POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE belongs to the class of 'antibiotics' and is primarily used to treat bacterial infections of the external eye and uveitis (inflammation of the middle layer of the eye (uvea)). Bacterial infection occurs when harmful bacteria grow in the body and causes illness. POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE will not work for infections caused by fungi and viruses.
POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE is composed of four medicines: Bacitracin, Hydrocortisone, Neomycin, and Polymyxin B. Bacitracin is a bacteriostatic medicine (stops the growth or reproduction of bacteria). It works by inhibiting bacterial cell wall synthesis. Hydrocortisone belongs to the class of corticosteroids. It blocks the production of prostaglandins (chemical messengers) that make the affected area red, swollen and itchy. On the other hand, Neomycin is an aminoglycoside antibiotic and prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Polymyxin B, an antibiotic, destroys the bacterial membranes by binding to the phospholipids on cell membranes of gram-negative bacteria. This process of binding causes the loss of essential metabolites in bacteria.
Your doctor will advise the appropriate dose that suits your infection. Common side effects of POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE include itching, redness, dryness, and eye irritation. These side effects may not occur in every patient using this medication and differ individually. If the side effects persist longer or worsen, please seek a doctor's advice.
Let your doctor know if you are sensitive to POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE or any other medications. Let your doctor know if you have kidney disease, myasthenia gravis (neuromuscular disease), or Parkinson's disease (a brain disorder that affects movement) before using POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE. Avoid contact of the dispensing container with the eye, eyelids, fingers, and other surfaces to prevent contamination. Pregnant and breastfeeding women should consult their doctor before starting POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE.
Bacterial infections.
POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE treats bacterial eye infections. It comprises four medicines, namely Bacitracin, Hydrocortisone, Neomycin, and Polymyxin B. Bacitracin is a bacteriostatic medicine (stops the growth or reproduction of bacteria) and works by inhibiting the bacterial cell wall synthesis. Bacitracin is active against many gram-positive and some gram-negative bacteria. Hydrocortisone is a corticosteroid and blocks prostaglandins' production (chemical messengers) that make the affected area red, swollen and itchy. Neomycin is an aminoglycoside antibiotic and prevents the synthesis of essential proteins required by bacteria to carry out vital functions. Polymyxin B, an antibiotic, destroys the bacterial membranes by binding to the phospholipids on cell membranes of gram-negative bacteria. This process of binding causes the loss of essential metabolites in bacteria. It is bactericidal against most gram-negative bacteria and has no in-vitro activity against gram-positive bacteria.
Let your doctor know if you are sensitive to POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE or any other medications. Let your doctor know if you have any kidney disease, myasthenia gravis (neuromuscular disease), or Parkinson's disease (a brain disorder that affects movement) before using POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE. Avoid contact of the dispensing container with the eye, eyelids, fingers, and other surfaces to prevent contamination. Let your doctor know if you plan to become pregnant or are already pregnant and a lactating mother. Avoid driving or operating machines since the administration of eye ointment may cause temporary blurred vision for a while after use. POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE should be used for children only when advised by a doctor.
Drug-Drug Interaction: Inform your doctor of all the medications you take, including any eye medicines, before you use POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE.
Drug-Food Interaction: No drug-food interactions found/ established. However, avoiding fatty foods, alcohol, and caffeine can effectively manage bacterial infections.
Drug-Disease Interaction: Brief your doctor if you have a medical history of allergic reactions to medicines, heart, liver and kidney diseases, myasthenia gravis, Parkinson's disease, and other eye problems before using POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE.
No interaction found/ established. Please consult your doctor before using POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE.
It is advised to consult your doctor if you plan to conceive or already pregnant before starting POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE.
There are limited studies on how POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE affects breastfed infants. Please consult your doctor before taking POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE if you are breastfeeding.
POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE may cause side effects like temporary blurry vision, affecting your driving ability. Do not drive or operate machinery in such cases. Drive only when you are alert and have clear vision.
Let your doctor know if you have any history of liver diseases or hepatic impairment. Your doctor will weigh the benefits and potential risks before prescribing POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE.
Let your doctor know if you have any history of kidney diseases. Your doctor will weigh the benefits and potential risks before prescribing POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE.
POLYMYXIN B+NEOMYCIN+BACITRACIN+HYDROCORTISONE should be used for children only If it is prescribed by a doctor.
It is advised to reach out to your doctor if the bacterial infection symptoms persist or worsen after two weeks of treatment.
Bacterial eye infection: A bacterial eye infection occurs when bacteria invade any part of the eyeball or its surrounding tissues, including the cornea (clear front surface of the eye) and the conjunctiva (thin membrane lining the outer eye and inner eyelids). A bacterial eye infection symptoms include red eyes, pain, swelling of the eyes, watery eyes, itching, and blurry vision. Some very common eye infections are conjunctivitis (the inflammation and irritation of the eye's mucous membrane (conjunctiva), stye (bump on the eyelid), uveitis inflammation of the uvea (middle layer of the eye), marginal keratitis (inflammation of the cornea), and blepharitis (inflammation of the eyelids).