drug Interactions
Drug-Drug Interaction: PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE may interact with anti-allergic drugs (diphenhydramine, cetirizine), antacid (ranitidine), central nervous system stimulants (methylphenidate), antidepressants (duloxetine, sertraline), antibiotics (amoxicillin, doxycycline, cefuroxime, erythromycin), cough suppressants (dextromethorphan), narcotic analgesics (hydrocodone), antianxiety drug (alprazolam).
Drug-Food Interaction: Avoid foods rich in carbohydrates, pectin including jellies, cabbage, Brussels sprouts, and broccoli as PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE may interact with these foods. Also, avoid intake of PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE with chocolate and caffeine-containing foods such as cocoa beans and tea leaves as they may increase the risk of severity of side effects. Avoid consumption of alcohol with PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE as it may increase the risk of liver damage and cause increased drowsiness, dizziness, and difficulty in concentrating.
Drug-Disease Interaction: If you have high blood pressure, diabetes, fits, glaucoma, hyperthyroidism (overactive thyroid), stomach ulcer, chronic bronchitis, asthma, cough with mucus, cough caused by smoking, chronic bronchitis or emphysema (a lung condition causing shortness of breath), chronic obstructive pulmonary disease (COPD), blockage in stomach or intestines, phenylketonuria (a birth defect that causes accumulation of amino acid, phenylalanine in the body), enlarged prostate, pheochromocytoma (tumor in the adrenal glands), kidney, liver, heart or urinary problems, inform your doctor before taking PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid consumption of alcohol with PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE as it may cause increased drowsiness, dizziness or difficulty in concentrating. Please consult a doctor before consuming alcohol with PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE.
Pregnancy
cautionThe safety of PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks benefits outweigh risks.
Breast Feeding
cautionPARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE may be excreted in breast milk and cause harm to the baby. Therefore, PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE should not be used in breastfeeding mothers without doctor’s advice.
Driving
cautionPARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE may cause blurred vision or impair thinking in some people. Therefore, drive only if you are alert after taking PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE.
Liver
cautionTake PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.
Kidney
cautionTake PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.
Children
unsafePARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE may not be recommended for children below 12 years of age. However, please consult a doctor before giving PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE to children.
Habit Forming
Diet & Lifestyle Advise
- Wash your hands with soap and water regularly to prevent the spread of germs.
- Breathing in the steam from a hot shower can minimize cough and cold symptoms.
- Gargle with warm water . It helps in relief from sore throat.
- Keep handkerchief while sneezing to avoid spreading of infection.
- Drink plenty of warm fluids to avoid dehydration.
- Avoid consumption of alcohol with PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE as it may cause tiredness, drowsiness or lack of concentration.
Special Advise
Do not give PARACETAMOL+GUAIFENESIN+AMBROXOL+CHLORPHENIRAMINE+PHENYLEPHRINE to children below 12 years of age.
Patients Concern
Disease/Condition Glossary
Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’ affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at the most significant risk of colds, but healthy adults can also be affected to have 2-3 colds annually. In most cases, cold symptoms are recovered within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like pollutants, dust, etc. The symptoms of the common cold include sneezing, sore throat, cough, congestion, mild body pains, low fever, mild headache, feeling unwell, and stuffy or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.
Allergies: These occur when foreign elements known as allergens attack and invade our body, thereby causing the release of histamines. This chemical messenger 'histamines' causes swelling, inflammation, redness, itchiness, itchy/watery nose and throat, and watery eyes. Allergies generally occur due to chemicals, air pollution, pet danders, dust, pollen hairs, seasonal allergies like hay fever, etc.
