Prasugrel+aspirin
About Prasugrel+aspirin
Prasugrel+aspirin is used to prevent the formation of blood clots and to reduce the risk of serious heart/blood vessel problems in the future (such as heart attacks, strokes, and blood clots in stents).
Prasugrel+aspirin contains Prasugrel and Aspirin, which work by preventing platelet aggregation, thereby decreasing the risk of blood clot formation.
Prasugrel+aspirin may cause side effects such as headache, swelling/oedema, dizziness, skin rash, small red bruises, and bruising. If any of these side effects persist or worsen, consult your doctor.
Do not take Prasugrel+aspirin if you are allergic to any of its components. Consult your doctor if you are pregnant or breastfeeding. Keep your doctor informed about your health condition and medications to prevent any interactions.
Uses of Prasugrel+aspirin
Medicinal Benefits
- Prasugrel+aspirin helps prevent the formation of harmful blood clots in the arteries.
- It reduces the risk of heart attack, stroke, and other serious cardiovascular events.
- It helps protect patients who have undergone stent placement by preventing clot formation within the stent.
- Prasugrel+aspirin inhibits platelet aggregation (clumping) and prevents platelets from sticking together.
- It lowers the risk of recurrent heart-related complications in patients with a history of atherothrombotic events.
- Prasugrel+aspirin supports long-term cardiovascular health by improving blood flow and preventing arterial blockage.
Directions for Use
- Prasugrel+aspirin can be taken with or without food, as advised by your doctor. However, if you experience stomach upset, take it with food.
- Follow your doctor's instructions on the dosage and timing of this medication.
- Swallow Prasugrel+aspirin as a whole with a glass of water.
- Do not crush, break, or open it.
Storage
Side Effects of Prasugrel+aspirin
- Headache
- Swelling/oedema
- Dizziness
- Skin rash
- Small red bruises on the skin
- Bruising
Drug Warnings
- Do not take Prasugrel+aspirin if you are allergic to any of its components.
- Inform your doctor if you have/had bleeding from your stomach or intestines, a stroke or a transient ischaemic attack (TIA), liver disease, a recent serious injury, recent surgery (including some dental procedures), kidney (renal) disease, or are 75 years or older.
- Consult your doctor if you are pregnant or breastfeeding.
- Prasugrel+aspirin is not recommended for use in children as the efficacy and safety have not been established.
- Let your doctor know if you are taking any other medicines.
Drug Interactions
Drug-Drug Interaction: Inform your doctor if you are taking anti-coagulants (clopidogrel, dalteparin, enoxaparin, rivaroxaban, warfarin, ticagrelor), antacids (esomeprazole, omeprazole), or painkillers (celecoxib, hydrocodone, ibuprofen, tramadol)
Drug-Food Interaction: No interactions found.
Drug-Disease Interaction: Inform your doctor if you have bleeding, coronary, or cerebral vascular disease, or liver or kidney disease.
Drug-Drug Interactions Checker List:
Safety Advice
Alcohol
unsafeAvoid alcohol consumption while taking Prasugrel+aspirin as it may cause unpleasant side effects. Alcohol intake might increase the risk of stomach or intestinal bleeding.
Pregnancy
cautionIt is recommended to consult your doctor before taking Prasugrel+aspirin in pregnancy, as your doctor will prescribe this drug only if the benefits outweigh the risks.
Breast Feeding
cautionIt is advised to consult your doctor if you are breastfeeding, as in this case, the doctor will prescribe this medicine if the benefits outweigh the risks.
Driving
safe if prescribedPrasugrel+aspirin does not affect the thinking ability to drive. However, do not drive or operate heavy machinery if you are not alert.
Liver
cautionDose modification may be required. Prasugrel+aspirin should be used with care in patients with liver impairment/liver disorder. A person should consult with their specialist if they have liver impairment/liver disease or any concerns regarding this.
Kidney
cautionDose adjustment may be required. Prasugrel+aspirin should be used with care in patients with kidney impairment/kidney disease. Please discuss with your doctor if you have a kidney impairment/kidney disorder or any concerns regarding this.
Children
unsafePrasugrel+aspirin should not be used by children, as the efficacy and safety have not been established.
Habit Forming
Diet & Lifestyle Advise
- It is advised to engage in regular exercise to complement treatment with Prasugrel+aspirin.
- Maintaining a healthy weight with proper diet and exercise is important for good heart health.
