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Phenylephrine+paracetamol+cetirizine

About Phenylephrine+paracetamol+cetirizine

Phenylephrine+paracetamol+cetirizine is used to treat common cold and allergic symptoms such as sneezing, watery eyes, and an itchy/watery nose and throat. The common cold is a respiratory illness affecting the nose and throat, mostly caused by the rhinovirus.

Phenylephrine+paracetamol+cetirizine contains Cetirizine, Phenylephrine and Paracetamol. Cetirizine blocks the action of histamine, a substance responsible for causing allergic reactions. Phenylephrine helps shrink the blood vessels in the nasal passage, reducing a stuffy nose. Paracetamol inhibits the production of certain chemical messengers that cause pain and fever.

Some people may experience drowsiness, nausea, fatigue, dry mouth, headache, and vomiting. Most of these side effects do not require medical attention and resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding before starting Phenylephrine+paracetamol+cetirizine. Keep your doctor informed about your health condition and medications to prevent any interactions/side effects.

Uses of Phenylephrine+paracetamol+cetirizine

Phenylephrine+paracetamol+cetirizine is used in the treatment of common cold and allergies (allergic rhinitis). The detailed uses of Phenylephrine+paracetamol+cetirizine are as follows:
• Relief from nasal congestion: Phenylephrine+paracetamol+cetirizine helps to relieve nasal congestion by reducing swelling in the nasal passages, easing breathing, and providing comfort from stuffiness.
• Decreasing symptoms of allergies: Phenylephrine+paracetamol+cetirizine can effectively work in alleviating allergy symptoms like runny nose and sneezing, providing relief from common allergens.
• Reducing fever: Phenylephrine+paracetamol+cetirizine is also involved in reducing fever associated with colds and flu, providing relief and comfort.
• Easing sore throat symptoms: Phenylephrine+paracetamol+cetirizine provides temporary relief from sore throat discomfort, making swallowing and speaking easier.

Medicinal Benefits

  • Phenylephrine+paracetamol+cetirizine is used to treat the common cold and allergy symptoms. It is composed of three medicines, namely, Cetirizine, Phenylephrine, and Paracetamol.
  • Cetirizine belongs to the class of antihistamines (anti-allergic drugs) that work by blocking the action of histamine, a substance responsible for causing allergic reactions.
  • It helps relieve allergy symptoms such as sneezing, a runny nose, watery eyes, itching, swelling, congestion, or stiffness.
  • Phenylephrine helps shrink the blood vessels in the nasal passage, reducing a stuffy nose.
  • Paracetamol is a mild analgesic (relieves pain) and antipyretic (reduces fever) that works by inhibiting the production of certain chemical messengers in the brain known as 'prostaglandins' responsible for pain and fever.
  • Phenylephrine+paracetamol+cetirizine helps relieve symptoms such as a runny nose, blocked nose, sneezing, congestion, pain & fever.

Directions for Use

  • Phenylephrine+paracetamol+cetirizine can be taken with or without food, as advised by your doctor.
  • Follow your doctor's instructions on the dosage and timing of this medication.
  • Swallow Phenylephrine+paracetamol+cetirizine as a whole with a glass of water.
  • Do not crush, chew, or break it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Phenylephrine+paracetamol+cetirizine

  • Drowsiness
  • Nausea
  • Fatigue
  • Dryness in the mouth
  • Headache
  • Vomiting

Drug Warnings

  • Do not take Phenylephrine+paracetamol+cetirizine if you are allergic to any of its ingredients.
  • Avoid taking Phenylephrine+paracetamol+cetirizine if you have taken an MAO inhibitor (anti-depressant medication) in the past 14 days.
  • Please consult your doctor if you are pregnant or breastfeeding before starting Phenylephrine+paracetamol+cetirizine.
  • Inform your doctor if you have high blood pressure,  kidney or liver disease, or coronary artery disease.
  • Phenylephrine+paracetamol+cetirizine may cause drowsiness and sleepiness, so it is advised not to drive a car or operate machinery unless you are alert.
  • Consumption of alcohol should be avoided as it may lead to excessive drowsiness and sleepiness. 
  • Keep your doctor informed about all other medications you are taking.

Drug Interactions

Drug-Drug Interactions: Inform your doctor if you are taking blood thinners (warfarin, aspirin), antibiotics (chloramphenicol), high cholesterol-lowering medicines (cholestyramine), anti-sickness drugs (domperidone, metoclopramide), anti-allergic drugs (diphenhydramine), drugs used to reduce acid in the stomach (pantoprazole), anti-depressants (isocarboxazid, rasagiline, linezolid, tranylcypromine).

Drug-Food Interactions: No interactions found.

Drug-Disease Interactions: If you have high blood pressure, kidney or liver problems, coronary artery disease, or are receiving monoamine oxidase inhibitor (MAO) therapy, inform your doctor before taking Phenylephrine+paracetamol+cetirizine.

Drug-Drug Interactions Checker List:

  • WARFARIN
  • ASPIRIN
  • CHLORAMPHENICOL
  • CHOLESTYRAMINE
  • DOMPERIDONE
  • METOCLOPRAMIDE
  • DIPHENHYDRAMINE
  • PANTOPRAZOLE
  • ISOCARBOXAZID
  • RASAGILINE
  • LINEZOLID
  • TRANYLCYPROMINE
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid consumption of alcohol with Phenylephrine+paracetamol+cetirizine as it may increase drowsiness. Please consult a doctor before consuming alcohol with Phenylephrine+paracetamol+cetirizine.

