PERAMPANEL belongs to a group of medicines called anticonvulsants or anti-epileptics used to treat epilepsy. Epilepsy is a sudden rush of electricity in the brain. In epilepsy, the brain's electrical rhythms become imbalanced, resulting in recurrent seizures, sometimes leading unconscious state.
PERAMPANEL contains 'Perampanel'. It prevents seizures or epilepsy by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the brain's abnormal and excessive activity of the nerve cells.
In some cases, PERAMPANEL may cause common side effects such as dizziness, drowsiness, increased or decreased appetite, weight gain, fatigue, and nausea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
PERAMPANEL is not recommended during pregnancy and in children below four years. Consult your doctor if you are breastfeeding. PERAMPANEL may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with PERAMPANEL as it could lead to increased dizziness and drowsiness. Consult your doctor immediately if you experience suicidal tendencies. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Epilepsy/seizures
PERAMPANEL belongs to a group of medicines called anticonvulsants or anti-epileptics. PERAMPANEL contains perampanel. It is used to treat epilepsy. PERAMPANEL prevents seizures or epilepsy by blocking a receptor in the brain known as the glutamate receptor, thereby suppressing the abnormal and excessive activity of the nerve cells in the brain.
Do not take PERAMPANEL if you are allergic to any of its contents. Inform your doctor before taking PERAMPANEL if you have serious liver problems, moderate or severe kidney problems, alcoholism, or drug dependence. PERAMPANEL is not recommended during pregnancy and in children below 4 years. Consult your doctor if you are breastfeeding. PERAMPANEL may cause drowsiness and dizziness, so drive only if you are alert. Avoid consuming alcohol along with PERAMPANEL as it could lead to increased dizziness and drowsiness. Keep your doctor informed about your health condition and medicines to rule out any side effects.
Drug-Drug Interactions: PERAMPANEL may interact with medicines used to control seizures/ abnormal excitement in the brain (eslicarbazepine acetate, rufinamide, clobazam, topiramate), and medicine used to treat pain, muscle stiffness and tightness (baclofen).
Drug-Food Interactions: Avoid consumption of alcohol while taking PERAMPANEL.
Drug-Disease Interactions: Inform your doctor if you have suicidal tendencies, elevated triglycerides, liver disease, and kidney dysfunction.
Avoid consumption of alcohol while taking PERAMPANEL as it may increase dizziness and sleepiness.
PERAMPANEL is not recommended during pregnancy.
It is not known if PERAMPANEL passes into breast milk. Please consult your doctor if you have any concerns regarding this. Your doctor will prescribe only if the benefits outweigh the risks.
PERAMPANEL causes drowsiness, sleepiness and tiredness. Do not drive or operate machinery unless you are alert.
Dose adjustment may be needed. Consult your doctor before taking PERAMPANEL if you have a liver impairment or any concerns regarding this. Avoid taking PERAMPANEL if you have serious liver problems.
Dose adjustment may be needed. Consult your doctor before taking PERAMPANEL if you have kidney impairment or any concerns regarding this. Avoid taking PERAMPANEL if you have moderate or serious kidney problems.
PERAMPANEL is not recommended for children below four years. The safety and effectiveness have not been established in children below 4 years of age for partial seizures and below 7 years of age for generalised seizures.
Epilepsy: It is a neurological/central nervous system disorder in which the brain's electrical pattern is disrupted by sudden electrical impulses that affect an individual’s consciousness, movements, or sensations. Possible causes include high fever, trauma, genetic disorder, brain injury or stroke.