ROMIPLOSTIM belongs to the class of 'platelet-stimulating agents' primarily used to treat chronic immune thrombocytopenia in adults who have had an insufficient response to corticosteroids, immunoglobulins, or splenectomy. Immune thrombocytopenia, often called idiopathic thrombocytopenic purpura (ITP), is an immune disorder characterised by low platelet counts.
ROMIPLOSTIM contains 'Romiplostim,' which is a thrombopoietin receptor agonist that functions similarly to thrombopoietin. ROMIPLOSTIM promotes platelet formation by activating the thrombopoietin receptor. Thereby, ROMIPLOSTIM helps treat immune thrombocytopenia effectively.
ROMIPLOSTIM will be administered by the healthcare professional. In some cases, ROMIPLOSTIM may cause common side effects like headache, joint pain, dizziness, trouble sleeping, muscle tenderness or weakness, pain in the arms and legs and indigestion. These side effects may vary individually. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
Notify your doctor if you have allergic reactions to ROMIPLOSTIM or other medications. You must inform your doctor if you have leukaemia (blood or bone marrow cancer), bleeding or clotting disorders, or heart, kidney, or liver problems. ROMIPLOSTIM is not recommended during pregnancy unless indicated by the doctor. ROMIPLOSTIM may make you dizzy; hence drive or operate machinery only when you are alert. ROMIPLOSTIM is not recommended for use during breastfeeding.
Immune thrombocytopenia or idiopathic thrombocytopenic purpura (ITP)
ROMIPLOSTIM contains 'Romiplostim' which belongs to the class of 'thrombopoietin receptor agonists' used to treat low blood platelet count in patients with immune thrombocytopenia. ROMIPLOSTIM promotes platelet formation by activating the thrombopoietin receptor. Thereby, ROMIPLOSTIM helps treat immune thrombocytopenia effectively.
Before beginning ROMIPLOSTIM, notify your doctor if you have had any allergic reactions to ROMIPLOSTIM or any other medications. You must notify your doctor if you have blood or bone marrow cancer (leukaemia), bleeding or clotting disorders, heart, kidney, or liver problems. ROMIPLOSTIM is not recommended during pregnancy unless indicated by the doctor. ROMIPLOSTIM may make you dizzy hence do not attempt to drive or operate machinery until you are physically stable and mentally alert. ROMIPLOSTIM should never be used to normalize platelet counts; ROMIPLOSTIM should only be used in ITP patients whose thrombocytopenia and clinical condition increase the risk of bleeding. ROMIPLOSTIM is not recommended for use during breastfeeding.
Drug-Drug Interactions: ROMIPLOSTIM may interact with anti-cancer medication (e.g. carfilzomib, ibritumomab) and medication used to treat myasthenia gravis (e.g. efgartigimod alfa).
Drug-Food Interactions: No interactions found/established.
Drug-Disease Interactions: ROMIPLOSTIM may interact with disease conditions like leukaemia, liver or kidney impairment.
You are recommended not to consume alcohol along with ROMIPLOSTIM to avoid unpleasant side effects.
ROMIPLOSTIM is not recommended in pregnancy unless indicated by the doctor. Please consult your doctor if you are pregnant or planning to conceive.
Breast-feeding must be avoided during treatment with ROMIPLOSTIM. Please consult your doctor if you have any concerns.
ROMIPLOSTIM may cause dizziness. Hence, it is recommended not to drive or operate machinery until you are mentally alert.
ROMIPLOSTIM is not recommended particularly if you have a history of chronic liver disease/conditions. Please consult your doctor if you have any concerns
Limited information was available for the usage of ROMIPLOSTIM in patients suffering from kidney illness. Please consult your doctor if you have any concerns. Your doctor will prescribe only if the benefits outweigh the risks.
ROMIPLOSTIM is not recommended for children less than one year of age.
Immune thrombocytopenia: It is an immune disorder characterised by low platelet counts and abnormal blood clotting. It happens when the immune system destroys its own platelets by mistake. Immune thrombocytopenia symptoms include easy bruising, bleeding from the gums and nose, blood in the urine and stools, heavy menstruation, and pinpoint-sized reddish-purple patches on the lower thighs.