Paracetamol+triprolidine+phenylephrine
About Paracetamol+triprolidine+phenylephrine
Paracetamol+phenylephrine+triprolidine belongs to the class of medications called ‘cough and cold preparations,’ used to treat the common cold and allergic symptoms, such as a runny nose, sneezing, itchy or watery eyes, and a blocked nose. The common cold is an infection of the nose and throat caused by viruses. Allergies are immune system reactions to foreign bodies or allergens such as certain foods, chemicals, pet dander, or pollen.
Paracetamol+phenylephrine+triprolidine is a combination of three medicines: Paracetamol, Triprolidine, and Phenylephrine. Paracetamol is an analgesic (relieves pain) and antipyretic (reduces fever). It works by inhibiting the production of prostaglandins (chemical messengers) that are responsible for pain and fever. Triprolidine belongs to the class of antihistamines (anti-allergic drugs) that work by blocking the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine is a decongestant that works by constricting and narrowing the blood vessels in the nasal passages and airways.
You should take this medicine as prescribed by your doctor. The common side effects of Paracetamol+phenylephrine+triprolidine are nausea, vomiting, dizziness, drowsiness, nervousness, and trouble sleeping. These side effects are usually mild and don’t require medical attention. However, consult your doctor immediately if any of these side effects persist or worsen.
Do not use Paracetamol+phenylephrine+triprolidine if you are allergic to Paracetamol, Triprolidine, Phenylephrine, or any other contents in it. Paracetamol+phenylephrine+triprolidine is not recommended for use in patients suffering from constipation, inability to urinate, stomach blockage, uncontrolled asthma, glaucoma (increased pressure in the eye), high blood pressure, heart diseases, hyperthyroidism (overactive thyroid), diabetes, or intolerance to sugars. Do not take Paracetamol+phenylephrine+triprolidine if you have taken MAO inhibitors (antidepressants) in the last 14 days. Inform your doctor if you are pregnant or breastfeeding.
Uses of Paracetamol+triprolidine+phenylephrine
• Cold Symptom Relief: Paracetamol+phenylephrine+triprolidine is commonly used to address symptoms of the common cold, such as nasal congestion, sneezing, and a runny nose, ensuring better comfort.
• Fever Reduction: Paracetamol+phenylephrine+triprolidine contains ingredients that help lower fever, making it particularly effective for infections or colds accompanied by elevated body temperatures.
• Managing Allergic Rhinitis: Paracetamol+phenylephrine+triprolidine effectively alleviates symptoms of allergic rhinitis, including nasal itching, watery eyes, and sinus pressure.
• Relieving Sinus Headaches: Paracetamol+phenylephrine+triprolidine can help ease sinus headaches caused by sinusitis by reducing nasal inflammation and congestion.
• Cough Management: Paracetamol+phenylephrine+triprolidine provides relief from cough symptoms linked to colds or allergies by reducing mucus production and supporting respiratory health.
Medicinal Benefits
Paracetamol+phenylephrine+triprolidine is a combination of three medicines: Paracetamol, Triprolidine, and Phenylephrine. Paracetamol is an analgesic (relieves pain) and works by inhibiting the production of prostaglandins (chemical messengers) that are responsible for pain. It also has an antipyretic effect (reduces fever). Triprolidine is an antihistamine (an anti-allergic drug) that blocks histamine, a substance responsible for triggering allergic reactions. It also provides relief from allergy symptoms such as sneezing, a runny nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine is a decongestant that works by constricting and narrowing the blood vessels in the nasal passages and airways. Together, Paracetamol+phenylephrine+triprolidine can effectively reduce the symptoms of the common cold and allergies.
Directions for Use
- Paracetamol+phenylephrine+triprolidine can be taken with or without food.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Paracetamol+phenylephrine+triprolidine as a whole with a glass of water.
- Do not crush, break, or chew it.
Storage
Side Effects of Paracetamol+triprolidine+phenylephrine
- Nausea
- Vomiting
- Dizziness
- Drowsiness
- Nervousness
- Trouble sleeping
- Blurred vision
- Dry mouth
Drug Warnings
Paracetamol+phenylephrine+triprolidine should be used with caution in patients with breathing problems, glaucoma (increased pressure in the eye), heart problems, hypertension (high blood pressure), kidney problems, liver disease, seizures (fits), stomach blockage), hyperthyroidism (overactive thyroid), and an enlarged prostate gland (difficulty urinating). Paracetamol+phenylephrine+triprolidine contains sucrose, so use this medicine with caution in patients with diabetes and intolerance to sugars. Paracetamol+phenylephrine+triprolidine may cause drowsiness, so avoid consuming alcohol, as it can exacerbate excessive drowsiness. Also, do not drive or operate heavy machinery if you are drowsy. It should be used with caution in children and elderly patients as they are more prone to side effects. Do not take Paracetamol+phenylephrine+triprolidine if you have taken antidepressants or medicines to treat Parkinson’s disease in the last 14 days.