- Limit smoking and alcohol consumption, as it may increase the chances of excessive bleeding.
- A person should strictly avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.
- One should eat a nutritious diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
- One should do relaxing activities to manage stress, like meditation, yoga, and massage, which would also help in treating high blood pressure.
Special Advise
- Certain diagnostic tests, such as haemoglobin and hematocrit, can help in checking haemoglobin levels.
- To reduce the risk of cuts, bruises, or other injuries, use caution with sharp objects like razors and nail cutters, and avoid contact sports.
Patients Concern
Disease/Condition Glossary
Blood clot and myocardial infarction: Platelets are very small cell particles that keep circulating in the blood. However, when a blood vessel gets damaged, like if it is cut, then platelets stick together to form a blood clot (thrombus) that prevents further outflow of blood or excessive loss of blood. The formation of clots in arteries can cut off the blood supply, leading to a heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow, which could lead to unstable angina (chest pain). Thus, platelets are important for stopping the bleeding. If clots form within a hardened blood vessel like an artery, then they can cut off the blood supply and even cause a heart attack (myocardial infarction), stroke, or death. The formation of clots in arteries also reduces the blood supply to the heart and even causes unstable angina (severe chest pain).
FAQs
Prasugrel+aspirin is used to prevent the formation of blood clots and avoid the risk of serious heart/blood vessel problems in the future (like heart attacks, strokes, and blood clots in stents).
Prasugrel+aspirin consists of Prasugrel and Aspirin, which inhibit platelet aggregation, thereby reducing the risk of blood clot formation. In this way, Prasugrel+aspirin helps in reducing the risk of cardiovascular events such as myocardial infarction (heart attack) or stroke.
A person taking any anti-coagulant like warfarin is restricted from taking Prasugrel+aspirin as it may increase the risk of bleeding. Consult your doctor for further advice.
Seek medical attention immediately if you develop a medical condition called Thrombotic Thrombocytopenic Purpura (or TTP) that causes fever and bruising under the skin, or notice unexplained extreme tiredness, confusion, yellowing of the skin or eyes (jaundice).
This medicine should not be used in children and adolescents below 18 years of age.
As Prasugrel+aspirin prevents the formation of blood clots, it may increase the risk of bleeding during injury, a cut, or surgery. Thus, consult your doctor if you notice excessive bleeding.
It has been reported that Prasugrel+aspirin may cause anaemia (low haemoglobin and low red blood cell count). So it would be best to take iron-rich food to prevent anaemia.
Yes, Prasugrel+aspirin is a type of blood thinner. It works by preventing platelets (type of blood cells) from sticking together and forming clots.
It is not advised to drink alcohol while taking Prasugrel+aspirin as it can increase the risk of stomach or intestinal bleeding and cause adverse reactions. So it is better to avoid alcohol while using Prasugrel+aspirin.
Yes, you should stop taking Prasugrel+aspirin before surgery. It contains prasugrel and aspirin, which can increase the risk of bleeding. However consult your doctor if you have any concerns.
Prasugrel+aspirin may cause excessive or prolonged bleeding. You should inform your doctor if you notice black tarry stools or if there is blood in the urine. Be aware of any signs of stroke such as sudden numbness or weakness (one side or both sides of the body), difficulty walking, mental confusion, slurred speech, dizziness and any unexplained headache. Please consult your doctor immediately if you develop any such signs.
Prasugrel+aspirin should not be taken by individuals who are allergic to prasugrel, aspirin, or any of the other ingredients in the Prasugrel+aspirin. Avoid taking Prasugrel+aspirin if you have stroke or transient ischemic attack (TIA), liver problems, or stomach ulcers. Therefore, inform your doctor about your medical history before taking Prasugrel+aspirin.
If you forgot to take a dose of Prasugrel+aspirin, do not worry. Take it as soon as you remember. But, if it is time for your next dose, skip the missed dose and take your regular dose. Do not take a double dose to make up for the missed dose.
Your doctor will determine the duration, by considering factors like illness, stent type, and bleeding episodes. Consult your doctor before discontinuing Prasugrel+aspirin as stopping Prasugrel+aspirin suddenly may increase the chances of heart attack, clot formation in the stent, and can even lead to death.
Avoid activities that increase bleeding. Avoid taking painkillers like ibuprofen for joint pain, headache, or backache. Consult your doctor before taking painkillers. Also, avoid excessive alcohol consumption.