    • Safety Warning

      Pregnancy

      caution

      The safety of Phenylephrine+paracetamol+cetirizine in pregnant women is unknown. Therefore, it is given to pregnant women only if the doctor thinks the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      The safety of Phenylephrine+paracetamol+cetirizine in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

    • Safety Warning

      Driving

      caution

      Phenylephrine+paracetamol+cetirizine may cause drowsiness or tiredness in some people. Therefore, drive only if you are alert after taking Phenylephrine+paracetamol+cetirizine.

    • Safety Warning

      Liver

      caution

      Take Phenylephrine+paracetamol+cetirizine with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Kidney

      caution

      Take Phenylephrine+paracetamol+cetirizine with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

    • Safety Warning

      Children

      caution

      Phenylephrine+paracetamol+cetirizine is not recommended for children below 12 years of age. However, please consult a doctor before giving Phenylephrine+paracetamol+cetirizine to children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • ​​​​​​Wash your hands with soap and water regularly to prevent the spread of germs.
    • Eat plenty of foods rich in good bacteria, like yoghurt, to improve overall health.
    • Drink plenty of fluids to avoid dehydration.
    • Gargle with salt water for relief from a sore throat.
    • Avoid alcohol consumption with Phenylephrine+paracetamol+cetirizine as it may cause tiredness, drowsiness, or lack of concentration.

    Patients Concern

    Disease/Condition Glossary

    Common cold: The common cold is an infection caused by a virus known as 'rhinovirus' affecting your nose and throat (upper respiratory tract). Children younger than six years of age are at the most significant risk of colds, but healthy adults can also be affected by 2-3 colds annually. In most cases, cold symptoms recover within a week or ten days. However, symptoms might last longer in people who smoke or are exposed to allergens like dust, pollutants, etc. Common cold symptoms might include a stuffy or runny nose, sore throat, cough, congestion, mild body pain or a mild headache, sneezing, low-grade fever, and feeling unwell (malaise). In some cases, the discharge from your nose may become thicker and yellow or green, which does not indicate a bacterial infection. If you observe these symptoms, immediately contact your doctor.

    Allergies: This is a condition that occurs when allergy-causing agents known as 'allergens' attack our body, thereby causing symptoms like redness, a stuffy nose, watery eyes, excess mucus formation, airway irritation, and an itchy and watery nasal passage/throat. During the allergic condition, our body secretes a lot of chemical messengers called 'histamines', which in turn cause all these allergic symptoms. Allergies can be caused by various chemicals, air pollutants, dust, pollen grains of plants, pet dander, hair and multiple medicines.

    FAQs

    Phenylephrine+paracetamol+cetirizine is used to treat the common cold and allergic symptoms like sneezing, watery eyes or itchy/watery nose and throat.

    Phenylephrine+paracetamol+cetirizine is composed of three medicines, namely Cetirizine (antihistamine), Phenylephrine‚ (decongestant), and Paracetamol (analgesic and antipyretic). Cetirizine works by blocking the action of histamine, a substance responsible for causing allergic reactions. It helps relieve allergy symptoms such as sneezing, a runny nose, watery eyes, itching, swelling, congestion, or stiffness. Phenylephrine helps shrink the blood vessels in the nostrils and the passage and reduces stuffy noses. Paracetamol works by inhibiting the production of certain chemical messengers in the brain known as prostaglandins responsible for pain and fever.

    Yes, Phenylephrine+paracetamol+cetirizine contains cetirizine, an antihistamine known to cause dry mouth. Increase the intake of fluids to avoid excessive dry mouth due to Phenylephrine+paracetamol+cetirizine, as continued dryness can lead to dental disease (gum disease, fungal infection, tooth decay).

    No, you are not recommended to take Phenylephrine+paracetamol+cetirizine with warfarin as co-administration of these two medicines may increase bleeding risk more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness, or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

    It is not recommended to take Phenylephrine+paracetamol+cetirizine along with any anti-depressant medication as it contains phenylephrine, which is known to be contraindicated with anti-depressant medications, especially MAO inhibitors. Phenylephrine+paracetamol+cetirizine should be taken at least 15 days after your last dose of antidepressants.

    Yes, Phenylephrine+paracetamol+cetirizine is known to cause nausea or vomiting. In case you are experiencing excessive nausea while consuming Phenylephrine+paracetamol+cetirizine, speak with your doctor.

    Yes, Phenylephrine+paracetamol+cetirizine may cause drowsiness. It is not necessary for everyone taking Phenylephrine+paracetamol+cetirizine to experience this side effect. Therefore, avoid driving if you feel drowsy after taking Phenylephrine+paracetamol+cetirizine.

    Store Phenylephrine+paracetamol+cetirizine at room temperature, in a dry place. Keep it out of sight and reach of children.

    Phenylephrine+paracetamol+cetirizine may cause side effects like drowsiness, nausea, fatigue, dryness in the mouth, headache, and vomiting. Most of these side effects of Phenylephrine+paracetamol+cetirizine do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

    Please consult the doctor if you are breastfeeding. The safety of Phenylephrine+paracetamol+cetirizine in breastfeeding mothers is unknown. Therefore, it is given to breastfeeding mothers only if the doctor thinks the benefits are greater than the risks.

    Phenylephrine+paracetamol+cetirizine is contraindicated in people who are allergic to any of the components in Phenylephrine+paracetamol+cetirizine. Let the doctor know if you have heart problems, stomach ulcers or thyroid problems.

    No, taking a higher than the recommended dose of Phenylephrine+paracetamol+cetirizine will not be more effective but may cause unpleasant side effects. Take Phenylephrine+paracetamol+cetirizine as per the dose advised by the doctor.

    Serious side effects associated with Phenylephrine+paracetamol+cetirizine are allergic reactions, mouth ulcers, breathing problems, irregular heartbeat, or unexplained bleeding. Consult the doctor if you experience any of these side effects.

    Available Medicines for

    Phenylephrine+paracetamol+cetirizine

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