Drug Interactions
Drug-Drug Interactions: Paracetamol+phenylephrine+triprolidine may interact with other antihistamines (cetirizine and diphenhydramine), medicines used to treat high blood pressure (guanethidine, methyldopa, atenolol, and nifedipine), anticoagulant (warfarin), a medicine used to treat high cholesterol (cholestyramine), a medicine used to treat HIV (zidovudine), anti-emetic drugs (domperidone and metoclopramide), MAO inhibitors (isocarboxazid. linezolid, methylene blue, phenelzine, selegiline, and tranylcypromine, etc.), birth control pills, medications used to treat cough (codeine and hydrocodone), sedatives (alprazolam, lorazepam, and zolpidem), and muscle relaxants (carisoprodol and cyclobenzaprine).
Drug-Food Interactions: No interactions found.
Drug-Disease Interactions: Paracetamol+phenylephrine+triprolidine should be used with caution in patients with constipation, inability to urinate, a stomach blockage, uncontrolled asthma, diabetes, glaucoma (increased pressure in the eye), high blood pressure, heart diseases, and hyperthyroidism (overactive thyroid).
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
cautionAlcohol consumption may increase the risk of side effects such as drowsiness.
Pregnancy
unsafeParacetamol+phenylephrine+triprolidine is a category C medicine and may cause toxic effects to the unborn baby. When clinically necessary, Paracetamol+phenylephrine+triprolidine is administered to pregnant women after a risk-benefit assessment by a doctor.
Breast Feeding
unsafeParacetamol+phenylephrine+triprolidine may pass into breast milk. So, it should be used with caution in breastfeeding mothers.
Driving
unsafeParacetamol+phenylephrine+triprolidine may cause drowsiness. Avoid driving or operating heavy machinery while using this medicine if you feel drowsy.
Liver
cautionParacetamol+phenylephrine+triprolidine should be used with caution in patients with liver diseases. The dose may have to be adjusted by your doctor.
Kidney
cautionParacetamol+phenylephrine+triprolidine should be used with caution in patients with kidney diseases. The dose may have to be adjusted by your doctor.
Children
cautionParacetamol+phenylephrine+triprolidine should be used with caution in children as they are more prone to side effects. The dose may have to be adjusted by your doctor.
Habit Forming
Diet & Lifestyle Advise
- Staying hydrated is vital for those with a cough or cold. Drinking liquids at room temperature can alleviate cough, runny nose, and sneezing.
- The immune system is affected by stress, which raises the risk of illness. An individual can exercise regularly, meditate, practice deep breathing, and employ progressive muscle relaxation techniques to alleviate stress.
- To stay fit and safe, aim to get at least 8 hours of sleep each night.
- It is advised to avoid contact with known allergens (allergy-causing agents) such as pollen, dust, etc. Certain food items are known to cause allergies in you.
Special Advise
Paracetamol+phenylephrine+triprolidine may interfere with certain laboratory tests, such as brain scans for Parkinson's disease and urine drug screening tests, leading to false test results. So, inform your doctor that you are using this medicine before undergoing the tests.
Patients Concern
Disease/Condition Glossary
Common cold: The common cold is an infection caused by the virus, mainly known as ‘rhinoviruses’, affecting the nose and throat (upper respiratory tract). Children younger than 6 years are at a significant risk of contracting colds, but healthy adults can also be affected, with 2-3 colds per year being a common occurrence. In most cases, cold symptoms typically recover within one to two weeks. However, symptoms may last longer in individuals who smoke or are exposed to allergens such as pollutants and dust. The symptoms of the common cold include sneezing, sore throat, cough, congestion, mild body aches, low-grade fever, mild headache, feeling unwell, and a stuffy or runny nose. In some cases, the discharge from the nose may become thicker and yellow or green, which is not an indication of bacterial infection.
Allergies occur when foreign elements, such as allergy-causing agents (allergens), attack and invade the body, causing the release of histamines. This chemical messenger, histamine, causes swelling, inflammation, redness, itchiness, a runny or itchy nose and throat, and watery eyes. Allergies typically occur due to chemicals, air pollution, pet dander, dust, pollen, and seasonal allergies such as hay fever.
FAQs
Paracetamol+phenylephrine+triprolidine is used to treat common cold symptoms and allergic reactions, including runny nose, sneezing, itchy or watery eyes, and a blocked nose.
