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About RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE

RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis (TB). Tuberculosis is an infectious disease that mainly affects the lungs but can also spread to other body parts such as kidneys, brain, spine, and bone marrow. 

 

RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE contains Rifampicin, Ethambutol, Isoniazid, Piperine and Pyrazinamide. RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE works by killing the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis). Thus, it helps treat tuberculosis.

 

In some cases, RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE may cause side effects such as nausea, vomiting, stomach pain, headache, and dizziness. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to the doctor if the side effects persist or worsen.

 

Let the doctor know if you are allergic to any of the components in RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE. Consult the doctor before taking RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE if you are pregnant or breastfeeding. RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE may cause dizziness, so drive only if you are alert. Keep the doctor informed about your health condition and medications to rule out any interactions/side effects.

Uses of RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE

Tuberculosis

Medicinal Benefits

RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE belongs to the group of medicines called anti-tuberculosis drugs primarily used to treat tuberculosis. RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE contains Rifampicin, Ethambutol, Isoniazid, Piperine and Pyrazinamide. Rifampicin inactivates the RNA-polymerase enzyme, which is necessary for the bacteria to reproduce and make essential proteins. Pyrazinamide and Ethambutol slow the growth of the bacteria. Isoniazid prevents the formation of bacterial protective covering. Piperine helps increase blood supply and produces substances that fight pain and swelling. Together, RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE helps treat tuberculosis.

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Storage

Store in a cool and dry place away from sunlight

Side Effects of RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE

  • Nausea
  • Vomiting
  • Stomach pain
  • Headache
  • Diarrhoea

In-Depth Precautions and Warning

Drug Warnings

Do not take RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE if you are allergic to any of its components. Inform the doctor if you have diabetes, epilepsy, gout, mental health problems, HIV infection, malnutrition, peripheral neuropathy, porphyria, bleeding problems, kidney or liver problems. Consult the doctor before taking RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE if you are pregnant or breastfeeding. Let the doctor know if you are taking any other medicines, including herbal products and supplements. 

Drug Interactions

Drug-Drug Interactions: Inform the doctor if you take antibiotics (erythromycin) or other medicines, including supplements or herbal products.

Drug-Food Interactions: Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer, while taking RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE as they might cause interaction.

Drug-Disease Interactions: Inform the doctor if you have colitis, peripheral neuropathy, porphyria, gout (high uric acid), or kidney or liver dysfunction.

Drug-Drug Interactions Checker List:

  • ERYTHROMYCIN
  • Safety Advice

    • Safety Warning

      Alcohol

      caution

      Avoid alcohol consumption while taking RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE as it could lead to unpleasant side effects.

    • Safety Warning

      Pregnancy

      caution

      Please consult your doctor if you are pregnant; your doctor will prescribe RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE only if the benefits outweigh the risks.

    • Safety Warning

      Breast Feeding

      caution

      RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE may pass into breast milk. Please consult the doctor if you are breastfeeding.

    • Safety Warning

      Driving

      caution

      RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE may cause dizziness, numbness and tingling in hands and feet. Do not drive or operate machinery if you experience these symptoms.

    • Safety Warning

      Liver

      caution

      Dose adjustment may be needed. Please consult your doctor if you have liver impairment/liver disease before taking RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE.

    • Safety Warning

      Kidney

      caution

      Dose adjustment may be needed. Please consult your doctor if you have any concerns regarding this or if you have kidney impairment/kidney disease before taking RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE.

    • Safety Warning

      Children

      caution

      Please consult the doctor if you have any concerns regarding the usage of RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE in children.

    Habit Forming

    No

    Diet & Lifestyle Advise

    • Pineapple juice might help soothe the symptoms of cough and cold. It also has anti-inflammatory and mucolytic properties.
    • Foods rich in vitamin C, such as kiwi, broccoli, and bell pepper, help improve the immune system. 
    • Avoid processed and fried foods.
    • Warm ginger tea or warm soup can help relieve a cough.
    • Avoid foods and drinks containing histamine or tyramine, such as cured meat, matured cheese, soya, tuna, salmon, mackerel, wine, and beer.
    • Quit smoking and avoid alcohol consumption.

    Patients Concern

    Disease/Condition Glossary

    Tuberculosis (TB): Tuberculosis is an infectious disease that affects the lungs, but it can also spread to other body parts such as kidneys, brain, spine, and bone marrow. Tuberculosis is caused by a bacteria named Mycobacterium tuberculosis. It is a contagious disease which can spread to others through small droplets released into the air by a person suffering from tuberculosis. Symptoms include a cough that lasts for a few weeks, pain while coughing or with normal breathing, unexplained fatigue, fever, night sweats, loss of appetite and weight. People who smoke or consume alcohol, people diagnosed with HIV, and immune system problems are more likely at risk of developing active TB.

    FAQs

    How does RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE work?

    RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE works by killing the bacteria named Mycobacterium tuberculosis, which causes TB (tuberculosis).

    Can I stop taking RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE on my own?

    Do not stop taking RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE despite symptomatic relief. To treat your condition effectually, continue taking RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE for as long as it has been prescribed for you. Talk to the doctor if you have any concerns.

    Does RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE affect contraception?

    RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE might affect contraceptives (birth control pills). Use a reliable barrier method of contraception such as condoms or the coil while taking RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE. Consult your doctor if you have any concerns regarding this; your doctor may suggest an alternate method of contraception.

    Available Medicines for

    RIFAMPICIN+ISONIAZID+PIPERINE+ETHAMBUTOL+PYRAZINAMIDE