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About RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE

RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE is a combination medicine primarily used to treat first and second-degree burns. It is also indicated in other skin ulcers such as incisions, abrasions, minor cuts and wounds.

RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE contains Recombinant human epidermal growth factor, Chlorhexidine gluconate and Silver sulfadiazine. RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE works by decreasing bacterial growth and healing time. It also increases the tensile strength of the scars, thereby promoting healing.

In some cases, RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE may cause side effects like irritation, itching, pain, and rash. Most of these side effects may not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Let the doctor know if you are allergic to any of the components in RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE. Consult the doctor if you are pregnant or breastfeeding. Keep the doctor informed about your health condition and medications to rule out any side effects/interactions.

Uses of RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE

First and second-degree burns and skin ulcers such as incisions, abrasions, minor cuts and wounds.

Medicinal Benefits

RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE is a synergistic formulation used for burns and wound treatment. RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE contains Recombinant human epidermal growth factor, Chlorhexidine gluconate and Silver sulfadiazine. The recombinant human epidermal growth factor activates by binding with EGF receptors on keratinocytes and fibroblasts. It results in cell proliferation, inhibition of cell death, formation of new blood vessels, and collagen synthesis. Chlorhexidine gluconate has antiseptic & antibacterial properties. It is powerful and non-toxic. It binds to bacterial cell walls and inhibits bacterial growth. Silver sulfadiazine has effective anti-microbial activity and inhibits bacterial synthesis by acting on bacterial cell walls/membranes. Together, RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE helps treat burns. It ensures faster wound healing and also protects the cells from silver toxicity.

Directions for Use

Check the label for directions and apply the medicine to the affected area using a sterile gloved hand and/or sterile spatula as advised by the doctor.

Storage

Store in a cool and dry place away from sunlight

Side Effects of RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE

  • Irritation
  • Itching
  • Rash
  • Pain

In-Depth Precautions and Warning

Drug Warnings

Do not use RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE if you are allergic to any of its components. Inform the doctor if you have hepatic or renal impairment, porphyria (blood disorder), haemolytic anaemia, or glucose-6-phosphate dehydrogenase deficiency. Consult the doctor if you are pregnant or breastfeeding. Let the doctor know if you are using any other medicines, including supplements or herbal products.

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you are taking antacids (cimetidine), inorganic compounds (sodium nitrite), or proteolytic enzymes (collagenase, papain, or sutilains).

Drug-Food Interactions: No interactions found/established.

Drug-Disease Interactions: Inform the doctor if you have porphyria, hepatic or renal impairment.

Drug-Drug Interactions Checker List:

  • CIMETIDINE
  • SODIUM NITRITE
  • COLLAGENASE
  • PAPAIN
  • Safety Advice

    • Safety Warning

      Alcohol

      consult your doctor

      It is unknown if alcohol interacts with RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE. Please consult the doctor if you have any concerns.

    • Safety Warning

      Pregnancy

      caution

      The safe use of silver sulfadiazine has not been established in pregnancy. Please consult the doctor if you are pregnant.

    • Safety Warning

      Breast Feeding

      caution

      The safe use of silver sulfadiazine has not been established in lactation. Please consult the doctor if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      No studies on the effect of RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE on the ability to drive have been established. Drive or operate machinery only if you are alert.

    • Safety Warning

      Liver

      caution

      RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE should not be used if hepatic function becomes impaired. Please consult the doctor if you have liver problems or any concerns regarding this.

    • Safety Warning

      Kidney

      caution

      RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE should not be used if renal function becomes impaired. Please consult the doctor if you have kidney problems or any concerns regarding this.

    • Safety Warning

      Children

      consult your doctor

      Limited information is available. Please consult the doctor if you have any concerns regarding the usage of RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Eat small meals 5-6 times a day.
    • Include fruits, vegetables, and protein in your diet.
    • Stay hydrated by drinking enough fluids.
    • Rest well; get proper sleep.
    • Protect and treat the affected area as advised by the doctor.

    Patients Concern

    Disease/Condition Glossary

    Burns: A burn is an injury to the skin or other tissues primarily caused by heat or due to electricity, radiation, radioactivity, friction or contact with chemicals. Based on the severity of skin damage, burns are categorised into three main types, namely, first-degree (also known as superficial burns, which cause minimal damage to the skin), second-degree (extends beyond the top layer of skin and causes blisters), and third-degree burns (most severe burns extending through every layer of skin). Symptoms include blisters, pain, peeling skin, shock, swelling, and red, white or charred skin.

    FAQs

    How does RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE work?

    RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE offers broad-spectrum antimicrobial activity, helps control wound infection and promotes faster wound healing due to an increased rate of cell proliferation.

    How often should I apply RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE?

    RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE should be re-applied at least every 24 hours. When necessary, RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE should be re-applied to any area from which it has been removed by patient activity. However, you are recommended to re-apply RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE as advised by the doctor.

    Does RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE protect the cells from silver toxicity?

    Yes, RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE protects the cells from silver toxicity. The cytotoxic property of Silver sulfadiazine in retarding wound healing is reversed with the addition of Recombinant human epidermal growth factor.

    Available Medicines for

    RECOMBINANT HUMAN EPIDERMAL GROWTH FACTOR+CHLORHEXIDINE GLUCONATE+SILVER SULFADIAZINE