Paracetamol+phenylephrine+triprolidine is a combination of three medicines: Paracetamol, Triprolidine, and Phenylephrine. Paracetamol blocks the action of chemical messengers that cause pain and fever. Triprolidine blocks the action of histamines that cause allergic reactions. Phenylephrine reduces swelling of the blood vessels in the nasal passages. Together, Paracetamol+phenylephrine+triprolidine can effectively treat symptoms of allergy and the common cold.
Paracetamol+phenylephrine+triprolidine may cause drowsiness and dizziness. Therefore, it is advisable to refrain from activities such as driving or operating heavy machinery until you are fully alert.
It is not recommended to use cetirizine along with Paracetamol+phenylephrine+triprolidine as it may increase side effects such as drowsiness and dizziness. Therefore, it is advisable to consult a doctor before using any medications while taking Paracetamol+phenylephrine+triprolidine.
Paracetamol+phenylephrine+triprolidine should not be used if you have taken antidepressants or drugs used to treat Parkinson's disease in the last 14 days. Therefore, it is always advisable to inform your doctor about all the prescription, non-prescription, and dietary supplements you are taking, to identify any potential interactions with the Paracetamol+phenylephrine+triprolidine.
Paracetamol+phenylephrine+triprolidine can effectively treat and provide relief from allergic symptoms, such as sneezing, a runny or stuffy nose, throat irritation, or watery eyes.
You are recommended not to stop taking Paracetamol+phenylephrine+triprolidine on your own without first consulting your doctor. Although Paracetamol+phenylephrine+triprolidine is generally used for a short duration, continue taking it for the duration advised by your doctor. If you experience any difficulty while using Paracetamol+phenylephrine+triprolidine, please consult your doctor.
No, Paracetamol+phenylephrine+triprolidine does not work for tooth pain. If you experience tooth pain, please consult a dentist for appropriate treatment.
Take Paracetamol+phenylephrine+triprolidine with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.
Do not take Paracetamol+phenylephrine+triprolidine if you have taken antidepressants, which include MAOIs (monoamine oxidase inhibitors), in the last 14 days. Paracetamol+phenylephrine+triprolidine should be used with caution in patients with breathing problems, glaucoma (increased pressure in the eye), heart problems, hypertension (high blood pressure), kidney problems, liver disease, seizures (fits), stomach blockage), hyperthyroidism (overactive thyroid), and an enlarged prostate gland (difficulty urinating).
Store Paracetamol+phenylephrine+triprolidine at room temperature below 30°C in a dry place, protected from light. Keep it out of reach of children.
Paracetamol+phenylephrine+triprolidine may rarely cause serious side effects. If you experience allergic reactions, breathing problems, mouth ulcers, skin rash or peeling, dry mouth, vision disturbances, unexplained bleeding, a fast or irregular heartbeat, or recurrent fevers or infections, inform your doctor immediately.
No, taking a higher dose than the recommended one may not be more effective; instead, it may increase the risk of serious side effects. If your symptoms are not relieved or if the severity of your symptoms increases after using the recommended doses, please consult your doctor.
You are recommended to use Paracetamol+phenylephrine+triprolidine with caution while breastfeeding, as it may pass into the breast milk. Therefore, inform your doctor if you are breastfeeding before starting Paracetamol+phenylephrine+triprolidine.
Paracetamol+phenylephrine+triprolidine contains Paracetamol, which is known to harm the liver, especially when taken in more than recommended doses. Also, avoid alcohol consumption while taking Paracetamol+phenylephrine+triprolidine, as it may further increase the risk of liver damage. Also, Paracetamol+phenylephrine+triprolidine is preferably avoided in patients with underlying liver disease. If you notice any early signs and symptoms of liver damage,e such as yellow skin or eyes, dark urine, fever, stomach pain, nausea, vomiting, loss of appetite, rash, fatigue (overtiredness) and abnormal liver enzymes, contact your doctor immediately.
Paracetamol+phenylephrine+triprolidine contains Paracetamol as one of its active ingredients.
No, Paracetamol+phenylephrine+triprolidine is not an antibiotic. It is a combination medicine used to relieve symptoms of the common cold and allergies.
Paracetamol+phenylephrine+triprolidine is generally recommended for short-term use. Do not take it for an extended period without consulting your doctor. Follow your doctor’s instructions.
Paracetamol+phenylephrine+triprolidine contains Triprolidine, an antihistamine as one of its active ingredients.
The side effects of Paracetamol+phenylephrine+triprolidine include nausea, vomiting, dizziness, drowsiness, trouble sleeping, nervousness, dry mouth and blurred vision. If any of these side effects persist or worsen, please consult your doctor.
